KR910018018A - Stable tablet containing alkylcysteine or acid addition salts thereof - Google Patents

Stable tablet containing alkylcysteine or acid addition salts thereof Download PDF

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Publication number
KR910018018A
KR910018018A KR1019900005599A KR900005599A KR910018018A KR 910018018 A KR910018018 A KR 910018018A KR 1019900005599 A KR1019900005599 A KR 1019900005599A KR 900005599 A KR900005599 A KR 900005599A KR 910018018 A KR910018018 A KR 910018018A
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KR
South Korea
Prior art keywords
tablet
acid addition
addition salt
nucleated
binder solution
Prior art date
Application number
KR1019900005599A
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Korean (ko)
Other versions
KR920006901B1 (en
Inventor
도모히로 하야시다
가쓰미 아끼요시
기꾸마루 가도야
Original Assignee
하기하라 후미오
요시또미세이야꾸 가부시끼가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by 하기하라 후미오, 요시또미세이야꾸 가부시끼가이샤 filed Critical 하기하라 후미오
Priority to KR1019900005599A priority Critical patent/KR920006901B1/en
Publication of KR910018018A publication Critical patent/KR910018018A/en
Application granted granted Critical
Publication of KR920006901B1 publication Critical patent/KR920006901B1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids

Abstract

내용 없음No content

Description

알킬시스테인 또는 그 산부가염을 함유하는 안정한 정제Stable tablet containing alkylcysteine or acid addition salts thereof

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

Claims (5)

결합제 용액을 제립한 일킬시스테인 또는 그의 산부가염에 활택제를 혼합하고 , 압축성형하여 수득한 알킬 시스테인 또는 그의 산부가염을 함유하는 안정한 정제.A stable tablet containing an alkyl cysteine or an acid addition salt thereof obtained by mixing a lubricant with ilkycysteine or an acid addition salt thereof having a binder solution and compression molding. 장용성 피막을 입힌 제1항의 정제를 핵정으로하여 이루어진 유핵정.A nucleus tablet made of the tablet of claim 1 coated with an enteric coating. 제1또는 2항에 있어서, 결합제 용액이 메틸셀률로우스, 히드록시프로필셀룰로우스 히드록시프로필메틸셀룰로우스, 에틸릴셀룰로우스, 히드록시프로필메틸셀룰로우스 프탈레이트, 카르복시메틸 에틸셀룰로우스 및 메타아크릴산 코폴리머로 이루어진 군에서 선택된 1종 이상이 겨합제 또는 코팅제를 메탄올, 에탄올, 이소프로필알콜, 에틸아세테이트, 메틸렌클로라이드, 디클로로에탄, 트리클로로에탄, 시클로헥, n-헥산으로 이루어진 군에서 선택된 1종또는 2종 이상의 혼합물을 주성분으로 하는 용매에 용해한 용액인 것을 특징으로하는 정제 또는 유핵정.The binder solution of claim 1 or 2, wherein the binder solution is methylcellulose, hydroxypropylcellulose hydroxypropylmethylcellulose, ethylylcellulose, hydroxypropylmethylcellulose phthalate, carboxymethyl ethylcellulose. At least one copolymer or coating agent selected from the group consisting of U.S. and methacrylic acid copolymers includes methanol, ethanol, isopropyl alcohol, ethyl acetate, methylene chloride, dichloroethane, trichloroethane, cyclohex and n-hexane. A tablet or nucleated tablet characterized in that it is a solution dissolved in a solvent composed mainly of one or two or more kinds selected from. 제1또는 2항에 있어서, 활택제가 마그네슘 스테아레이트, 칼슘 스테아레이트, 스테아린산, 수소첨가식물유, 산처리탈크, 경질 무수규산으로 이루어진 군에서 선택된 1종또는 2종 이상의 혼합물인 것을 특징으로 하는 정제 또는 유핵정.The method of claim 1 or 2, wherein the lubricant is one or a mixture of two or more selected from the group consisting of magnesium stearate, calcium stearate, stearic acid, hydrogenated vegetable oil, acid treated talc and light silicic anhydride. Nucleated tablets. 제1 내지 4항중 어느 한항에 있어서, 알킬시스테인 또는 그의 산부가염이 염산메틸시스테인 또는 염산L-에틸시스테인인 것을 특징으로 하는 정제 또는 유핵정.The tablet or nucleated tablet according to any one of claims 1 to 4, wherein the alkyl cysteine or an acid addition salt thereof is methyl cysteine hydrochloride or L-ethyl cysteine hydrochloride. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019900005599A 1990-04-20 1990-04-20 Stable tablet containing alkylcystein or its salt KR920006901B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019900005599A KR920006901B1 (en) 1990-04-20 1990-04-20 Stable tablet containing alkylcystein or its salt

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019900005599A KR920006901B1 (en) 1990-04-20 1990-04-20 Stable tablet containing alkylcystein or its salt

Publications (2)

Publication Number Publication Date
KR910018018A true KR910018018A (en) 1991-11-30
KR920006901B1 KR920006901B1 (en) 1992-08-22

Family

ID=19298206

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019900005599A KR920006901B1 (en) 1990-04-20 1990-04-20 Stable tablet containing alkylcystein or its salt

Country Status (1)

Country Link
KR (1) KR920006901B1 (en)

Also Published As

Publication number Publication date
KR920006901B1 (en) 1992-08-22

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