KR880013894A - Method for preparing 2,6-di lower alkyl-4-substitutedphenyl-1,4-dihydropyridine-3,5-dicarboxylic acid ester derivative - Google Patents

Method for preparing 2,6-di lower alkyl-4-substitutedphenyl-1,4-dihydropyridine-3,5-dicarboxylic acid ester derivative Download PDF

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KR880013894A
KR880013894A KR870005463A KR870005463A KR880013894A KR 880013894 A KR880013894 A KR 880013894A KR 870005463 A KR870005463 A KR 870005463A KR 870005463 A KR870005463 A KR 870005463A KR 880013894 A KR880013894 A KR 880013894A
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South Korea
Prior art keywords
lower alkyl
structural formula
following structural
substituted
group
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KR870005463A
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Korean (ko)
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김완주
심영기
유성은
이상희
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최영복
재단법인 한국화학연구소
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Priority to KR870005463A priority Critical patent/KR880013894A/en
Publication of KR880013894A publication Critical patent/KR880013894A/en

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Abstract

내용 없음No content

Description

2, 6-디저급알킬-4-치환페닐-1, 4-디하이드로피리딘-3, 5-디카르복실산 에스테르 유도체의 제조방법Method for preparing 2,6-di loweralkyl-4-substitutedphenyl-1, 4-dihydropyridine-3, 5-dicarboxylic acid ester derivative

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

Claims (1)

다음 구조식(Ⅱ)로 표시되는 벤즈알데하이드 유도체와 다음 구조식(Ⅲ)으로 표시되는 아미노 크로토네이트 알킬 에스테르 및 다음 구조식(Ⅳ)로 표시되는 저급알카노일 초산아미노 알킬에스테를 동시에 반응시키거나, 또는 임의의 순서대로 반응시키는 것을 특징으로 하는 다음 구조식(Ⅰ)로 표시되는 2, 6-디저급알킬-4-치환페닐-1, 4-디하이드로피리딘-3, 5-디카르복실산 에스테르 유도체의 제조방법.Benzaldehyde derivatives represented by the following structural formula (II), amino crotonate alkyl esters represented by the following structural formula (III) and lower alkanoyl acetate amino alkyl esters represented by the following structural formula (IV) are reacted simultaneously, or optionally Preparation of 2, 6-di lower alkyl-4- substituted phenyl- 1, 4-dihydropyridine-3, 5-dicarboxylic acid ester derivative represented by following Structural formula (I) characterized by reacting in order of Way. 상기 구조식(Ⅰ), (Ⅱ), (Ⅲ) 및 (Ⅳ)에서, R은 수소원자이거나 저급알킬기, R1과 R2는 저급알킬기, R3는 치환 혹은 비치환된 알킬기 또는 아릴알킬기, R4는 치환 혹은 비치환된 알킬기 또는 아미노 아릴알킬기, 그리고 R5는 페닐기에 대하여 오르토-, 메타-, 또는 파라- 위치에 치환될 수 있는 할로겐기, 니트로기, 트리플루오르메틸기 또는 저급알콕시기를 나타낸다.In the above formulas (I), (II), (III) and (IV), R is a hydrogen atom or a lower alkyl group, R 1 and R 2 are lower alkyl groups, R 3 is a substituted or unsubstituted alkyl group or an arylalkyl group, R 4 represents a substituted or unsubstituted alkyl or amino arylalkyl group, and R 5 represents a halogen, nitro, trifluoromethyl or lower alkoxy group which may be substituted in the ortho-, meta- or para- position relative to the phenyl group. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR870005463A 1987-05-30 1987-05-30 Method for preparing 2,6-di lower alkyl-4-substitutedphenyl-1,4-dihydropyridine-3,5-dicarboxylic acid ester derivative KR880013894A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR870005463A KR880013894A (en) 1987-05-30 1987-05-30 Method for preparing 2,6-di lower alkyl-4-substitutedphenyl-1,4-dihydropyridine-3,5-dicarboxylic acid ester derivative

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Application Number Priority Date Filing Date Title
KR870005463A KR880013894A (en) 1987-05-30 1987-05-30 Method for preparing 2,6-di lower alkyl-4-substitutedphenyl-1,4-dihydropyridine-3,5-dicarboxylic acid ester derivative

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KR880013894A true KR880013894A (en) 1988-12-22

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KR870005463A KR880013894A (en) 1987-05-30 1987-05-30 Method for preparing 2,6-di lower alkyl-4-substitutedphenyl-1,4-dihydropyridine-3,5-dicarboxylic acid ester derivative

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