KR940006987A - Novel Hydroquinone Derivatives - Google Patents

Novel Hydroquinone Derivatives Download PDF

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Publication number
KR940006987A
KR940006987A KR1019920017357A KR920017357A KR940006987A KR 940006987 A KR940006987 A KR 940006987A KR 1019920017357 A KR1019920017357 A KR 1019920017357A KR 920017357 A KR920017357 A KR 920017357A KR 940006987 A KR940006987 A KR 940006987A
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South Korea
Prior art keywords
alkyl group
group
hydroquinone derivatives
carbon atoms
alkoxy group
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KR1019920017357A
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Korean (ko)
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KR100228594B1 (en
Inventor
사또오 토시오
마쓰모또 히또시
니이로 야수노리
Original Assignee
미끼도쿠타로오
니폰 하이폭스 라보레토리즈 인코포레이티드
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Priority to KR1019920017357A priority Critical patent/KR100228594B1/en
Publication of KR940006987A publication Critical patent/KR940006987A/en
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K15/00—Anti-oxidant compositions; Compositions inhibiting chemical change
    • C09K15/04—Anti-oxidant compositions; Compositions inhibiting chemical change containing organic compounds
    • C09K15/06—Anti-oxidant compositions; Compositions inhibiting chemical change containing organic compounds containing oxygen
    • C09K15/08—Anti-oxidant compositions; Compositions inhibiting chemical change containing organic compounds containing oxygen containing a phenol or quinone moiety
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B5/00—Preserving by using additives, e.g. anti-oxidants

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Wood Science & Technology (AREA)
  • Materials Engineering (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

본 발명은 항산화활성 및 종양발생억제활성을 갖는 화합물로서 화학식(Ⅰ)및 (Ⅱ)의 신규한 히드로퀴논 유도체들 및 활성성분으로서 화학식(Ⅲ)의 히드로퀴논 유도체 및/또는 그의 염을 함유하는 항산화제 및 종양발생역 제제를 제공한다.The present invention relates to novel hydroquinone derivatives of formulas (I) and (II) as compounds having antioxidant and tumorigenic activity and to antioxidants containing hydroquinone derivatives of formula (III) and / or salts thereof as active ingredients and Provided oncogenic agents.

상기 식에서, R1은 7내지 11개의 탄소원자를 갖는 알킬기이고, R2내지 R5각각은 R2내지 R5의 적어도 하나의 저급 알킬기 또는 저급 알콕시기가 되도록 제공된, 독립적으로 수소원자, 저급 알킬기 또는 저급 알콕시기이며, R7내지 R10각각은 독립적으로 수소원자, 저급 알킬기 또는 저급 알콕시기이고, 그리고 R6및 R11은 적어도 2개의 탄소원자의 탄소사슬을 갖는 알킬기이다.Wherein, R 1 is an alkyl group having from 7 to 11 carbon atoms, R 2 to R 5 each of R 2 to the supplied to group at least one lower alkyl group or lower alkoxy group of R 5, independently represent a hydrogen atom, a lower alkyl group or a lower An alkoxy group, each of R 7 to R 10 is independently a hydrogen atom, a lower alkyl group or a lower alkoxy group, and R 6 and R 11 are alkyl groups having a carbon chain of at least two carbon atoms.

Description

신규한 히드로퀴논 유도체Novel Hydroquinone Derivatives

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

제1도는 α, α-디페닐-β-피크릴히드라질(DPPH)제거능력에 대한 시험 결과를 나타내는 그래프이다.1 is a graph showing test results for α, α-diphenyl-β-picrylhydrazyl (DPPH) removal ability.

Claims (4)

화학식(Ⅰ)의 히드로퀴논 유도체.Hydroquinone Derivatives of Formula (I). 상기식에서, R1은 7내지 11개의 탄소원자를 갖는 알킬기이다.Wherein R 1 is an alkyl group having 7 to 11 carbon atoms. 화학식(Ⅱ)의 히드로퀴논 유도체.Hydroquinone derivatives of formula (II). 상기식에서, R2내지 R5각각은 R2내지 R5의 적어도 하나의 저급 알킬기 또는 저급 알콕시기가 되도록 제공되, 독립적으로 수소원자, 저급 알킬기 또는 저급 알콕시기이고, 그리고 R6는 적어도 2개의 탄소원자의 탄소사슬을 갖는 알킬기이다.Wherein R, R 2 to R 5 each of R 2 to provided to group the at least one lower alkyl group or lower alkoxy group of R 5, independently represent a hydrogen atom, a lower alkyl group or a lower alkoxy group, and R 6 is at least two carbon atoms It is an alkyl group which has a carbon chain. 활성성분으로서, 화학식(Ⅲ)의 히드로퀴논 유도체 및/또는 그의 염을 함유하는 황산화제.Sulfating agents containing, as active ingredient, hydroquinone derivatives of formula (III) and / or salts thereof. 상기식에서, R7내지 R10각각은 독립적으로 수소원자, 저급 알킬기 또는 저급 알콕시기이고, 그리고 R11은 적어도 2개의 탄소원자의 탄소사슬을 갖는 알킬기이다.Wherein R 7 to R 10 are each independently a hydrogen atom, a lower alkyl group or a lower alkoxy group, and R 11 is an alkyl group having a carbon chain of at least two carbon atoms. 활성성분으로서, 화학식(Ⅲ)의 히드로퀴논 유도체 및/또는 그의 염을 함유하는 종양발생억제제.An oncogenic inhibitor comprising as an active ingredient a hydroquinone derivative of formula (III) and / or a salt thereof. 상기식에서, R7내지 R10각각은 독립적으로 수소원자, 저급 알킬기 또는 저급 알콕시기이고, 그리고 R11은 적어도 2개의 탄소원자의 탄소사슬을 갖는 알킬기이다.Wherein R 7 to R 10 are each independently a hydrogen atom, a lower alkyl group or a lower alkoxy group, and R 11 is an alkyl group having a carbon chain of at least two carbon atoms. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019920017357A 1992-09-23 1992-09-23 Hydroquinone derivative KR100228594B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019920017357A KR100228594B1 (en) 1992-09-23 1992-09-23 Hydroquinone derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019920017357A KR100228594B1 (en) 1992-09-23 1992-09-23 Hydroquinone derivative

Publications (2)

Publication Number Publication Date
KR940006987A true KR940006987A (en) 1994-04-26
KR100228594B1 KR100228594B1 (en) 1999-11-01

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Application Number Title Priority Date Filing Date
KR1019920017357A KR100228594B1 (en) 1992-09-23 1992-09-23 Hydroquinone derivative

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