KR890003741A - 7- (1-pyrrolidinyl) quinolonecarboxylic acid derivative - Google Patents

7- (1-pyrrolidinyl) quinolonecarboxylic acid derivative Download PDF

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Publication number
KR890003741A
KR890003741A KR1019870008575A KR870008575A KR890003741A KR 890003741 A KR890003741 A KR 890003741A KR 1019870008575 A KR1019870008575 A KR 1019870008575A KR 870008575 A KR870008575 A KR 870008575A KR 890003741 A KR890003741 A KR 890003741A
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South Korea
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group
hydroxyl
methyl
silver
hydrogen
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KR1019870008575A
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Korean (ko)
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KR890005200B1 (en
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페터센 우베
그로에 클라우스
자일러 한스-요아힘
게오르그 메쯔거 칼
Original Assignee
클라우스 데너, 귄터 슈마커
바이엘 악티엔게젤샤프트
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Priority to KR1019870008575A priority Critical patent/KR890005200B1/en
Publication of KR890003741A publication Critical patent/KR890003741A/en
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Abstract

내용 없음No content

Description

7-(1-피롤리디닐)퀴놀론카르복실산 유도체7- (1-pyrrolidinyl) quinolonecarboxylic acid derivative

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

Claims (4)

하기 일반식(Ⅰ)으로 표시되는 7-(1-피롤리디닐)-3-퀴놀론카르복실산 유도체 및 그의 제약상 사용 가능한 수화물 및 모 카르복실산의 알칼리 금속, 알칼리토금속, 은 및 구아니딘 염류.Alkali metal, alkaline earth metal, silver and guanidine salts of 7- (1-pyrrolidinyl) -3-quinolonecarboxylic acid derivative represented by the following general formula (I) and pharmaceutically usable hydrates and parent carboxylic acids thereof. 상기 식중 A는 CH, CCI, CF 또는 N이고, R1은 히드록실, 히드록시메틸 또는 메르캅토기이고, R2은 수소, 알킬(탄소원자수 1 내지 4개) 또는 (5-메틸-2-옥소-1,3-디옥솔-4-일)메틸기이되, 단 R1이 히디록실기인 경우에는 A는 CF 또는 N기가 될 수 없다.Wherein A is CH, CCI, CF or N, R 1 is hydroxyl, hydroxymethyl or mercapto group, R 2 is hydrogen, alkyl (1-4 carbon atoms) or (5-methyl-2- Oxo-1,3-dioxol-4-yl) methyl, provided that when R 1 is a hydroxyl group, A cannot be a CF or N group. 제1항에 있어서, A가, CH, CCI, CF 또는 N이고, R1이 히드록실, 히드록시메닐 또는 미르캅토기이고, R2가 수소, 메틸, 에틸, 프로필 또는 이소프로필기이되, 단 R1이 히드록실기인 경우에 A는 CF 또는 N기가 될 수 없는 일반식(Ⅰ)의 화합물 및 그의 제약상 사용가능한 수화물 및 모 카르복실산의 알칼리 금속, 알칼리토 금속, 은 및 구아니딘 염류.The compound of claim 1, wherein A is CH, CCI, CF or N, R 1 is a hydroxyl, hydroxymenyl or mircapto group, and R 2 is a hydrogen, methyl, ethyl, propyl or isopropyl group, provided that When R 1 is a hydroxyl group A is a compound of formula (I) which cannot be a CF or N group and its pharmaceutically usable hydrates and alkali metal, alkaline earth metal, silver and guanidine salts of the parent carboxylic acid. 제1항에 있어서, A가, CH, CCI 또는 CF이고, R2가 히드록실 또는 히드록시메틸기이고, R2가 수소, 메틸, 또는 에틸기이되, 단 R1이 히드록실기인 경우에 A는 CF기가 될 수 없는 화합물 및 그의 제약상 사용가능한 수화물 및 모 카르복실산과의 알칼리 금속, 알칼리토 금속, 은 및 구아니딘 염류.The method of claim 1, wherein when A is, CH, the CCI or CF, and, R 2 is a hydroxyl or hydroxymethyl group, and, R 2 is hydrogen, methyl, or being etilgiyi, with the proviso that R 1 is a hydroxyl group A is Alkali metal, alkaline earth metal, silver and guanidine salts with a compound which cannot be a CF group and its pharmaceutically usable hydrates and parent carboxylic acids. 인체 또는 동물 치료 용도의 하기 일반식(Ⅰ)으로 표시되는 7-(1-피롤리디닐)-3-퀴놀론카르복실산 유도체 및 그의 제약상 사용가능한 수화물 및 모 카르복실산으 알칼리 금속, 알칼리토금속, 은 및 구아니딘 염류.7- (1-pyrrolidinyl) -3-quinolonecarboxylic acid derivative represented by the following general formula (I) for human or animal therapeutic use, and its pharmaceutically usable hydrates and alkali carboxylic acid as the parent carboxylic acid, Silver and guanidine salts. 상기 식중 A는 CH,CCl,CF 또는 N이고, R1은 히드록실, 히드록시메틸 또는 메르캅토기이고, R2는 수소, 알킬(탄소원자수 1 내지 4개) 또느 (5-메틸-2-옥소-1,3-디옥솔-4-일)메틸기이되, 단 R1이 히드록실기인 경우에는 A는 CF 또는 N기가 될 수 없다.Wherein A is CH, CCl, CF or N, R 1 is hydroxyl, hydroxymethyl or mercapto group, R 2 is hydrogen, alkyl (1-4 carbon atoms) or (5-methyl-2- Oxo-1,3-dioxol-4-yl) methyl, provided that when R 1 is a hydroxyl group, A cannot be a CF or N group. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019870008575A 1987-08-05 1987-08-05 7-(1-pyrrolidinyl) quinoline carboxylic-acid derivatives KR890005200B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019870008575A KR890005200B1 (en) 1987-08-05 1987-08-05 7-(1-pyrrolidinyl) quinoline carboxylic-acid derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019870008575A KR890005200B1 (en) 1987-08-05 1987-08-05 7-(1-pyrrolidinyl) quinoline carboxylic-acid derivatives

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KR890003741A true KR890003741A (en) 1989-04-17
KR890005200B1 KR890005200B1 (en) 1989-12-18

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100351503B1 (en) * 2000-06-07 2002-09-05 학교법인고려중앙학원 A chicken snack using spent fowl meat and process for preparation thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100351503B1 (en) * 2000-06-07 2002-09-05 학교법인고려중앙학원 A chicken snack using spent fowl meat and process for preparation thereof

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KR890005200B1 (en) 1989-12-18

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