KR910011861A - Novel 2- (thiazol-4-yl) thiazolo [3,2-a)] benzimidazole derivatives - Google Patents

Abstract

No content.

Description

Novel 2- (thiazol-4-yl) thiazolo [3,2-a] benzimidazole derivatives

As this is a public information case, the full text was not included.

Claims (4)

The compound of formula (I) and a pharmacologically acceptable acid addition salt Said general formula, R ₁ and R ₂ are lower alkoxy of each represent a hydrogen atom, C ₁ -C ₄ lower alkyl group, C ₁ -C ₄ lower alkoxy groups, C ₁ -C ₄ of the same or different to each other, a carbonyl group, an amine group , A C ₁ -C ₄ lower alkylamine group, a carboxyl group, a cyan group, a nitro group, an amido group, and a group selected from a halogen atom, R ₃ is a hydrogen atom or a lower alkyl group of C ₁ -C ₄ , R ₄ is a C ₁ -C ₄ lower alkyl group, an aryl group, an amine group, a C ₁ -C ₄ lower alkylamine group, an arylamino group, a hydrazine group, or an aminoimino methyleneamino (guanidine) group. 2. A compound according to claim 1, wherein R ₁ and R ₂ are hydrogen atoms, C ₁ -C ₄ lower alkyl groups, C ₁ -C ₄ lower alkoxy groups, C ₁ -C ₄ lower alkoxy carbonyl groups, amine groups, carboxyl groups and nitros A group selected from the group consisting of a group, an amido group and a halogen atom, R ₃ is a hydrogen atom or a methyl or ethyl group, and R ₄ is an amine group, a monosubstituted C ₁ -C ₄ lower alkylamine group, or a guanidine group Compounds and pharmacologically acceptable acid addition salts. According to claim 2, wherein, R ₁ and R ₂ are hydrogen atoms, C ₁ -C ₄ lower alkyl group, a lower alkoxycarbonyl group, a carboxyl group, an amine group, an amino lower alkoxy group of _{C 1 -C 4, C 1 -C} 4 A compound selected from the group consisting of pottery and halogen atoms, and R ₃ is a hydrogen atom or a methyl group, R ₄ is an amine group, methylamine group, ethylamine group, propylamine group, butylamine group, or guanidine group Permissible acid addition salts. A method for producing formula (I), wherein the compound of formula (II) is reacted with the compound of formula (III). In the above general formula, R ₁ and R ₂ are the same or different from each other, and each hydrogen atom, lower alkyl group, lower alkoxy carbonyl group, alkoxy group, amine group, lower alkylamine group, carboxyl group, cyan group, nitro group, amido group, and halogen a group selected from the group consisting of reactor configuration, R ₃ is a lower alkyl group, a hydrogen atom or a C ₁ -C _4, R ₄ is a C ₁ -C ₄ lower alkyl group, an aryl group, an amine group, a lower C ₁ -C ₄ Alkylamine group, hydrazine group, or guanidine group. ※ Note: The disclosure is based on the initial application.