KR940013514A - Oral dialysis treatment composition for patients with chronic and terminal renal failure - Google Patents

Oral dialysis treatment composition for patients with chronic and terminal renal failure Download PDF

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Publication number
KR940013514A
KR940013514A KR1019920024103A KR920024103A KR940013514A KR 940013514 A KR940013514 A KR 940013514A KR 1019920024103 A KR1019920024103 A KR 1019920024103A KR 920024103 A KR920024103 A KR 920024103A KR 940013514 A KR940013514 A KR 940013514A
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KR
South Korea
Prior art keywords
weight
parts
renal failure
mannitol
chronic
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Application number
KR1019920024103A
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Korean (ko)
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KR960002848B1 (en
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황일용
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황일용
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Priority to KR1019920024103A priority Critical patent/KR960002848B1/en
Publication of KR940013514A publication Critical patent/KR940013514A/en
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Publication of KR960002848B1 publication Critical patent/KR960002848B1/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys

Abstract

본 발명은 만성 및 말기 신부전증 환자의 치료에 특효가 있는 만니톨(Mannitol)을 주성분으로 하는 경구용 치료제 조성물에 관한 것이다.The present invention relates to an oral therapeutic composition mainly comprising mannitol (Mannitol), which is effective for the treatment of chronic and terminal renal failure patients.

본 발명 경구용 치료제 조성물을 비흡수성 제재인 만니톨 15∼30중량부, NaCl 2∼3중량부, Na2SO44.5∼5.5중량부, KCl 0.7∼0.8중량부, NaHCO31∼2중량부 비율로 조성되는데, 상기 조성물을 물 1ℓ에 용해시켜 하루에 4회 복용하는 것으로 환자의 요독성 물질이 현저하게 제거된다.15-30 parts by weight of mannitol as a non-absorbent agent, 2 to 3 parts by weight of NaCl, 4.5 to 5.5 parts by weight of Na 2 SO 4, 0.7 to 0.8 parts by weight of KCl, and 1 to 2 parts by weight of NaHCO 3. The composition is dissolved in 1 liter of water and taken four times a day to significantly remove the urea substance of the patient.

본 발명 경구용 치료제 조성물에 의한 치료 효과는 신부전증 환자에게 혈액투석이나 복막투석에 의해 일주일에 12시간(일주일에 4시간씩 3번) 치료하는 정도와 같은 효과가 있다.The therapeutic effect of the oral therapeutic composition of the present invention has the same effect as the treatment of renal failure patients with hemodialysis or peritoneal dialysis for 12 hours a week (4 times a week three times).

Description

만성 및 말기 신부전증 환자의 경구용 장투석 치료제 조성물Oral dialysis treatment composition for patients with chronic and terminal renal failure

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음As this is a public information case, the full text was not included.

제1도는 본 발명 실시예 1의 신부전증 치료제 조성물의 치료효과를 나타내는 그라프,1 is a graph showing the therapeutic effect of the renal failure therapeutic composition of Example 1 of the present invention,

제2도는 본 발명 실시예 2의 신부전증 치료제 조성물의 치료효과를 나타내는 그라프.2 is a graph showing the therapeutic effect of the renal failure therapeutic composition of Example 2 of the present invention.

Claims (3)

만니톨(mannitol)을 주성분으로 한 만성 신부전증의 경구용 장투석치료제 조성물.An oral dialysis treatment composition for chronic renal failure based on mannitol. 제1항에 있어서, 만나톨을 제외한 기타 배합성분으로 NaCl, Na2SO4, KCl, NaHCO3를 포함하는 만성 신부전증의 경구용 장투석 치료제 조성물.The oral dialysis therapeutic composition for chronic renal failure according to claim 1, which comprises NaCl, Na 2 SO 4 , KCl, NaHCO 3 as other ingredients except mannitol. 제2항에 있어서, 상기 치료제 조성물을 만니톨이 15∼30중량부, NaCl 2∼3중량부, Na2SO44.5∼5.5중량부, KCl 0.7∼0.8중량부, NaHCO31∼2중량부 함유함을 특징으로 하는 만성 신부전증의 경구용 장투석 치료제 조성물.According to claim 2, wherein the therapeutic composition contains 15 to 30 parts by weight of mannitol, 2 to 3 parts by weight of NaCl, 4.5 to 5.5 parts by weight of Na 2 SO 4, 0.7 to 0.8 parts by weight of KCl, 1 to 2 parts by weight of NaHCO 3 Oral dialysis treatment composition of chronic renal failure characterized in that. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019920024103A 1992-12-14 1992-12-14 The compositions for oral intestinal dialysis of chronic and anaphasal renal insufficiency patients KR960002848B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019920024103A KR960002848B1 (en) 1992-12-14 1992-12-14 The compositions for oral intestinal dialysis of chronic and anaphasal renal insufficiency patients

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019920024103A KR960002848B1 (en) 1992-12-14 1992-12-14 The compositions for oral intestinal dialysis of chronic and anaphasal renal insufficiency patients

Publications (2)

Publication Number Publication Date
KR940013514A true KR940013514A (en) 1994-07-15
KR960002848B1 KR960002848B1 (en) 1996-02-27

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019920024103A KR960002848B1 (en) 1992-12-14 1992-12-14 The compositions for oral intestinal dialysis of chronic and anaphasal renal insufficiency patients

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KR (1) KR960002848B1 (en)

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Publication number Publication date
KR960002848B1 (en) 1996-02-27

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