KR960000212A - Oral Drug Delivery System Using Hydrophobic Polymer Matrix Containing Hydrophilic Polymer - Google Patents
Oral Drug Delivery System Using Hydrophobic Polymer Matrix Containing Hydrophilic Polymer Download PDFInfo
- Publication number
- KR960000212A KR960000212A KR1019940015569A KR19940015569A KR960000212A KR 960000212 A KR960000212 A KR 960000212A KR 1019940015569 A KR1019940015569 A KR 1019940015569A KR 19940015569 A KR19940015569 A KR 19940015569A KR 960000212 A KR960000212 A KR 960000212A
- Authority
- KR
- South Korea
- Prior art keywords
- drug delivery
- delivery system
- oral drug
- hydrophobic polymer
- water
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Medicinal Preparation (AREA)
Abstract
친수성 약물 및, 수용성 고분자 물질 및 친수성 당류입자중에서 선택된 하나 또는 그 이상을 포함한 소수성 고분자 용액으로 제조된 매트릭스를 사용하는 것을 특징으로 하는 경구용 약물 전달체계는 약물의 방출 속도를 조절하기가 용이하여 적정 시간동안 약물의 농도를 치료영역 내에 존재하게 한다.An oral drug delivery system using a matrix made of a hydrophilic drug and a hydrophobic polymer solution containing one or more selected from water-soluble polymers and hydrophilic sugar particles is easy to control the release rate of the drug. The concentration of drug is allowed to exist in the treatment area over time.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음As this is a public information case, the full text was not included.
제1도는 5-불화우라실 200㎎및 알긴산나트륨 각각 200및 500㎎을 함유한 매트릭스로부터의 5-불화우라실의 방출 프로파일이며,FIG. 1 is the release profile of 5-uraura fluoride from a matrix containing 200 mg 5-urafluoride and 200 mg 500 mg sodium alginate, respectively.
제2도는 5-불화우라실 400㎎및 700㎎을 함유한 매트릭스로부터의 5-불화우라실의 방출 프로파일이다.FIG. 2 is the release profile of 5-urauryl fluoride from a matrix containing 400 mg and 700 mg of 5-urauryl fluoride.
Claims (5)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1019940015569A KR0136211B1 (en) | 1994-06-30 | 1994-06-30 | Oral drug delivery system using lipophilic polymer matrix containing hydrophilic polymer |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1019940015569A KR0136211B1 (en) | 1994-06-30 | 1994-06-30 | Oral drug delivery system using lipophilic polymer matrix containing hydrophilic polymer |
Publications (2)
Publication Number | Publication Date |
---|---|
KR960000212A true KR960000212A (en) | 1996-01-25 |
KR0136211B1 KR0136211B1 (en) | 1998-04-25 |
Family
ID=19386949
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019940015569A KR0136211B1 (en) | 1994-06-30 | 1994-06-30 | Oral drug delivery system using lipophilic polymer matrix containing hydrophilic polymer |
Country Status (1)
Country | Link |
---|---|
KR (1) | KR0136211B1 (en) |
-
1994
- 1994-06-30 KR KR1019940015569A patent/KR0136211B1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
KR0136211B1 (en) | 1998-04-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
A201 | Request for examination | ||
E902 | Notification of reason for refusal | ||
E701 | Decision to grant or registration of patent right | ||
GRNT | Written decision to grant | ||
FPAY | Annual fee payment |
Payment date: 20011122 Year of fee payment: 5 |
|
LAPS | Lapse due to unpaid annual fee |