KR920007620A - Method for dissolving silymarin and pharmaceutical or cosmetic composition - Google Patents

Method for dissolving silymarin and pharmaceutical or cosmetic composition Download PDF

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Publication number
KR920007620A
KR920007620A KR1019900016107A KR900016107A KR920007620A KR 920007620 A KR920007620 A KR 920007620A KR 1019900016107 A KR1019900016107 A KR 1019900016107A KR 900016107 A KR900016107 A KR 900016107A KR 920007620 A KR920007620 A KR 920007620A
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KR
South Korea
Prior art keywords
silymarin
pharmaceutical
cosmetic composition
dissolving
nonionic surfactant
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KR1019900016107A
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Korean (ko)
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KR960009405B1 (en
Inventor
크리빠 펠리세
Original Assignee
다리오 브나꼬르시
인데나 에스. 피. 아
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Application filed by 다리오 브나꼬르시, 인데나 에스. 피. 아 filed Critical 다리오 브나꼬르시
Priority to KR90016107A priority Critical patent/KR960009405B1/en
Publication of KR920007620A publication Critical patent/KR920007620A/en
Application granted granted Critical
Publication of KR960009405B1 publication Critical patent/KR960009405B1/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)

Abstract

내용 없음No content

Description

실리마린 및 약학 또는 화장품조성물이 용해방법Method of dissolving silymarin and pharmaceutical or cosmetic composition

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음As this is a public information case, the full text was not included.

Claims (7)

비이온 계면활성제중의 실리마린분산액을 완전히 용해될 때까지 가열한 후 얻어진 용액을 약학부형제를 선택적으로 함유하는 수용액에 첨가하여 이루어지는 것을 특징으로 하는 실라마린의 용해방법.A method for dissolving silamarin, characterized in that the solution obtained by heating the silymarin dispersion in a nonionic surfactant until complete dissolution is added to an aqueous solution optionally containing a pharmaceutical excipient. 제1항에 있어서, 상기 비이온 계면활성제가 폴리옥실-40-수소처리된 피마자유 및 올레일알코올의 폴리에틸렌-20-글리콜 에테르로부터 선택되는 것을 특징으로 하는 실리마린의 용해방법.The method of claim 1 wherein the nonionic surfactant is selected from polyoxyl-40-hydrogenated castor oil and polyethylene-20-glycol ethers of oleyl alcohol. 제1항 또는 제2항에 있어서, 상기 비이온 계면 활성제가 글리콜과 결합되는 것을 특징으로 하는 실리마린의 용해방법.The method for dissolving silymarin according to claim 1 or 2, wherein the nonionic surfactant is combined with glycol. 제1항 또는 제2항에 있어서, 상기 실리마린 대 계면활성제 비가 1:4 내지 1:25인 것을 특징으로 하는 실리마린의 용해방법.The method of claim 1 or 2, wherein the silymarin to surfactant ratio is 1: 4 to 1:25. 제3항에 있어서, 상기 실리마린 대 계면활성제 비가 1:4 내지 1:25인 것을 특징으로 하는 실리마린의 용해방법.The method of claim 3 wherein the silymarin to surfactant ratio is from 1: 4 to 1:25. 제1항 내지 제4항의 방법에 의해 용해된 실리마린의 활성성분으로서 함유하는 것을 특징으로 하는 약학 또는 화장품 조성물.A pharmaceutical or cosmetic composition comprising as an active ingredient of silymarin dissolved by the method of claims 1 to 4. 제6항에 있어서, 상기 약학 또는 화장품 조성물이 가용성 경구제제 또는 피부의학용 겔의 형태로 존재하는 것을 특징으로 하는 약학 또는 화장품 조성물.The pharmaceutical or cosmetic composition according to claim 6, wherein the pharmaceutical or cosmetic composition is in the form of a soluble oral preparation or a dermatological gel. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR90016107A 1990-10-11 1990-10-11 Process for the dissolution of silymarin KR960009405B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR90016107A KR960009405B1 (en) 1990-10-11 1990-10-11 Process for the dissolution of silymarin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR90016107A KR960009405B1 (en) 1990-10-11 1990-10-11 Process for the dissolution of silymarin

Publications (2)

Publication Number Publication Date
KR920007620A true KR920007620A (en) 1992-05-27
KR960009405B1 KR960009405B1 (en) 1996-07-19

Family

ID=19304517

Family Applications (1)

Application Number Title Priority Date Filing Date
KR90016107A KR960009405B1 (en) 1990-10-11 1990-10-11 Process for the dissolution of silymarin

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KR (1) KR960009405B1 (en)

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Publication number Publication date
KR960009405B1 (en) 1996-07-19

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