KR970061867A - Glutamate derivatives, pharmaceutically acceptable salts thereof and anticonvulsants containing the active ingredients thereof - Google Patents

Glutamate derivatives, pharmaceutically acceptable salts thereof and anticonvulsants containing the active ingredients thereof Download PDF

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Publication number
KR970061867A
KR970061867A KR1019960004377A KR19960004377A KR970061867A KR 970061867 A KR970061867 A KR 970061867A KR 1019960004377 A KR1019960004377 A KR 1019960004377A KR 19960004377 A KR19960004377 A KR 19960004377A KR 970061867 A KR970061867 A KR 970061867A
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South Korea
Prior art keywords
pharmaceutically acceptable
anticonvulsants
acceptable salts
active ingredients
acceptable salt
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KR1019960004377A
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Korean (ko)
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박민수
이재원
최종원
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박민수
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Priority to KR1019960004377A priority Critical patent/KR970061867A/en
Publication of KR970061867A publication Critical patent/KR970061867A/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

본 발명은 글루탐산 유도체 및 약제학적으로 허용가능한 그의 염 및 이를 유효성분으로 하는 항경련제에 관한 것이다.The present invention relates to a glutamate derivative, a pharmaceutically acceptable salt thereof and an anti-convulsant agent containing the same as an active ingredient.

본 발명의 화합물은 기존의 항 경련성 화합물등의 공통된 구조를 하나의 분자내에 포함하고 있어 기존의 항 경련성 화합물보다 광범위한 항 경련활성을 나타낸다.The compound of the present invention contains a common structure such as a conventional anticonvulsant compound in one molecule and exhibits a broader anticonvulsant activity than conventional anticonvulsive compounds.

Description

글루탐산 유도체, 그의 약제학적으로 허용가능한 염 및 이를 유효성분으로 함유하는 항경련제Glutamate derivatives, pharmaceutically acceptable salts thereof, and anticonvulsants containing the same as active ingredients

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is a trivial issue, I did not include the contents of the text.

Claims (3)

하기 일반식(Ⅰ)으로 표시되는 글루탐산 유도체 및 약제학적으로 허용되는 그의 염.A glutamate derivative represented by the following general formula (I) and a pharmaceutically acceptable salt thereof. 상기 식에서, R은 수소, 메틸, 메틸페닐 또는 이소아밀을 나타내며, Cbz는 카르보벤질옥시기를 나타낸다.In the above formula, R represents hydrogen, methyl, methylphenyl or isoamyl, and Cbz represents a carbobenzyloxy group. 제1항에 있어서, 일반식 (Ⅰ)로 표시되는 글루탐산 유도체가 (S)체인 것을 특징으로 하는 글루탐산 유도체 및 그의 허용가능한 염.The glutamate derivative according to claim 1, wherein the glutamate derivative represented by the general formula (I) is (S), and an acceptable salt thereof. 하기 일반식(Ⅰ)로 표시되는 글루탐산 유도체 및 약제학적으로 허용되는 그의 염을 유효성분으로 하는 항경련제.An anticonvulsant comprising the glutamate derivative represented by the following general formula (I) and a pharmaceutically acceptable salt thereof as an active ingredient. 상기 식에서, R은 수소, 메틸, 메틸페닐 또는 이소아밀을 나타내며, Cbz는 카르보벤질옥시기를 나타낸다.In the above formula, R represents hydrogen, methyl, methylphenyl or isoamyl, and Cbz represents a carbobenzyloxy group. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: It is disclosed by the contents of the first application.
KR1019960004377A 1996-02-23 1996-02-23 Glutamate derivatives, pharmaceutically acceptable salts thereof and anticonvulsants containing the active ingredients thereof KR970061867A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019960004377A KR970061867A (en) 1996-02-23 1996-02-23 Glutamate derivatives, pharmaceutically acceptable salts thereof and anticonvulsants containing the active ingredients thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019960004377A KR970061867A (en) 1996-02-23 1996-02-23 Glutamate derivatives, pharmaceutically acceptable salts thereof and anticonvulsants containing the active ingredients thereof

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KR970061867A true KR970061867A (en) 1997-09-12

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4558057A (en) * 1981-12-15 1985-12-10 Burzynski Stanislaw R Purified antineoplaston fractions and methods of treating neoplastic disease
EP0448972A2 (en) * 1990-02-27 1991-10-02 G.D. Searle & Co. Process for preparation of 3-aryl-3-aminoalkyl-2,6-dioxohexahydropyridines
US5112976A (en) * 1985-11-01 1992-05-12 National Research Development Corporation Preparation of 2,6-dioxopiperidine derivatives

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4558057A (en) * 1981-12-15 1985-12-10 Burzynski Stanislaw R Purified antineoplaston fractions and methods of treating neoplastic disease
US5112976A (en) * 1985-11-01 1992-05-12 National Research Development Corporation Preparation of 2,6-dioxopiperidine derivatives
EP0448972A2 (en) * 1990-02-27 1991-10-02 G.D. Searle & Co. Process for preparation of 3-aryl-3-aminoalkyl-2,6-dioxohexahydropyridines

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