KR940003567A - Method for preparing intravenous gamma globulin with immunoglobulins A and M removed - Google Patents
Method for preparing intravenous gamma globulin with immunoglobulins A and M removed Download PDFInfo
- Publication number
- KR940003567A KR940003567A KR1019920014494A KR920014494A KR940003567A KR 940003567 A KR940003567 A KR 940003567A KR 1019920014494 A KR1019920014494 A KR 1019920014494A KR 920014494 A KR920014494 A KR 920014494A KR 940003567 A KR940003567 A KR 940003567A
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- KR
- South Korea
- Prior art keywords
- polyethylene glycol
- sodium chloride
- immunoglobulins
- buffer solution
- gamma globulin
- Prior art date
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
본 발명은 콘 분획 II 또는 II+III페이스트를 풀리에틸렌글리콜-염화나트륨-초산염 완충응액에 현탁한 후 용해되지 않는 응집체를 제거하고, DEAE-이온 교환 수지 크로마토그래피하는 단계를 포함하는 면역글로불린 A 및 M이 제거된 정맥주사용 강마글로불린제의 제조방법을 제공하는 것이다.The present invention comprises immunoglobulin A and M comprising suspending the cone fraction II or II + III paste in pulleyethylene glycol-sodium chloride-acetate buffer, removing the insoluble aggregates, and chromatography with DEAE-ion exchange resin. It is to provide a method for producing the removed intravenous gangmaglobulin agent.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.
제1(가)도는 본 발명에 따라 폴리에틸렌글리콜 처리후 DE.7E-이온교환 크로마토그래피전에 얻어진 시료를 겔 여과 크로마토그래피한 겪과이고, 제1 (나)도는 본 발명에 따라 폴리에틸렌 글리콜 처리 및 DEAE-이온교환 크로마토그래피후에 얻어진 시료를 겔 여과 크로마토그래피한 결과이며,Figure 1 (a) shows the result of gel filtration chromatography of the sample obtained before the DE.7E-ion exchange chromatography after polyethylene glycol treatment according to the present invention, and Figure 1 (b) shows the polyethylene glycol treatment and DEAE according to the present invention. It is the result of the gel filtration chromatography of the sample obtained after ion exchange chromatography,
제2도는 제1(나)도에서의 7s분획을 SDS-변성 전기영동한 결과이다.Figure 2 is the result of SDS-modified electrophoresis of the 7s fraction in Figure 1 (b).
Claims (5)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1019920014494A KR940003567A (en) | 1992-08-12 | 1992-08-12 | Method for preparing intravenous gamma globulin with immunoglobulins A and M removed |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1019920014494A KR940003567A (en) | 1992-08-12 | 1992-08-12 | Method for preparing intravenous gamma globulin with immunoglobulins A and M removed |
Publications (1)
Publication Number | Publication Date |
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KR940003567A true KR940003567A (en) | 1994-03-12 |
Family
ID=67147308
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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KR1019920014494A KR940003567A (en) | 1992-08-12 | 1992-08-12 | Method for preparing intravenous gamma globulin with immunoglobulins A and M removed |
Country Status (1)
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KR (1) | KR940003567A (en) |
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1992
- 1992-08-12 KR KR1019920014494A patent/KR940003567A/en not_active Application Discontinuation
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