KR950012072A - Dry test paper for simultaneous detection of various types of drugs using immunoassay and its manufacturing method - Google Patents

Dry test paper for simultaneous detection of various types of drugs using immunoassay and its manufacturing method Download PDF

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KR950012072A
KR950012072A KR1019930020973A KR930020973A KR950012072A KR 950012072 A KR950012072 A KR 950012072A KR 1019930020973 A KR1019930020973 A KR 1019930020973A KR 930020973 A KR930020973 A KR 930020973A KR 950012072 A KR950012072 A KR 950012072A
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South Korea
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antibody
membrane
colored fine
drug
colored
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KR1019930020973A
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Korean (ko)
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KR970010983B1 (en
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최명자
박종세
최정은
송은영
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김은영
한국과학기술연구원
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor

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Abstract

본 발명은 마약류 항체의 반응특이성을 이용하여 두 종류 이상의 마약류를 각각 또는 동시에 검출할 수 있는 간이 건식시험지 및 그것의 제조방법에 관한 것이다.The present invention relates to a simple dry paper and a method for producing the same, which can detect two or more kinds of drugs by using the reaction specificity of the drug antibody.

본 발명의 마약류 검출용 건식시험지는 다른 색깔을 가진 두 종류 이상의 착색 미립자를 각각 검출하고자 하는 마약류의 항체와 접합시켜 이것을 일시적으로 고정시킨 멤브레인과, 마약류 접합프로브가 영구적으로 고정된 멤브레인으로 이루어진다.The dry test paper for drug detection of the present invention consists of a membrane in which two or more colored fine particles having different colors are respectively conjugated with an antibody of a drug to be detected and temporarily fixed thereto, and a membrane in which the drug conjugate probe is permanently fixed.

Description

면역분석법을 이용한, 여러 종류의 마약류 동시검출용 건식시험지 및 그것의 제조방법Dry test paper for simultaneous detection of various types of drugs using immunoassay and its manufacturing method

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

제 1 도는 메탐페타민 검출용 나이트로셀룰로스 맴브레인의 모형도이다,1 is a model diagram of a nitrocellulose membrane for detecting methamphetamine,

제 2 도는 메탐페타민과 몰핀 동시 검출용 나이트로셀를로스 멤브레인의 모형도이다,2 is a schematic diagram of a nitrocell membrane for simultaneous detection of methamphetamine and morphine.

제 3 도는 메탐페타민 검출용 건식시험지의 조립 모형도이다,3 is an assembly model diagram of dry test paper for detecting methamphetamine,

제 4 도는 메탐페타민과 몰핀 동시 검출용 건식시험지의 조립 모형도이다.4 is an assembly model diagram of dry test paper for simultaneous detection of methamphetamine and morphine.

Claims (8)

하나 이상의 착색 미립자,마약류 항체가 일시적으로 고정된 멤브레인과, 하나 이상의 마약류 접합 프로브가 영구적으로 고정된 멤브레인으로 이루어지는, 한 종류 또는 물 이상의 마약류를 각각 또는 동시에 검출하기 위한 건식시험지.A dry paper for the detection of one or more drugs of one or more types or water, each consisting of one or more colored particulates, a membrane temporarily immobilized with an antibody, and a membrane permanently immobilized with one or more drug conjugation probes. 제1항에 있어서, 상기 착색 미립자-마약류 항체의 항체가 메탐메타민항체 또는 몰핀항체인 것을 특정으로 하는 건식시험지.The dry test sheet according to claim 1, wherein the antibody of the colored fine particle-drug antibody is a methamphetamine antibody or a morphine antibody. 제1항에 있어서, 상기 착색 미립자-마약류 항체가 일시적으로 고정된 맴브레인이 유리섬유 멤브레인이고 상기 이상의 마약류 접합 프로브가 영구적으로 고정된 멤브레인이 나이트로셀룰로스 멤브레인인 것을 특징으로 하는 건식시험지.The dry paper according to claim 1, wherein the membrane to which the colored fine particle-drug antibody is temporarily immobilized is a glass fiber membrane and the membrane on which the abnormal drug conjugated probe is permanently immobilized is a nitrocellulose membrane. 제1항에 있어서, 상기 착색 미립자-항체가 종류가 다른 항체를 포함하는 두 종류 이상의 착색 미립자-항체이고, 상기 착색 미립자의 색깔이 서로 다른 것을 특징으로 하는 건식시험지.The dry test paper according to claim 1, wherein the colored fine particles-antibodies are two or more types of colored fine particles-antibodies including different types of antibodies, and the colored fine particles are different in color. a) 검출하고자 하는 마약류의 항체를 제조하고, 이 항체와 착색 미립자를 접합시켜 얻은 착색 미립자-항체를 하나 이상 멤브레인에 분무하고; b) 검출하고자 하는 마약류 프로브를 하나 이상 멤브레인에 처리하고 ; c) 이 두 멤브레인이 서로 같이 방향으로 점하도록 조립하는 것으로 이루어지는, 한 종류 이상의 마약류를 각각 또는 동시에 검출하기 위한 건식시험지의 제조방법.a) preparing an antibody of the drug substance to be detected and spraying one or more membranes with the colored particulate-antibody obtained by conjugating the antibody with the colored particulate; b) treating at least one membrane with the drug substance probe to be detected; c) A method of making a dry paper for detecting one or more drugs, respectively or simultaneously, by assembling the two membranes to point in the same direction to each other. 제5항에 있어서, 상기 착색 미립자-항체의 항체가 메탑페타민항체 또는 몰핀항체인 것을 특징으로 하는 제조방법.The method according to claim 5, wherein the antibody of the colored fine particle-antibody is mettopetamin antibody or morphine antibody. 제5항에 있어서, a)에서의 댐브레인이 유리섬유 맴브레인이고 b)에서의 멤브레인이 나이트로셀룰로스 맴브레인인이 것을 특징으로 하는 제조방법.6. The method of claim 5 wherein the dambrane in a) is a glass fiber membrane and the membrane in b) is a nitrocellulose membrane. 제5항에 있어서, 상기 착색 미립자-항체가 종류가 다른 항체를 포함하는 두 종류 이상의 착색 미립자-항체이고, 상기 착색 미립자의 색깔이 서로 다른 것을 특징으로 하는 제조방법.The production method according to claim 5, wherein the colored fine particle-antibody is at least two kinds of colored fine particle-antibody comprising different kinds of antibodies, and the colored fine particles are different in color. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019930020973A 1993-10-09 1993-10-09 Morphine test and detecting pad and manufacturing method therefor KR970010983B1 (en)

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KR950012072A true KR950012072A (en) 1995-05-16
KR970010983B1 KR970010983B1 (en) 1997-07-05

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20030008748A (en) * 2001-07-20 2003-01-29 한국과학기술연구원 A Immunostrip Paper for the Simultaneous Detection of Philopon and Cannabis
KR20230076618A (en) 2021-11-24 2023-05-31 성균관대학교산학협력단 Kit for drug detection, producing method thereof, and drug detection method using it

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20030008748A (en) * 2001-07-20 2003-01-29 한국과학기술연구원 A Immunostrip Paper for the Simultaneous Detection of Philopon and Cannabis
KR20230076618A (en) 2021-11-24 2023-05-31 성균관대학교산학협력단 Kit for drug detection, producing method thereof, and drug detection method using it
WO2023096284A1 (en) * 2021-11-24 2023-06-01 성균관대학교산학협력단 Drug detection kit, manufacturing method therefor, and drug detection method using same

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