KR970064298A

KR970064298A - Substituted quinazoline derivatives, methods for their preparation and their use as herbicides

Info

Publication number: KR970064298A
Application number: KR1019960003366A
Authority: KR
Inventors: 안세창; 이병배; 이성민; 배재순; 김정수
Original assignee: 성재갑; 주식회사 Lg 화학
Priority date: 1996-02-12
Filing date: 1996-02-12
Publication date: 1997-09-12

Abstract

본 발명은 하기 일반식 (I)로 표시되는 신규한 제초성 퀴나졸린 유도체, 그의 제조방법 및 이 화합물을 활성성분으로 함유하는 제초제 조성물에 관한 것이다.The present invention relates to a novel herbicidal quinazoline derivative represented by the following general formula (I), a process for producing the same, and a herbicidal composition containing the compound as an active ingredient.

상기 식에서 A는 수소, C-C알킬, C-C알케닐, 또는 C-C알킬, C-C알콕시 및 C-C알콕시카르보닐 중에서 선택된 1 또는 2개의 그룹에 의해 치환되거나 비치환된 피리딘, 피리미딘 또는 티아졸의 헤테로환을 나타내고, X는 산소 또는 황을 나타내며, R은 C-C알킬, C-C알케닐 또는 C-C알킬카르보닐메틸을 나타낸다.Wherein A is hydrogen, C -C Alkyl, C -C Alkenyl, or C -C Alkyl, C -C Alkoxy and C -C Pyrimidine or thiazole, X represents oxygen or sulfur, and R represents C < RTI ID = 0.0 > -C Alkyl, C -C Alkenyl or C -C Alkylcarbonylmethyl.

Description

Substituted quinazoline derivatives, methods for their preparation and their use as herbicides

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is a trivial issue, I did not include the contents of the text.

Claims

A quinazoline derivative of the general formula (I)

Wherein, A is hydrogen, C ₁ -C ₄ alkyl. C ₁ -C ₄ alkenyl, or pyridine substituted or unsubstituted by one or two groups selected from C ₁ -C ₄ alkyl, C ₁ -C ₄ alkoxy and C ₁ -C ₄ alkoxycarbonyl, pyramidine Or thiazole, x represents oxygen or sulfur, and R represents C ₁ -C ₄ alkyl, C ₁ -C ₄ alkenyl or C ₁ -C ₄ alkylcarbonylmethyl.

A process for preparing a compound of the following formula (I-2), characterized in that the hydroxyl group of the compound of the following formula (I-1) is subjected to a nucleophilic substitution reaction with the compound of the formula (IV) in the presence of a base and a solvent.

Wherein R is as defined in claim 1 and A 'is the same as defined in claim 1, with the exception of hydrogen, Q represents fluorine, chlorine bromine or iodine.

A process according to claim 2, wherein the compound of formula (I-1) is prepared by nucleophilic substitution reaction of a compound of formula (II) with a compound of formula (III) in the presence of a solvent and a base.

4. The method according to claim 2 or 3, wherein the solvent is selected from the group consisting of dichloromethane, chloroform, carbon tetrachloride, tetrahydrofuran, diethyl ether, dimethylformamide, dimethylsulfoxide, benzene and toluene.

4. The process according to claim 2 or 3, wherein the base is at least one selected from potassium carbonate, sodium carbonate, sodium hydride and hydrogen carbonate or ternary.

3. The method according to claim 2 or 3, wherein the reaction temperature is room temperature to 150 ° C.

A process for producing a compound represented by the following general formula (I-3), characterized by subjecting a hydroxyl group of the following structural formula (VI) to a nucleophilic substitution reaction with a compound represented by the following general formula (III) in the presence of a solvent and a base.

Wherein A and R are as defined in claim 1 and Q is as defined in claim 2.

8. A process according to claim 7, wherein the compound of formula (VI) is obtained by treatment of the dimethylquinazoline compound of formula (V) with metachloroperbenzoic acid.

A herbicidal composition comprising as an active ingredient a quinazoline derivative of general formula (I) according to claim 1.

※ Note: It is disclosed by the contents of the first application.