KR940007187A - Eicosapentaenoic acid and its producing microorganisms by microorganisms - Google Patents
Eicosapentaenoic acid and its producing microorganisms by microorganisms Download PDFInfo
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- KR940007187A KR940007187A KR1019920017473A KR920017473A KR940007187A KR 940007187 A KR940007187 A KR 940007187A KR 1019920017473 A KR1019920017473 A KR 1019920017473A KR 920017473 A KR920017473 A KR 920017473A KR 940007187 A KR940007187 A KR 940007187A
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- South Korea
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- epa
- production
- microorganisms
- chlorella
- eicosapentaenoic acid
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- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
에이코사펜타엔산(Eicosapentaenoic acid)은 탄소수 20개, 5.8.11.14.17번 탄소에 이중결합을 가지고 있는 ω-3계열의 고도불포화 지방산으로 혈장지질구성의변화를 유도하여 활관성질환 및 동맥경화성질환의 예방과 치료에 효과가 있다고 알려져 있다. 이러한 효과가 있는 EPA는 등푸른 바다생선인 고등어, 정어리로부터 추출하여 생산되고 있으나 추출물에 잔존하게 되는 비린내로 인한 품질저하와 일정한 원료공급에 문제점이 있다.Eicosapentaenoic acid is a polyunsaturated fatty acid of ω-3 series having 20 carbon atoms and a double bond to carbon number 5.8.11.14.17. It is known to be effective in the prevention and treatment of diseases. EPA having such an effect is produced by extracting from blue sea fish such as mackerel and sardines, but there are problems in the quality deterioration and supply of certain raw materials due to the fishy smell remaining in the extract.
이와 같은 문제점을 해결하기 위하여 곰팡이, 조류 및 클로렐라(Chlorella)로부터 EPA생산을 검토하여 모티어렐라속(Motierella)과 클로렐라속(Chlorella)등이 분리되었지만 대부분 증식속도가 늦고 대량 배양방법 등에 문제가 있어서 산업화되지 못하고 있는 실정이다.In order to solve this problem, Motiella and Chlorella have been separated from the fungus, algae and Chlorella by examining EPA production. It is not industrialized.
따라서 본 발명자들은 EPA의 생산을 위하여 어류의 세균으로부터 EPA생산균의 분리를 시도하였고 분리균주를 동정하여 슈도모나스속(Pseudomonas sp.)으로 확인하였다. 본 발명의 균주를 이용하면 빠른 증식속도와 간단한 배양방법에 의하여 EPA 생산이 가능하여 생산비용이 절감되고 저렴한 가격으로 대량생산이 가능할 것으로 생각된다.Therefore, the present inventors attempted to isolate EPA-producing bacteria from fish bacteria for the production of EPA, and identified the isolated strain as Pseudomonas sp. By using the strain of the present invention, it is thought that EPA can be produced by a fast growth rate and a simple culture method, thereby reducing the production cost and enabling mass production at a low price.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.
제1도는 본 발명에서 분리된 EPA 생산균주의 전자현미경 사진이다.1 is an electron micrograph of the EPA producing strain isolated in the present invention.
제2도는 본 균주가 생산사는 EPA와 표준 EPA를 비교한 씬 레이어 크로마토그래피(thin layer chromatogaphy)사진이다.2 is a thin layer chromatogaphy photograph of the strain comparing the EPA to the standard EPA.
제3도는 본 균주가 생산하는 지방산의 가스 크로마토그래피(gas chromatogaphy)도면이다.3 is a gas chromatogaphy diagram of fatty acids produced by the strain.
Claims (2)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1019920017473A KR940007187A (en) | 1992-09-25 | 1992-09-25 | Eicosapentaenoic acid and its producing microorganisms by microorganisms |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1019920017473A KR940007187A (en) | 1992-09-25 | 1992-09-25 | Eicosapentaenoic acid and its producing microorganisms by microorganisms |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR940007187A true KR940007187A (en) | 1994-04-26 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019920017473A KR940007187A (en) | 1992-09-25 | 1992-09-25 | Eicosapentaenoic acid and its producing microorganisms by microorganisms |
Country Status (1)
| Country | Link |
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| KR (1) | KR940007187A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100763007B1 (en) * | 2006-05-09 | 2007-10-04 | 전남대학교산학협력단 | Antibiotics comprising eicosapentaenoic acid as an active ingredient strain producing the ingredient producing method and use thereof |
-
1992
- 1992-09-25 KR KR1019920017473A patent/KR940007187A/en not_active Application Discontinuation
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100763007B1 (en) * | 2006-05-09 | 2007-10-04 | 전남대학교산학협력단 | Antibiotics comprising eicosapentaenoic acid as an active ingredient strain producing the ingredient producing method and use thereof |
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