KR940018098A - How to treat alopecia and dermatological problems - Google Patents

Abstract

The present invention provides a method of treating allergen-induced alopecia and other dermatological problems using sensitizing allergens.

Description

How to treat alopecia and dermatological problems

Since this is an open matter, no full text was included.

Claims (20)

1) A small amount of testosterone in aqueous solution is administered to the oral mucosa of male baldness patients to investigate whether it is hypersensitive to testosterone. Administering to the oral mucosa of the patient with hypersensitivity in 1); 3) A method for treating alopecia or abnormal sebum distribution in skin or hair, comprising treating a patient by administering a testosterone sensitized amount in an aqueous solution to the patient. The method of claim 1 wherein the testosterone formulation used for testing and treatment is an aqueous suspension of testosterone propionate. The method of claim 1, wherein testosterone is administered by sublingual route. The method of claim 1, wherein the maintenance amount is between 0.0006 mg and 1 mg per 1-2 days. 5. The method of claim 4, wherein the maintenance amount is 0008 mg to 0.2 mg per 1-2 days. A pharmaceutical composition comprising 0.4 mg / ml to 0.00012 mg / ml of testosterone or an ester of testosterone in an aqueous solution in a sealed container. 1) to test for hypersensitivity to indoor dust and testosterone by administering a reduced amount of testosterone to the patient's oral mucosa and administering a suspension of increasing amounts of indoor dust antigen; 2) in the antigen test performed in step 1), the patient is administered an antigen with hypersensitivity until the sensitized dose is reached; 3) A method for treating alopecia or abnormal sebum distribution in the skin or hair, comprising the step of treating by prolonged administration of the sensitized dose of antigen as measured in step 1). 8. The method of claim 7, wherein the amount of sensitization of the indoor dust is measured by administering an increased amount of antigen. The method of claim 8, wherein the long term treatment is performed using a suspension of 6000 to 10,000 PNU of indoor dust with a small amount of testosterone. 10. The method of claim 9, wherein the long term treatment is performed using an indoor dust antigen suspension of 6000 to 8000 PNU. The composition of claim 6 wherein the active ingredient is testosterone propionate. The composition of claim 6 wherein the active ingredient is testosterone. 7. The composition of claim 6 in a container having a stopper for dispensing the drug in the form of a drop. A kit for testing an immune response to testosterone comprising several compositions according to claim 6 which are diluted differently. 8. The method of claim 7, wherein the treatment is for a long time using indoor dust antigens of 5 PNU to 1000 PNU with trace amounts of testosterone. The method of claim 1, wherein the amount of sensitization is less than 0.0012 mg. The method of claim 16, wherein the amount of sensitization is less than 0.0006 mg. The kit of claim 14, wherein the composition is in a container having a stopper for dispensing the drug in the form of a drop. The method of claim 14, wherein the amount of sensitization is less than 0.0012 mg. The method of claim 16, wherein the amount of sensitization is less than 0.0006 mg. ※ Note: The disclosure is based on the initial application.