KR970006264A - Novel 6-substituted-5, 8-dioxy-1, 4-naphthoquinone derivatives, methods for their preparation and their use as anticancer agents - Google Patents

Novel 6-substituted-5, 8-dioxy-1, 4-naphthoquinone derivatives, methods for their preparation and their use as anticancer agents Download PDF

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Publication number
KR970006264A
KR970006264A KR1019950021956A KR19950021956A KR970006264A KR 970006264 A KR970006264 A KR 970006264A KR 1019950021956 A KR1019950021956 A KR 1019950021956A KR 19950021956 A KR19950021956 A KR 19950021956A KR 970006264 A KR970006264 A KR 970006264A
Authority
KR
South Korea
Prior art keywords
dioxy
substituted
novel
preparation
methods
Prior art date
Application number
KR1019950021956A
Other languages
Korean (ko)
Other versions
KR0180791B1 (en
Inventor
안병준
용 김
백경업
Original Assignee
안병준
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 안병준 filed Critical 안병준
Priority to KR1019950021956A priority Critical patent/KR0180791B1/en
Priority to PCT/KR1996/000113 priority patent/WO1997003940A1/en
Priority to AU65326/96A priority patent/AU6532696A/en
Publication of KR970006264A publication Critical patent/KR970006264A/en
Application granted granted Critical
Publication of KR0180791B1 publication Critical patent/KR0180791B1/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/29—Saturated compounds containing keto groups bound to rings
    • C07C49/313—Saturated compounds containing keto groups bound to rings polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/007—Esters of unsaturated alcohols having the esterified hydroxy group bound to an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/202—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring the aromatic ring being a naphthalene
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00—Preparation of quinones
    • C07C46/02—Preparation of quinones by oxidation giving rise to quinoid structures
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00—Preparation of quinones
    • C07C46/02—Preparation of quinones by oxidation giving rise to quinoid structures
    • C07C46/06—Preparation of quinones by oxidation giving rise to quinoid structures of at least one hydroxy group on a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/26—Quinones containing groups having oxygen atoms singly bound to carbon atoms
    • C07C50/32—Quinones containing groups having oxygen atoms singly bound to carbon atoms the quinoid structure being part of a condensed ring system having two rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR1019950021956A 1995-07-24 1995-07-24 6-substituted-5,8-dioxy-1,4-naphthoquinone derivative, its preparation process and the usage as anticancer drug KR0180791B1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
KR1019950021956A KR0180791B1 (en) 1995-07-24 1995-07-24 6-substituted-5,8-dioxy-1,4-naphthoquinone derivative, its preparation process and the usage as anticancer drug
PCT/KR1996/000113 WO1997003940A1 (en) 1995-07-24 1996-07-23 Novel 6-substituted-5,8-dioxy-1,4-naphthoquinone derivatives
AU65326/96A AU6532696A (en) 1995-07-24 1996-07-23 Novel 6-substituted-5,8-dioxy-1,4-naphthoquinone derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019950021956A KR0180791B1 (en) 1995-07-24 1995-07-24 6-substituted-5,8-dioxy-1,4-naphthoquinone derivative, its preparation process and the usage as anticancer drug

Publications (2)

Publication Number Publication Date
KR970006264A true KR970006264A (en) 1997-02-19
KR0180791B1 KR0180791B1 (en) 1999-05-15

Family

ID=19421470

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019950021956A KR0180791B1 (en) 1995-07-24 1995-07-24 6-substituted-5,8-dioxy-1,4-naphthoquinone derivative, its preparation process and the usage as anticancer drug

Country Status (3)

Country Link
KR (1) KR0180791B1 (en)
AU (1) AU6532696A (en)
WO (1) WO1997003940A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002076939A2 (en) * 2001-02-05 2002-10-03 Exegenics Inc. Cysteine protease inhibitors
GB0117326D0 (en) * 2001-07-16 2001-09-05 Univ Aberdeen Napthoquinone-type inhibitors of protein aggregation
CN100354253C (en) * 2004-04-23 2007-12-12 中国科学院上海药物研究所 5,8-menadiol diacetate derivatives and their preparing process and use
CN101139287B (en) * 2007-10-11 2010-05-19 上海交通大学 Method for synthesizing alkannin dimethyl ether derivative

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59175449A (en) * 1983-03-26 1984-10-04 Kyushu Kogyo Daigaku Production of shikonin
JPS61143334A (en) * 1984-12-18 1986-07-01 Mitsui Petrochem Ind Ltd 5,8-dehydroxy-1,4-naphthoquinone derivative
JPS62289543A (en) * 1986-06-09 1987-12-16 Nichirei:Kk Antitumor agent and production thereof

Also Published As

Publication number Publication date
KR0180791B1 (en) 1999-05-15
WO1997003940A1 (en) 1997-02-06
AU6532696A (en) 1997-02-18

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