KR970001533B1 - Dihydro derivatives and pseudoaglycons of ll-e33288 antibiotics and anticancer ages, preparation and purification method thereof - Google Patents

Dihydro derivatives and pseudoaglycons of ll-e33288 antibiotics and anticancer ages, preparation and purification method thereof Download PDF

Info

Publication number
KR970001533B1
KR970001533B1 KR88000867A KR880000867A KR970001533B1 KR 970001533 B1 KR970001533 B1 KR 970001533B1 KR 88000867 A KR88000867 A KR 88000867A KR 880000867 A KR880000867 A KR 880000867A KR 970001533 B1 KR970001533 B1 KR 970001533B1
Authority
KR
South Korea
Prior art keywords
pseudoaglycons
ages
anticancer
antibiotics
preparation
Prior art date
Application number
KR88000867A
Other languages
Korean (ko)
Other versions
KR880009132A (en
Inventor
May Dean-Ming Lee
Michael Greenstein
David Paul Labeda
Amedeo Alexander Fantini
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/004,154 external-priority patent/US5037651A/en
Priority claimed from US07/004,153 external-priority patent/US4939244A/en
Priority claimed from US07/009,321 external-priority patent/US4970198A/en
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of KR880009132A publication Critical patent/KR880009132A/en
Application granted granted Critical
Publication of KR970001533B1 publication Critical patent/KR970001533B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/29—Micromonospora

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
KR88000867A 1987-01-30 1988-01-29 Dihydro derivatives and pseudoaglycons of ll-e33288 antibiotics and anticancer ages, preparation and purification method thereof KR970001533B1 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP07/009321 1987-01-30
US07/004,154 US5037651A (en) 1987-01-30 1987-01-30 Dihydro derivatives of LL-E33288 antibiotics
JP07/004153 1987-01-30
US07/004,153 US4939244A (en) 1987-01-30 1987-01-30 Pseudoaglycones of LL-E33288 antibiotics
US07/009,321 US4970198A (en) 1985-10-17 1987-01-30 Antitumor antibiotics (LL-E33288 complex)
JP07/004154 1987-01-30

Publications (2)

Publication Number Publication Date
KR880009132A KR880009132A (en) 1988-09-14
KR970001533B1 true KR970001533B1 (en) 1997-02-11

Family

ID=68282511

Family Applications (1)

Application Number Title Priority Date Filing Date
KR88000867A KR970001533B1 (en) 1987-01-30 1988-01-29 Dihydro derivatives and pseudoaglycons of ll-e33288 antibiotics and anticancer ages, preparation and purification method thereof

Country Status (1)

Country Link
KR (1) KR970001533B1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10081822B2 (en) 2015-05-14 2018-09-25 Cj Cheiljedang Corporation Microorganism of the genus Escherichia producing L-tryptophan and method for producing L-tryptophan using the same
WO2022158645A1 (en) * 2021-01-25 2022-07-28 씨제이제일제당 (주) Novel deoxyguanosinetriphosphate triphosphohydrolase variant, and method for producing l-tryptophan using same

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10081822B2 (en) 2015-05-14 2018-09-25 Cj Cheiljedang Corporation Microorganism of the genus Escherichia producing L-tryptophan and method for producing L-tryptophan using the same
WO2022158645A1 (en) * 2021-01-25 2022-07-28 씨제이제일제당 (주) Novel deoxyguanosinetriphosphate triphosphohydrolase variant, and method for producing l-tryptophan using same

Also Published As

Publication number Publication date
KR880009132A (en) 1988-09-14

Similar Documents

Publication Publication Date Title
EP0214731A3 (en) Antiparasitic avermectin and milbemycin derivatives and process for their preparation
GR880100512A (en) Preparation method of 4-ammonium derivatives of epipodophyllotoxinc glucosite
ZA881835B (en) Avermectin derivatives
IL82251A (en) Polydeoxyribonucleotide defibrotide and process for its preparation
JPS6468378A (en) Novel avermectin derivative, its production and use
NZ220587A (en) Milbemycin derivatives and compositions
AU605218B2 (en) 26-alkenoyloxy derivatives of milbemycin and related macrolides, their preparation and their use
EP0428286A3 (en) 24- and 25-substituted avermectin and milbemycin derivatives
NZ219577A (en) Milbemycin derivatives and compositions
CS505587A3 (en) 4-pyridone derivatives, process of their preparation and pharmaceuticalcompositions comprising them
AU8181187A (en) Lactam derivatives and preparation thereof
ZA894679B (en) Tricyclic 3-oxo-propanenitrile derivatives and process for their preparation
EP0247819A3 (en) Process for producing diadenosine tetraphosphate and derivatives thereof
CS382891A3 (en) N-arylpiperizinealkaneamide derivatives, process of their preparation and pharmaceuticals based thereon
ZA883518B (en) Nitrogen containing derivatives of epipodophyllotoxin glucosides
AU6791787A (en) Macrolide antibiotics and their preparation
KR970001533B1 (en) Dihydro derivatives and pseudoaglycons of ll-e33288 antibiotics and anticancer ages, preparation and purification method thereof
ZA879452B (en) 5-hydroxyethyl derivatives of oxazolidinone-2,their preparation and their therapeutic uses
EP0248401A3 (en) Enzyme and process for its preparation
EP0300674A3 (en) Directed biosynthesis of milbemycin analog
NZ223643A (en) 23-deoxy-27-halo derivatives of ll-f28249 complex macrolides
NZ220677A (en) 7-oxabicycloheptane derivatives and pharmaceutical compositions
EP0242551A3 (en) Process for the preparation of diaziridines and their derivatives
IL85433A0 (en) Milbemycin derivatives,their preparation and their use as pesticides
GB2228482B (en) Preparation of alpha-alkylidene lactones

Legal Events

Date Code Title Description
A201 Request for examination
E902 Notification of reason for refusal
G160 Decision to publish patent application
E701 Decision to grant or registration of patent right
GRNT Written decision to grant
FPAY Annual fee payment

Payment date: 20050630

Year of fee payment: 9

LAPS Lapse due to unpaid annual fee