KR960000865A - Method for preparing pyridine derivative - Google Patents

Method for preparing pyridine derivative Download PDF

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Publication number
KR960000865A
KR960000865A KR1019940014612A KR19940014612A KR960000865A KR 960000865 A KR960000865 A KR 960000865A KR 1019940014612 A KR1019940014612 A KR 1019940014612A KR 19940014612 A KR19940014612 A KR 19940014612A KR 960000865 A KR960000865 A KR 960000865A
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KR
South Korea
Prior art keywords
formula
pyridine derivative
derivative
preparing
preparation
Prior art date
Application number
KR1019940014612A
Other languages
Korean (ko)
Inventor
백성인
김기석
Original Assignee
하기주
주식회사 코오롱
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 하기주, 주식회사 코오롱 filed Critical 하기주
Priority to KR1019940014612A priority Critical patent/KR960000865A/en
Publication of KR960000865A publication Critical patent/KR960000865A/en

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  • Pyridine Compounds (AREA)

Abstract

본 발명은 아래 구조식(I)의 피리딘 유도체를 제조하는 방법에 관한 것으로, 구조식(Ⅱ)의 피리딘 유도체를 클로로화제로서 SOCI2와 반응시켜 구조식(I)의 4-클로로피리딘 유도체를 효율적으로, 고순도, 고수율로 제조하는 새로운 방법을 제공한다.The present invention relates to a method for preparing a pyridine derivative of formula (I), wherein the pyridine derivative of formula (II) is reacted with SOCI 2 as a chloroating agent to efficiently and efficiently purify the 4-chloropyridine derivative of formula (I). It provides a new method of manufacturing in high yield.

식에서, R은 수소 또는 메틸기이다.In the formula, R is hydrogen or methyl group.

본 발명의 방법에 의한 구조식(I)의 화합물은 위궤양 등에 유용한 벤즈이미다졸 유도체의 제조에 필수적인 중간체의 제조에 사용되어, 종래방법에 있어서의 니트로피리딘 산화물을 대체하여 인체에 유해한 단점 및 저수율 등의 비경제성을 극복할 수 있게 한다.The compound of formula (I) according to the method of the present invention is used in the preparation of intermediates essential for the preparation of benzimidazole derivatives useful for gastric ulcers, and the like. Enable to overcome ineconomics

Description

피리딘 유도체의 제조방법Method for preparing pyridine derivative

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음As this is a public information case, the full text was not included.

Claims (1)

구조식(Ⅱ)의 피리딘 유도체를 클로로화제로서 SOCI2와 반응시켜 구조식(I)의 4-클로로피리딘 유도체를 제조하는 방법.A method for preparing 4-chloropyridine derivative of formula (I) by reacting a pyridine derivative of formula (II) with SOCI 2 as a chloroating agent. 식에서, R은 수소 또는 메틸기이다.In the formula, R is hydrogen or methyl group. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019940014612A 1994-06-24 1994-06-24 Method for preparing pyridine derivative KR960000865A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019940014612A KR960000865A (en) 1994-06-24 1994-06-24 Method for preparing pyridine derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019940014612A KR960000865A (en) 1994-06-24 1994-06-24 Method for preparing pyridine derivative

Publications (1)

Publication Number Publication Date
KR960000865A true KR960000865A (en) 1996-01-25

Family

ID=66686401

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019940014612A KR960000865A (en) 1994-06-24 1994-06-24 Method for preparing pyridine derivative

Country Status (1)

Country Link
KR (1) KR960000865A (en)

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E601 Decision to refuse application