KR900011448A - How to Use Retinoids to Treat or Prevent Naturally Aged Skin - Google Patents

How to Use Retinoids to Treat or Prevent Naturally Aged Skin Download PDF

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Publication number
KR900011448A
KR900011448A KR1019900000603A KR900000603A KR900011448A KR 900011448 A KR900011448 A KR 900011448A KR 1019900000603 A KR1019900000603 A KR 1019900000603A KR 900000603 A KR900000603 A KR 900000603A KR 900011448 A KR900011448 A KR 900011448A
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KR
South Korea
Prior art keywords
retinoid
aged skin
treat
naturally aged
tetramethyl
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KR1019900000603A
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Korean (ko)
Inventor
엠. 클리그만 알버트
에이. 메직 제임스
제이. 카페톨라 로버트
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원본미기재
오프토 파마슈티칼 코포레이션
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Publication of KR900011448A publication Critical patent/KR900011448A/en

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Abstract

내용 없음No content

Description

레티노이드를 사용하여 자연적으로 노화된 피부를 치료 또는 예방하는 방법.How to treat or prevent naturally aged skin using retinoids.

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음As this is a public information case, the full text was not included.

제1도는 암컷 알비노 무노(Skh-1)마우스에 비히클 또는 모두-트랜스-레티노산을 수면기간동안 적용시킨 결과의 사진이다. 제2도는 80주된 정상 노 마우스의 사진이다.(H＆E염색). 제3도는 85주된 크림 비히클처린된 마우스의 사진이다.FIG. 1 is a photograph of the results of applying vehicle or all-trans-retinoic acid to female Albino muno (Skh-1) mice during sleep. Figure 2 is a photograph of a normal 80-week-old normal mouse (H & E staining). Figure 3 is a photograph of an 85 week cream vehicle treated mouse.

Claims (6)

유효량의 레티노이드를 약제학적으로 허용되는 담체와 함께 국소투여 함을 특징으로 하여, 자연적으로 노화된피부를 치료 또는 예방하는 방법.A method for treating or preventing naturally aged skin, characterized by topically administering an effective amount of retinoid with a pharmaceutically acceptable carrier. 제1항에 있어서, 레티노이드가 모두 -트랜스-레티노산인 방법.The method of claim 1, wherein the retinoids are all -trans-retinoic acid. 제1항에 있어서, 레티노이드가 13-시스-레티노산인 방법.The method of claim 1 wherein the retinoid is 13-cis-retinoic acid. 제1항에 있어서, 레티노이드가 레티놀인 방법.The method of claim 1 wherein the retinoid is retinol. 제1항에 있어서, 레티노이드가 (E)-4-[4-메틸-6-(2,6,6-트리메틸-1-사이클로헥센-1-일)-1,3,5-헥사트리에닐] 벤조산, (E)-6-[2-(4-에틸설포닐)페닐]-1-메틸에테닐]-1,2,3,4-테트라하이드로-1,1,4,4-테트라메틸나프탈렌, 4-[(5,6,7,8-테르하이드로-5,5,8,8-테트라메틸-2-나프탈레닐,에티닐]벤조산, 및(E)-4-[2-(5,6,7,8-테트라하이드로-7-하이드록시-5,5,8,8-테트라메틸-2-나프탈레닐)-1-프로페닐]벤질 알코올로 이루어진 그룹중에서 선택되는방법.The method of claim 1, wherein the retinoid is (E) -4- [4-methyl-6- (2,6,6-trimethyl-1-cyclohexen-1-yl) -1,3,5-hexatrienyl ] Benzoic acid, (E) -6- [2- (4-ethylsulfonyl) phenyl] -1-methylethenyl] -1,2,3,4-tetrahydro-1,1,4,4-tetramethyl Naphthalene, 4-[(5,6,7,8-terhydro-5,5,8,8-tetramethyl-2-naphthalenyl, ethynyl] benzoic acid, and (E) -4- [2- ( 5,6,7,8-tetrahydro-7-hydroxy-5,5,8,8-tetramethyl-2-naphthalenyl) -1-propenyl] benzyl alcohol. 제1항에 있어서, 레티노이드가 약0.00001 중량% 내지 0.2중량%의 양으로 존재하는 방법.The method of claim 1 wherein the retinoid is present in an amount from about 0.00001% to 0.2% by weight. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019900000603A 1989-01-19 1990-01-19 How to Use Retinoids to Treat or Prevent Naturally Aged Skin KR900011448A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US29911989A 1989-01-19 1989-01-19
US299,119 1989-01-19
US58883589A 1989-01-20 1989-01-20
US588,835 1989-01-20

Publications (1)

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KR900011448A true KR900011448A (en) 1990-08-01

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KR1019900000603A KR900011448A (en) 1989-01-19 1990-01-19 How to Use Retinoids to Treat or Prevent Naturally Aged Skin

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KR (1) KR900011448A (en)

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