KR880012237A - Method for preparing thrombin formulation - Google Patents

Method for preparing thrombin formulation Download PDF

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Publication number
KR880012237A
KR880012237A KR870003790A KR870003790A KR880012237A KR 880012237 A KR880012237 A KR 880012237A KR 870003790 A KR870003790 A KR 870003790A KR 870003790 A KR870003790 A KR 870003790A KR 880012237 A KR880012237 A KR 880012237A
Authority
KR
South Korea
Prior art keywords
added
preparing thrombin
thrombin formulation
preparing
prothrombin
Prior art date
Application number
KR870003790A
Other languages
Korean (ko)
Other versions
KR890002070B1 (en
Inventor
박영일
Original Assignee
유성락
이연합성약품공업 주식회사
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 유성락, 이연합성약품공업 주식회사 filed Critical 유성락
Priority to KR1019870003790A priority Critical patent/KR890002070B1/en
Publication of KR880012237A publication Critical patent/KR880012237A/en
Application granted granted Critical
Publication of KR890002070B1 publication Critical patent/KR890002070B1/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue

Abstract

내용 없음No content

Description

트롬빈 제제의 제조방법Method for preparing thrombin formulation

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

Claims (1)

소의 혈액에 수산나트륨을 가하여 분리한 혈장에 황산바륨을 가하여 프로트롬빈을 흡착시킨 후 구연산나트륨으로 용출시키고 여기에 소의 뇌에서 추출한 트롬보프라스틴을 가하여 프로트롬빈을 트롬빈으로 활성화시킨 다음 황산암모늄으로 분획화하여 트롬빈 제제를 제조하는 방법.Sodium hydroxide was added to bovine blood and barium sulfate was added to adsorbed plasma to adsorb prothrombin, eluted with sodium citrate, and thromboprastin extracted from bovine brain was added to activate prothrombin with thrombin and fractionated with ammonium sulfate. Method for preparing thrombin formulations. ※ 참고사항 : 최초출원내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019870003790A 1987-04-21 1987-04-21 Process for preparing thrombins KR890002070B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019870003790A KR890002070B1 (en) 1987-04-21 1987-04-21 Process for preparing thrombins

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019870003790A KR890002070B1 (en) 1987-04-21 1987-04-21 Process for preparing thrombins

Publications (2)

Publication Number Publication Date
KR880012237A true KR880012237A (en) 1988-11-26
KR890002070B1 KR890002070B1 (en) 1989-06-16

Family

ID=19260854

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019870003790A KR890002070B1 (en) 1987-04-21 1987-04-21 Process for preparing thrombins

Country Status (1)

Country Link
KR (1) KR890002070B1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3808841A1 (en) * 2015-02-06 2021-04-21 Guangzhou Bioseal Biotech Co., Ltd. Method for preparation of thrombin

Also Published As

Publication number Publication date
KR890002070B1 (en) 1989-06-16

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