Claims (2)
하기 일반식 (I)의 브라시노라이드 유사체 :Brassinolide analogs of general formula (I)
상기식에서 R은 탄소수 1~10의 지방족 또는 시클로기, 1~3개의 치환체(여기서 치환체는 저급 알킬기, 저급 알케닐기임)를 가져도 좋은 방향족기, 1~3개의 치환체(여기서 치환체는 저급알킬기, 저급 알케틸기임)를 가져도 좋은 복수환기를 나타내며, 탄소22위치와 R사이에 0~3개의 탄소수를 가질 수 있다.Wherein R is an aliphatic or cyclo group having 1 to 10 carbon atoms, an aromatic group which may have 1 to 3 substituents (wherein the substituents are lower alkyl groups and lower alkenyl groups), 1 to 3 substituents (where the substituents are lower alkyl groups, A lower alketyl group), which may have a plural ring group, and may have 0 to 3 carbon atoms between the carbon 22 position and R.
제 1 항에 있어서, 브라시노 유사체가 2α,3α-디히드록시-20-(1-히드록시아밀)-5α-프레그난-6-온, 2α,3α-디히드록시-20-(1-히드록시헥실)-5α-프레그난-6-온, 2α,3α-디히드록시-20-{(1-히드록시이소아밀)메틸}-5α-프레그난-6-온, 2α,3α-디히드록시-20-{(1-히드록시-1-이소헵틸)메틸}-5α-프레그난-6-온, 2α,3α-디히드록시-20-[1-히드록시-1-(2-피코일)]메틸-5α-프레그난-6-온, 2α,3α-디히드록시-20-{1-히드옥시-1-(5-메틸-2-피코일)}메틸-5α-프레그난-6-온, 2α,3α-디히드록시-20-{(1-히드록시-2-티오페닐)에틸}-5α-프레그난-6-온,2α,3α-디히드록시-20-{(1-히드록시-2-푸라닐)에틸}-5α-프레그난-6-온, 2α,3α-디히드록시-20-[1-히드록시-1-(2-피코일)]메틸-5α-프레그난-6-온, 2α,3α-디히드록시-20-{1-히드록시-1-(3-피코일)}메틸-5α-프레그난-6온, 2α,3α-디히드록시-20-{1-히드록시-1-(4-피코일)}메틸-5α-프레그난-6-온, 2α,3α-디히드록시-20-(1-히드록시프로필)-5α-프레그난-6-온, 2α,3α-디히드록시-20-(1-히드록시부틸)-5α-프레그난-6-온, 2α,3α-디히드록시-20-{(1-히드록시-2-페닐)에틸}-5α-프레그난-6-온,2α,3α-디히드록시-20-(1-히드록시-1-페닐메틸)-5α-프레그난-6-온인 화합물.The method of claim 1 wherein the brassino analog is 2α, 3α-dihydroxy-20- (1-hydroxyamyl) -5α-pregnan-6-one, 2α, 3α-dihydroxy-20- (1- Hydroxyhexyl) -5α-pregnan-6-one, 2α, 3α-dihydroxy-20-{(1-hydroxyisoamyl) methyl} -5α-pregnan-6-one, 2α, 3α-di Hydroxy-20-{(1-hydroxy-1-isoheptyl) methyl} -5α-pregnan-6-one, 2α, 3α-dihydroxy-20- [1-hydroxy-1- (2- Picoyl)] methyl-5α-pregnan-6-one, 2α, 3α-dihydroxy-20- {1-hydroxyoxy-1- (5-methyl-2-picoyl)} methyl-5α-pregnane -6-one, 2α, 3α-dihydroxy-20-{(1-hydroxy-2-thiophenyl) ethyl} -5α-pregnan-6-one, 2α, 3α-dihydroxy-20- { (1-hydroxy-2-furanyl) ethyl} -5α-pregnan-6-one, 2α, 3α-dihydroxy-20- [1-hydroxy-1- (2-phycoyl)] methyl- 5α-Pregnan-6-one, 2α, 3α-dihydroxy-20- {1-hydroxy-1- (3-phycoyl)} methyl-5α-pregnan-6-one, 2α, 3α-dihydrate Hydroxy-20- {1-hydroxy-1- (4-phycoyl)} methyl-5α-pre L-6-one, 2α, 3α-dihydroxy-20- (1-hydroxypropyl) -5α-pregnan-6-one, 2α, 3α-dihydroxy-20- (1-hydroxybutyl) -5α-pregnan-6-one, 2α, 3α-dihydroxy-20-{(1-hydroxy-2-phenyl) ethyl} -5α-pregnan-6-one, 2α, 3α-dihydroxy -20- (1-hydroxy-1-phenylmethyl) -5α-pregnan-6-one.
※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.