KR930009587A - Hair growth promoter - Google Patents

Hair growth promoter Download PDF

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Publication number
KR930009587A
KR930009587A KR1019910019591A KR910019591A KR930009587A KR 930009587 A KR930009587 A KR 930009587A KR 1019910019591 A KR1019910019591 A KR 1019910019591A KR 910019591 A KR910019591 A KR 910019591A KR 930009587 A KR930009587 A KR 930009587A
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KR
South Korea
Prior art keywords
hair growth
carbon atoms
hair
general formula
formula
Prior art date
Application number
KR1019910019591A
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Korean (ko)
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KR950006062B1 (en
Inventor
이상국
하병조
문성준
Original Assignee
한동근
태평양화학 주식회사
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Application filed by 한동근, 태평양화학 주식회사 filed Critical 한동근
Priority to KR1019910019591A priority Critical patent/KR950006062B1/en
Publication of KR930009587A publication Critical patent/KR930009587A/en
Application granted granted Critical
Publication of KR950006062B1 publication Critical patent/KR950006062B1/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof

Abstract

본 발명은 신규의 모발생장 촉진제에 관한 것으로, 특히 하기 식(Ⅰ)The present invention relates to a novel hair growth promoter, in particular the following formula (I)

[Y-NH(CH2)nR1R2R3](Q)- (I)[Y-NH (CH 2 ) n R 1 R 2 R 3 ] (Q)-(I)

(상기 식에서, Q는 클로라이드, 브로마이드, 아이오다이드, 포스페이트, 설포네이트, 아세테이트, 락테이트이고, R1, R2, R3는 서로 같거나 다른 탄소수 4내의 이하인 저급 알킬 혹은 알케닐이며, Y는 탄소수 16개 이하의 아미노알킬, 탄소수 2내지 4개의 이하의 알카노일, 벤조일, 수소원자이고, n은 2내지 4의 정수이다.)의 일반식(I : 아미노콜린 유도체)으로 표현되는 화합물 또는 그염을 함유하는 모발 생장 촉진제로서, 이와 같은 촉진제는 탈모에 우수한 양모, 육모 효과를 나타낸다.Wherein Q is chloride, bromide, iodide, phosphate, sulfonate, acetate, lactate, and R 1 , R 2 , R 3 are lower alkyl or alkenyl of up to 4 carbon atoms which are the same or different from each other, Y Is an aminoalkyl having 16 or less carbon atoms, an alkanoyl having 2 to 4 carbon atoms, benzoyl, a hydrogen atom, and n is an integer of 2 to 4), or a compound represented by the general formula (I: aminocholine derivative). As a hair growth promoter containing the salt, such accelerators exhibit excellent wool and hair growth effects for hair loss.

Description

모발 생장 촉진제Hair growth promoter

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

제1도는 본 발명의 모발 생장 촉진제의 세포 생장 촉진 시험의 결과를 나타낸 그래프이다.1 is a graph showing the results of the cell growth promoting test of the hair growth promoter of the present invention.

Claims (5)

하기 일반식 (I)로 표현되는 화합물 또는 그염을 유효 성분으로 함유하는 것을 특징으로 하는 모발생장 촉진재.A hair growth promoting material comprising the compound represented by the following general formula (I) or a salt thereof as an active ingredient. [Y-NH(CH2)nR1R2R3]+(Q)- (1)[Y-NH (CH 2 ) n R 1 R 2 R 3 ] + (Q)-(1) [일반식(I)에서 Q는 클로라이드, 브로마이드, 아이오다이드, 포스페이트, 설포네이트, 아세테이트, 락테이트등이 음이온을 나타내고 R1, R2, R3는 서로 같거나 다른 탄소수4개 이하인 저급 알킬 혹은 알케닐을 나타내고 Y는 탄소수16개 이하의 아미노알킬, 탄소수 2내지 4개 이하의 알카노일, 벤조일, 수소원자를 나타내고 n은 2내지4개의 정수를나타낸다.][In Formula (I), Q represents an anion where chloride, bromide, iodide, phosphate, sulfonate, acetate, lactate, etc., and R 1 , R 2 , R 3 are the same or different lower alkyl having 4 or less carbon atoms. Or alkenyl, Y represents aminoalkyl having 16 or less carbon atoms, alkanoyl, benzoyl, hydrogen atom having 2 to 4 carbon atoms, n represents 2 to 4 integers.] 제1항에 있어서, 다음 일반식(2)로 표현되는 화합물을 유효성분으로 함유하는 것을 특징으로 하는 모발생장 촉진제.The hair growth promoting agent according to claim 1, which contains a compound represented by the following general formula (2) as an active ingredient. [Z-NH3(CH2)nNR1R2R3]+(Q)-(2)[Z-NH 3 (CH 2 ) nNR 1 R 2 R 3 ] + (Q) - (2) [일반식(2)에서 Z는 벤조일 혹은 아세틸을 나타내고, R1, R2, R3, Q 및 n은 상기 제1항에서 정의한 바와 같다.[In General Formula (2), Z represents benzoyl or acetyl, and R 1 , R 2 , R 3 , Q and n are as defined in claim 1 above. 제1항에 있어서, 다음 일반식(3)으로 표현되는 화합물을 유효 성분으로 함유하는 것을 특징으로 하는 모발 생장 촉진제.The hair growth promoter according to claim 1, which contains as an active ingredient a compound represented by the following general formula (3). [Z-NH3(CH2)nNR1R2R3]+(Q)-(3I)[Z-NH 3 (CH 2 ) nNR 1 R 2 R 3 ] + (Q) - (3I) [일반식(3)에서 Q1은 강무지산의 음이온으로 클로라이드, 브로마이드, 아이오다이드를 나타내고 R1, R2, R3, Q 및 n은 상기 제1항에서 정의한 바와 같다.][In formula (3), Q 1 represents an chloride of bromide acid and represents chloride, bromide and iodide, and R 1 , R 2 , R 3 , Q and n are as defined in claim 1 above.] 제1항에 있어서, 헤어토닉, 헤어크림, 헤어로션의 제형임을 특징으로 하는 모발생장 촉진제.According to claim 1, Hair growth promoting agent, characterized in that the formulation of hair tonic, hair cream, hair lotion. 제4항에 있어서, 일반식(I)의 화합물 또는 그염을 0.1내지 1.0%농도로 함유함을 특징으로 하는 모발생장 촉진제.5. The hair growth promoting agent according to claim 4, wherein the compound of formula (I) or a salt thereof is contained at a concentration of 0.1 to 1.0%. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019910019591A 1991-11-05 1991-11-05 Hair growing agent KR950006062B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019910019591A KR950006062B1 (en) 1991-11-05 1991-11-05 Hair growing agent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019910019591A KR950006062B1 (en) 1991-11-05 1991-11-05 Hair growing agent

Publications (2)

Publication Number Publication Date
KR930009587A true KR930009587A (en) 1993-06-21
KR950006062B1 KR950006062B1 (en) 1995-06-08

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ID=19322300

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019910019591A KR950006062B1 (en) 1991-11-05 1991-11-05 Hair growing agent

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Country Link
KR (1) KR950006062B1 (en)

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Publication number Publication date
KR950006062B1 (en) 1995-06-08

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