KR970010736A - Method for producing 2-methyl-4-methoxyaniline - Google Patents

Method for producing 2-methyl-4-methoxyaniline Download PDF

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Publication number
KR970010736A
KR970010736A KR1019950025835A KR19950025835A KR970010736A KR 970010736 A KR970010736 A KR 970010736A KR 1019950025835 A KR1019950025835 A KR 1019950025835A KR 19950025835 A KR19950025835 A KR 19950025835A KR 970010736 A KR970010736 A KR 970010736A
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KR
South Korea
Prior art keywords
methoxyaniline
methyl
aromatic amine
dimethyl sulfate
producing
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Application number
KR1019950025835A
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Korean (ko)
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KR0160008B1 (en
Inventor
이재성
이경희
김재창
김동현
이태진
김기석
강철우
Original Assignee
김만제
학교법인 포항공과대학교
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Priority to KR1019950025835A priority Critical patent/KR0160008B1/en
Publication of KR970010736A publication Critical patent/KR970010736A/en
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Publication of KR0160008B1 publication Critical patent/KR0160008B1/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/74—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

본 발명은 2-메틸-4-메톡시아닐린을 제조하는 방법에 관한 것으로, 일반식(I)의 치환된 방향족 아민 혼합물과 디메틸설페이트를 염기성 첨가물 존재 또는 비존재하에 반응시키는 방법에 의하면 높은 전환율 및 선택도로 2-메틸-4-메톡시아닐린을 제조할 수 있다.The present invention relates to a process for the preparation of 2-methyl-4-methoxyaniline, which comprises reacting a substituted aromatic amine mixture of formula (I) with dimethyl sulfate in the presence or absence of a basic additive, 2-methyl-4-methoxyaniline can be produced by selective treatment.

Description

2-메틸-4-메톡시아닐린의 제조 방법Method for producing 2-methyl-4-methoxyaniline

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is a trivial issue, I did not include the contents of the text.

Claims (7)

하기 일반식(I)의 치환된 방향족 아민 화합물과 디메틸설페이트를 염기성 첨가물 존재 또는 비존재하에 반응시키는 것을 특징으로 하는 2-메틸-4-메톡시아닐린의 제조 방법 :Method for producing 2-methyl-4-methoxyaniline, which comprises reacting a substituted aromatic amine compound represented by the following general formula (I) with dimethyl sulfate in the presence or absence of a basic additive: 상기 식에서 R1및 R2는 각각 독립적으로 H 또는 CH3를 나타낸다. 단, R1, R2및 R3가 동시에 CH3는 아니다.Wherein R 1 and R 2 each independently represent H or CH 3 . However, R 1, R 2 and R 3 are CH 3 at the same time is not. 제1항에 있어서, 상기 일반식(I)의 화합물이 파라아니시딘, 4-아미노-메타크레졸 또는 4-아미노페놀인 것을 특징으로 하는 방법.The method of claim 1, wherein the compound of formula (I) is para anisidine, 4-amino-methacresol or 4-aminophenol. 제1항에 있어서, 상기 방향족 아민에 대한 상기 디메틸설페이트의 첨가량이 몰비로 0.01 내지 100배인 것을 특징으로 하는 방법.2. The method according to claim 1, wherein the amount of the dimethyl sulfate added to the aromatic amine is 0.01 to 100 times by molar ratio. 제3항에 있어서, 상기 방향족 아민에 대한 상기 디메틸설페이트의 첨가량이 몰비로 0.1 내지 5배인 것을 특징으로 하는 방법.4. The method according to claim 3, wherein the amount of dimethyl sulfate added to the aromatic amine is 0.1 to 5 times by molar ratio. 제1항에 있어서, 사염화탄소 용매중에서 반응시키는 것을 특징으로 하는 방법.The method according to claim 1, wherein the reaction is carried out in a carbon tetrachloride solvent. 제1항에 있어서, 상기 반응을 -10℃ 내지 200℃의 온도에서 행하는 것을 특징으로 하는 방법.The process according to claim 1, wherein the reaction is carried out at a temperature of from -10 ° C to 200 ° C. 제1항에 있어서, 상기 염기성 첨가물이 수산화나트륨 또는 수산화칼륨인 것을 특징으로 하는 방법.The method of claim 1, wherein the basic additive is sodium hydroxide or potassium hydroxide. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: It is disclosed by the contents of the first application.
KR1019950025835A 1995-08-22 1995-08-22 Process for 2-methyl-4-methoxyaniline KR0160008B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019950025835A KR0160008B1 (en) 1995-08-22 1995-08-22 Process for 2-methyl-4-methoxyaniline

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019950025835A KR0160008B1 (en) 1995-08-22 1995-08-22 Process for 2-methyl-4-methoxyaniline

Publications (2)

Publication Number Publication Date
KR970010736A true KR970010736A (en) 1997-03-27
KR0160008B1 KR0160008B1 (en) 1999-01-15

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Application Number Title Priority Date Filing Date
KR1019950025835A KR0160008B1 (en) 1995-08-22 1995-08-22 Process for 2-methyl-4-methoxyaniline

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KR0160008B1 (en) 1999-01-15

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