KR890016012A - Method for preparing 2,4-dihydroxyquinoline derivative - Google Patents

Method for preparing 2,4-dihydroxyquinoline derivative Download PDF

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Publication number
KR890016012A
KR890016012A KR1019880003822A KR880003822A KR890016012A KR 890016012 A KR890016012 A KR 890016012A KR 1019880003822 A KR1019880003822 A KR 1019880003822A KR 880003822 A KR880003822 A KR 880003822A KR 890016012 A KR890016012 A KR 890016012A
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KR
South Korea
Prior art keywords
polyphosphoric acid
preparing
dihydroxyquinoline
prepared
general formula
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Application number
KR1019880003822A
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Korean (ko)
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KR950014791B1 (en
Inventor
나오시 이마끼
유끼 다꾸마
마리 오이시
Original Assignee
망요 미쓰오
미쓰비시 케미칼 인더스트리스 리미티드
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Priority to KR1019880003822A priority Critical patent/KR950014791B1/en
Publication of KR890016012A publication Critical patent/KR890016012A/en
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Publication of KR950014791B1 publication Critical patent/KR950014791B1/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4

Abstract

내용 없음No content

Description

2,4-디히드록시퀴놀린 유도체의 제조방법Method for preparing 2,4-dihydroxyquinoline derivative

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

Claims (3)

하기 일반식(Ⅰ)의 아릴 말론산 아미드 에스테르 유도체를 다중인산을 사용하여 고리화 반응시키는 것으로 구성되는 하기 일반식(Ⅱ)의 2,4-디히드록시퀴놀린 유도체 및 그의 토오토머의 제조방법.Method for producing 2,4-dihydroxyquinoline derivatives of the following general formula (II) consisting of cyclization reaction of aryl malonic acid amide ester derivatives of the following general formula (I) using polyphosphoric acid . 상기식에서, R1,R2,R3및 R4가 수소원자, 저급 알킬기, 저급 알콕시기 또는 할로겐 원자이고 ; 또 R5는 저급 알킬기임.Wherein R 1 , R 2 , R 3 and R 4 are hydrogen atoms, lower alkyl groups, lower alkoxy groups or halogen atoms; And R 5 is a lower alkyl group. 제 1 항에 있어서, 다중인산을 0.2 내지 2.0 범위내의 P2O5/H3PO4몰 비율로 제조한 방법.The process of claim 1 wherein the polyphosphoric acid is prepared in a P 2 O 5 / H 3 PO 4 molar ratio in the range of 0.2 to 2.0. 제 1 항에 있어서, 다중인산을 0.4 내지 0.6범위내의 P2O5/H3PO4몰 비율로 제조한 방법.The method of claim 1, wherein the polyphosphoric acid is prepared at a molar ratio of P 2 O 5 / H 3 PO 4 in the range of 0.4 to 0.6. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019880003822A 1988-04-04 1988-04-04 Process for preparing 2,4-dihydroxyquinoline deriontives KR950014791B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019880003822A KR950014791B1 (en) 1988-04-04 1988-04-04 Process for preparing 2,4-dihydroxyquinoline deriontives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019880003822A KR950014791B1 (en) 1988-04-04 1988-04-04 Process for preparing 2,4-dihydroxyquinoline deriontives

Publications (2)

Publication Number Publication Date
KR890016012A true KR890016012A (en) 1989-11-27
KR950014791B1 KR950014791B1 (en) 1995-12-14

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Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019880003822A KR950014791B1 (en) 1988-04-04 1988-04-04 Process for preparing 2,4-dihydroxyquinoline deriontives

Country Status (1)

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KR (1) KR950014791B1 (en)

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Publication number Publication date
KR950014791B1 (en) 1995-12-14

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