KR910019952A - Separation and Purification Method of Eicosapentaenoic Acid and Its Ester - Google Patents

Separation and Purification Method of Eicosapentaenoic Acid and Its Ester Download PDF

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Publication number
KR910019952A
KR910019952A KR1019900007747A KR900007747A KR910019952A KR 910019952 A KR910019952 A KR 910019952A KR 1019900007747 A KR1019900007747 A KR 1019900007747A KR 900007747 A KR900007747 A KR 900007747A KR 910019952 A KR910019952 A KR 910019952A
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KR
South Korea
Prior art keywords
eicosapentaenoic acid
separation
carbon atoms
purification method
ester
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Application number
KR1019900007747A
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Korean (ko)
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KR920003777B1 (en
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김영학
임건빈
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이상운
고려합섬 주식회사
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Priority to KR1019900007747A priority Critical patent/KR920003777B1/en
Publication of KR910019952A publication Critical patent/KR910019952A/en
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Publication of KR920003777B1 publication Critical patent/KR920003777B1/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/03—Monocarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C7/00—Purification; Separation; Use of additives
    • C07C7/12—Purification; Separation; Use of additives by adsorption, i.e. purification or separation of hydrocarbons with the aid of solids, e.g. with ion-exchangers

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Water Supply & Treatment (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fats And Perfumes (AREA)

Abstract

내용 없음No content

Description

에이코사펜타엔산과 그 에스테르의 분리정제 방법Separation and Purification Method of Eicosapentaenoic Acid and Its Ester

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

제1도는 본 발명의 실시예에서 사용한 원료에 대한 가스크로마토그람이고, 제2도는 상기 실시예에서의 분취용 액체크로마토그람이며, 제3도는 본 발명의 실시예에 따라 분리정제한 가스크로마토프람이다.1 is a gas chromatogram for the raw material used in the embodiment of the present invention, FIG. 2 is a preparative liquid chromatogram in the above embodiment, and FIG. 3 is a gas chromatogram separated and purified according to the embodiment of the present invention. .

Claims (3)

에이코사펜타엔산을 함유하고 있는 지방산 알킬에스테르 혼합물로부터 액체크로마토그라피에 의해 에이코사펜타엔산을 분리 정제함에 있어서, 칼럼충전제로서 8~24개의 탄소수를 가진 알킬리가 실리카에 화학 결합된 것을 사용하고, 용리액으로서 극성 단일 용매를 사용하여서 됨을 특징으로 하는 에이코사펜타엔산과 그 에스테르의 분리정제 방법In the separation and purification of eicosapentaenoic acid by liquid chromatography from a fatty acid alkyl ester mixture containing eicosapentaenoic acid, an alkylli having 8 to 24 carbon atoms as a column filler is chemically bonded to silica. Separation and purification method of eicosapentaenoic acid and its esters, characterized by using a polar single solvent as eluent 제1항에 있어서, 상기 탄소수8~28개의 알킬기는 상기 충전재 전체에 대해 5~30중량%로 실리카에 화학 결합되어 있은 것을 특징으로 하는 에이코사펜타엔산과 그 에스테르의 분리정제 방법The method of claim 1, wherein the alkyl group having 8 to 28 carbon atoms is chemically bonded to silica at 5 to 30% by weight based on the entire filler. 제1항에 있어서, 상기 극성단일 용매로서는 탄소수1~4개의 저급 알코올을 사용하는 것을 특징으로 하는 에이코사펜타엔산과 그 에스테르의 분리정제 방법The method for separating and purifying eicosapentaenoic acid and esters thereof according to claim 1, wherein lower polar alcohols having 1 to 4 carbon atoms are used as the polar monosolvent. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019900007747A 1990-05-29 1990-05-29 Separating method of eicosapentanoic acid and their ester KR920003777B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019900007747A KR920003777B1 (en) 1990-05-29 1990-05-29 Separating method of eicosapentanoic acid and their ester

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019900007747A KR920003777B1 (en) 1990-05-29 1990-05-29 Separating method of eicosapentanoic acid and their ester

Publications (2)

Publication Number Publication Date
KR910019952A true KR910019952A (en) 1991-12-19
KR920003777B1 KR920003777B1 (en) 1992-05-14

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KR1019900007747A KR920003777B1 (en) 1990-05-29 1990-05-29 Separating method of eicosapentanoic acid and their ester

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Publication number Publication date
KR920003777B1 (en) 1992-05-14

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