KR970032844A - Persistent Expenses - Google Patents

Persistent Expenses Download PDF

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Publication number
KR970032844A
KR970032844A KR1019950066618A KR19950066618A KR970032844A KR 970032844 A KR970032844 A KR 970032844A KR 1019950066618 A KR1019950066618 A KR 1019950066618A KR 19950066618 A KR19950066618 A KR 19950066618A KR 970032844 A KR970032844 A KR 970032844A
Authority
KR
South Korea
Prior art keywords
persistent
agent
dosing agent
inflammatory agent
dosing
Prior art date
Application number
KR1019950066618A
Other languages
Korean (ko)
Inventor
정혜순
민동선
이종율
Original Assignee
김준웅
주식회사 선경인더스트리
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 김준웅, 주식회사 선경인더스트리 filed Critical 김준웅
Priority to KR1019950066618A priority Critical patent/KR970032844A/en
Publication of KR970032844A publication Critical patent/KR970032844A/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

본 발명은 지속성 경비투여제제에 관한 것으로서 더욱 상세하게는 비스테로이드성 소염제, 흡수촉진제 및 점착성 폴리머를 함유하여 비강(鼻腔)을 통해 지속적으로 투여 흡수되는 지속성 경비투여제제 및 그 제조방법에 관한 것이다.The present invention relates to a persistent non-dosing agent, and more particularly, to a persistent non-dosing agent continuously containing and absorbing nonsteroidal anti-inflammatory agents, absorption accelerators and adhesive polymers through the nasal cavity, and a preparation method thereof.

Description

지속성 경비투여제제Persistent Expenses

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

제1도는 본발명의 경비투여제제에 함유되는 비스테로이드성 소염제에 대한 점착성 폴리머의 함량비에 따른 용출율을 나타낸 그래프이고,1 is a graph showing the dissolution rate according to the content ratio of the adhesive polymer to the non-steroidal anti-inflammatory agent contained in the non-administration agent of the present invention,

제2도는 본 발명에서 제조한 경비투여제제의 시간 경과에 따른 용출율을 나타낸 그래프이고,2 is a graph showing the dissolution rate over time of the non-administration agent prepared in the present invention,

제3는 점착성 폴리머의 함유에 의한 시간 경과에 따른 약물 흡수율을 나타낸 그래프이다.Third is a graph showing the drug absorption rate over time due to the inclusion of the adhesive polymer.

Claims (5)

비스테로이성 소염제, 흡수촉진제 및 점착성 폴리머로 이루어진 것임을 특징으로 하는 지속성 경비투여제제.A non-sustainable anti-inflammatory agent, an absorption accelerator and a tacky polymer, characterized in that the continuous non-dosing agent. 제1항에 있어서, 상기 비스테로이드성 소염제는 케토로락인 것임을 특징으로 하는 지속성 경비투여제제.According to claim 1, wherein the nonsteroidal anti-inflammatory agent is a persistent non-dosing agent, characterized in that the ketorolac. 제1항에 있어서, 상기 흡수촉진제는 리소포스파티딜콜린인 것임을 특징으로 하는 지속성 경비투여제제.According to claim 1, wherein the absorption enhancer is a persistent non-dosing agent, characterized in that lysophosphatidylcholine. 제1항에 있어서, 상기 점착성 폴리머는 하이드록시프로필 셀룰로오스(HPC), 하이드록시프로필 메틸셀룰로오스(HPMC), Na-카르보머(Na-carbomer) 및 알긴산 나트륨(Na-alginate) 중에서 선택된 1종 또는 2종 이상의 혼합물인 것임을 특징으로 하는 지속성 경비제제.According to claim 1, wherein the adhesive polymer is one or two selected from hydroxypropyl cellulose (HPC), hydroxypropyl methyl cellulose (HPMC), Na-carbomer (Na-carbomer) and sodium alginate (Na-alginate) Persistence preparations, characterized in that the mixture of more than one species. 비스테로이드성 소염제와 흡수촉진제를 분말화한 다음, 점착성 폴리머 용액에 혼합하고 재건조하는 것을 특징으로 하는 지속성 경비제제의 제조방법.A non-steroidal anti-inflammatory agent and an absorption accelerator are powdered, and then mixed in a tacky polymer solution and re-dried. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019950066618A 1995-12-29 1995-12-29 Persistent Expenses KR970032844A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019950066618A KR970032844A (en) 1995-12-29 1995-12-29 Persistent Expenses

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019950066618A KR970032844A (en) 1995-12-29 1995-12-29 Persistent Expenses

Publications (1)

Publication Number Publication Date
KR970032844A true KR970032844A (en) 1997-07-22

Family

ID=66637382

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019950066618A KR970032844A (en) 1995-12-29 1995-12-29 Persistent Expenses

Country Status (1)

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KR (1) KR970032844A (en)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR890003400A (en) * 1987-08-03 1989-04-14 다까다 데츠오 Bioactive Peptide Powder Composition (Formulation) for Nasal Administration
US4983595A (en) * 1986-05-22 1991-01-08 Syntex (U.S.A.) Inc. Aqueous steroid formulations for nasal administration
WO1993025193A1 (en) * 1992-06-12 1993-12-23 Teijin Limited Pharmaceutical preparation for intra-airway administration
KR950000770A (en) * 1993-06-30 1995-01-03 이원강 Dechlorinated deoxygenated resin composition and storage container using the same
WO1995011042A1 (en) * 1993-10-21 1995-04-27 Hisamitsu Pharmaceutical Co., Inc. Pernasal composition and pernasal preparation containing the same
WO1995028158A1 (en) * 1994-04-13 1995-10-26 Janssen Pharmaceutica N.V. Intranasal antimigraine composition

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4983595A (en) * 1986-05-22 1991-01-08 Syntex (U.S.A.) Inc. Aqueous steroid formulations for nasal administration
KR890003400A (en) * 1987-08-03 1989-04-14 다까다 데츠오 Bioactive Peptide Powder Composition (Formulation) for Nasal Administration
WO1993025193A1 (en) * 1992-06-12 1993-12-23 Teijin Limited Pharmaceutical preparation for intra-airway administration
KR950000770A (en) * 1993-06-30 1995-01-03 이원강 Dechlorinated deoxygenated resin composition and storage container using the same
WO1995011042A1 (en) * 1993-10-21 1995-04-27 Hisamitsu Pharmaceutical Co., Inc. Pernasal composition and pernasal preparation containing the same
WO1995028158A1 (en) * 1994-04-13 1995-10-26 Janssen Pharmaceutica N.V. Intranasal antimigraine composition

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