KR930023407A - Process for producing hydrophilic weakly acidic cation exchange resin - Google Patents

Process for producing hydrophilic weakly acidic cation exchange resin Download PDF

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Publication number
KR930023407A
KR930023407A KR1019920008729A KR920008729A KR930023407A KR 930023407 A KR930023407 A KR 930023407A KR 1019920008729 A KR1019920008729 A KR 1019920008729A KR 920008729 A KR920008729 A KR 920008729A KR 930023407 A KR930023407 A KR 930023407A
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KR
South Korea
Prior art keywords
exchange resin
cation exchange
weakly acidic
acidic cation
hydrophilic
Prior art date
Application number
KR1019920008729A
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Korean (ko)
Other versions
KR950011930B1 (en
Inventor
송수석
여규동
위상백
Original Assignee
김상응
주식회사 삼양사
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Publication date
Application filed by 김상응, 주식회사 삼양사 filed Critical 김상응
Priority to KR1019920008729A priority Critical patent/KR950011930B1/en
Publication of KR930023407A publication Critical patent/KR930023407A/en
Application granted granted Critical
Publication of KR950011930B1 publication Critical patent/KR950011930B1/en

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/08—Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/16—Organic material
    • B01J39/18—Macromolecular compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment

Abstract

본 발명은 친수성의 약산성 양이온 교환수지의 제조방법에 관한 것으로서, 더욱 상세하게는 이온 교환 크로마토 그래피에서 단백질등의 생체에 관련된 물질을 분리함에 있어서 단백질에 대한 소수결합에 기인하는 물리적인 흡착이없고, 이온 형에 따른 체적변화가 적은 친수성의 약산성 양이온 교환수지를 제조하는 방법에 관한 것이다.The present invention relates to a method for preparing a hydrophilic weakly acidic cation exchange resin, and more particularly, there is no physical adsorption due to hydrophobic bonding to proteins in separating biologically related substances such as proteins in ion exchange chromatography, The present invention relates to a method for producing a hydrophilic weakly acidic cation exchange resin having a small volume change according to an ion type.

Description

친수성의 약산성 양이온 교환 수지의 제조방법Process for preparing hydrophilic weakly acidic cation exchange resin

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

Claims (4)

이온크로마토 그래피의 분리제로 사용되는 친수성의 약산성 양이온 교환수지를 제조함에 있어서 다음 구조식(Ⅰ)로 표시되는 친수성 모노머를 가교제와 함께 현탁중합하여 얻은 공중합체에 카르복실산을 반응시켜는 것을 특징으로 하는 친수성의 약산성 양이온 교환수지를 제조하는 방법.In preparing a hydrophilic weakly acidic cation exchange resin used as a separation agent for ion chromatography, carboxylic acid is reacted with a copolymer obtained by suspending and polymerizing a hydrophilic monomer represented by the following structural formula (I) together with a crosslinking agent. A method for producing a hydrophilic weakly acidic cation exchange resin. 상기 식에서 R1는 －H 또는 －CH3이다.In the formula, R 1 is -H or -CH 3 . 제1항에 있어서, 상기 가교제로는 에틸렌글리콜 디메티아크릴레이트, 디 또는 트리에틸렌글리콜디메타아크릴레이트, 판테에리트리톨 디 또는 트리메타아크릴레이트, 트리메틸올프로판트리메타아크릴레이트중에서 선택된 하나 또는 둘 이상을 친수성 모노머에 대해 10∼90중량% 반응시키는 것을 특징으로 하는 약산성 양이온 교환수지를 제조하는 방법.The method of claim 1, wherein the crosslinking agent is one or two or more selected from ethylene glycol dimethacrylate, di or triethylene glycol dimethacrylate, pantheritritol di or trimethacrylate, and trimethylolpropane trimethacrylate. A method for producing a weakly acidic cation exchange resin, characterized in that 10 to 90% by weight relative to the hydrophilic monomer. 제1항에 있어서, 상기 카르복실 산으로는 클로로 아세틸산, 또는 푸마릭 산을 공중합체 입자중량에 대해 10∼100중량%로 사용하는 것을 특징으로 하는 친수성의 약산성 양이온 교환수지를 제조하는 방법.The method of claim 1, wherein the carboxylic acid is chloro acetyl acid or fumaric acid is used to prepare a hydrophilic weakly acidic cation exchange resin, characterized in that 10 to 100% by weight based on the copolymer particle weight. 제1항에 있어서, 상기 반응은 30∼90℃의 온도에서 0.1∼24시간 설치하는 것을 특징으로 하는 친수성의 약산성 양이온 교환수지를 제조하는 방법.The method for producing a hydrophilic weakly acidic cation exchange resin according to claim 1, wherein the reaction is performed at a temperature of 30 to 90 캜 for 0.1 to 24 hours. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019920008729A 1992-05-22 1992-05-22 Method for preparing hydrophile weok acidic cation exchange resin KR950011930B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019920008729A KR950011930B1 (en) 1992-05-22 1992-05-22 Method for preparing hydrophile weok acidic cation exchange resin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019920008729A KR950011930B1 (en) 1992-05-22 1992-05-22 Method for preparing hydrophile weok acidic cation exchange resin

Publications (2)

Publication Number Publication Date
KR930023407A true KR930023407A (en) 1993-12-18
KR950011930B1 KR950011930B1 (en) 1995-10-12

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Application Number Title Priority Date Filing Date
KR1019920008729A KR950011930B1 (en) 1992-05-22 1992-05-22 Method for preparing hydrophile weok acidic cation exchange resin

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KR950011930B1 (en) 1995-10-12

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