KR940018393A - Chamnoside compound and its extraction method - Google Patents

Chamnoside compound and its extraction method Download PDF

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Publication number
KR940018393A
KR940018393A KR1019930001150A KR930001150A KR940018393A KR 940018393 A KR940018393 A KR 940018393A KR 1019930001150 A KR1019930001150 A KR 1019930001150A KR 930001150 A KR930001150 A KR 930001150A KR 940018393 A KR940018393 A KR 940018393A
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KR
South Korea
Prior art keywords
extracted
compound
present
extract
water layer
Prior art date
Application number
KR1019930001150A
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Korean (ko)
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KR0165564B1 (en
Inventor
김박광
김양배
장성기
박유미
Original Assignee
김박광
홍성소
신일제약 주식회사
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Application filed by 김박광, 홍성소, 신일제약 주식회사 filed Critical 김박광
Priority to KR1019930001150A priority Critical patent/KR0165564B1/en
Publication of KR940018393A publication Critical patent/KR940018393A/en
Application granted granted Critical
Publication of KR0165564B1 publication Critical patent/KR0165564B1/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18—Acyclic radicals, substituted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification
    • C07H1/08—Separation; Purification from natural products

Abstract

본 발명은 유효한 생리활성을 가지는 다음 구조식(Ⅰ)의 화합물 및 그 추출방법에 관한 것이다.The present invention relates to a compound of formula (I) having an effective physiological activity and a method for extracting the same.

식중 R은 하이트록시기 또는 메톡시기이다.Wherein R is a hydroxy group or a methoxy group.

본 발명은 상기 구조식(Ⅰ)의 캄노사이드류는 통상의 화농 및 병원균인 스타필로코거스 균주 및 스트렙토코거스 균주 등에 대하여 높은 항균력을 나타내며, 그 급성독성이 매우 낮아 사람이나 또는 동물의 세균감염증에 효과적으로 사용될 수 있으며, 더구나 본 발명의 화합물은 천연물에서 분리된 물질로서 항균제로서 대단히 유용한 물질이다.The present invention has a high antibacterial activity against the staphylococcus strain and Streptococcus strains, such as normal purulents and pathogens, and the adenotoxicity of the above-mentioned camposides of the structural formula (I) is very low in human or animal bacterial infections. It can be used effectively, and moreover, the compounds of the present invention are very useful as antibacterial agents as substances separated from natural products.

본 발명은 또한 참오동나무를 세절한 다음, 메탄올로 추출한 추출액을 증류수에 현탁시키고, 헥산으로 추출한 추출액을 제거한 물층을 다시 클로로포름으로 추출하고 남은 나머지의 물층을 부탄올로 추출한 후, 부탄을 추출액을 구배(gradient) 실리카겔 칼럼크로마토그래피하여 싱기 구조식(Ⅰ)의 화합물을 제조하는 방법을 제공한다.The present invention also, after cutting the paulownia tree, the extract extracted with methanol is suspended in distilled water, the water layer from which the extract is extracted with hexane is extracted again with chloroform and the remaining water layer is extracted with butanol, and then the butane is gradient (Gradient) Silica gel column chromatography provides a method for preparing a compound of the structure (I).

Description

캄노사이드 화합물 및 그 추출방법Chamnoside compound and its extraction method

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

Claims (2)

다음 일반 구조식(Ⅰ)의 화합물.A compound of the general formula (I) 식중 R은 하이드록시기 또는 메톡시기이다.Wherein R is a hydroxy group or a methoxy group. 참오동나무를 세절한 다음, 메탄올로 추출한 추출액을 증류수에 현탁시키고, 헥산으로 추출한 추출액을 제거한 물층을 다시 클로로포름으로 추출하고 남은 나머지의 물층을 부탄올로 추출한 후, 부탄올 추출액을 구배(gradient) 실리카겔 칼럼크로마토그래피하여 다음 구조식(Ⅰ)의 화합물을 제조하는 방법.After cutting the paulownia tree, the extract extracted with methanol is suspended in distilled water, and the extracted water layer from which the extract extracted with hexane is extracted is extracted with chloroform, and the remaining water layer is extracted with butanol, and the butanol extract is gradient silica gel column. Chromatography to prepare the compound of formula (I). 식중 R은 하이드록시기 또는 메톡시기이다.Wherein R is a hydroxy group or a methoxy group. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019930001150A 1993-01-29 1993-01-29 Campneoside and extraction method thereof KR0165564B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019930001150A KR0165564B1 (en) 1993-01-29 1993-01-29 Campneoside and extraction method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019930001150A KR0165564B1 (en) 1993-01-29 1993-01-29 Campneoside and extraction method thereof

Publications (2)

Publication Number Publication Date
KR940018393A true KR940018393A (en) 1994-08-16
KR0165564B1 KR0165564B1 (en) 1999-01-15

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Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019930001150A KR0165564B1 (en) 1993-01-29 1993-01-29 Campneoside and extraction method thereof

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Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9962326B2 (en) 2010-08-19 2018-05-08 Johnson & Johnson Consumer Inc. Compositions comprising paulownia tomentosa wood extracts and uses thereof
US9387349B2 (en) 2010-08-19 2016-07-12 Johnson & Johnson Consumer Inc. Compositions comprising Paulownia tomentosa wood extracts and uses thereof
US9168219B2 (en) 2010-08-19 2015-10-27 Johnson & Johnson Consumer Inc. Compositions comprising Paulownia tomentosa wood extracts and uses thereof
US9168207B2 (en) 2010-08-19 2015-10-27 Johnson & Johnson Consumer Inc. Compositions comprising Paulownia tomentosa wood extracts and uses thereof
US9168279B2 (en) 2010-08-19 2015-10-27 Johnson & Johnson Consumer Inc. Compositions comprising paulownin and/or Paulownia extracts and uses thereof
US9161958B2 (en) 2010-08-19 2015-10-20 Johnson & Johnson Consumer Inc. Methods of treating cellulite
US9173913B2 (en) 2010-08-19 2015-11-03 Johnson & Johnson Consumer Inc. Compositions comprising Paulownia tomentosa wood extracts and uses thereof

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Publication number Publication date
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