KR880001634A - Pyroglutamide derivative manufacturing method - Google Patents

Pyroglutamide derivative manufacturing method Download PDF

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Publication number
KR880001634A
KR880001634A KR1019870006950A KR870006950A KR880001634A KR 880001634 A KR880001634 A KR 880001634A KR 1019870006950 A KR1019870006950 A KR 1019870006950A KR 870006950 A KR870006950 A KR 870006950A KR 880001634 A KR880001634 A KR 880001634A
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KR
South Korea
Prior art keywords
pyroglutamide
following general
general formula
reacting
derivative manufacturing
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KR1019870006950A
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Korean (ko)
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KR950013764B1 (en
Inventor
키요시 기무리
마사히로 키세
쇼오이찌 죠까이
켄이찌 나까무라
Original Assignee
모리시다 히로시
닛본신야꾸 가부시기 가이샤
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Application filed by 모리시다 히로시, 닛본신야꾸 가부시기 가이샤 filed Critical 모리시다 히로시
Publication of KR880001634A publication Critical patent/KR880001634A/en
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Publication of KR950013764B1 publication Critical patent/KR950013764B1/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Abstract

내용 없음No content

Description

피로글루타미드 유도체 및 제조방법Pyroglutamide Derivatives and Preparation Methods

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음As this is a public information case, the full text was not included.

Claims (3)

다음 일반식[I]로 표시되는 D-피로글루타미드 유도체D-pyroglutamide derivative represented by the following general formula [I] D-피로글루타민산 또는 그 반응성유도체에 피페리딘을 반응시키는 것을 특징으로 하는 다음의 일반식[I]로 표시되는 D-피로글로타미드 유도체의 제조방법.A process for producing a D-pyroglotamide derivative represented by the following general formula [I] characterized by reacting piperidine with D-pyroglutamic acid or a reactive derivative thereof. D-피로글르타민산과 하기식(V)의 화합물과 축합제를 반응시키고, 생성된 에스테르에 피페리딘을 반응시키는 것을 특징으로 하는 다음의 일반식[I]로 표시되는 D-피로글루타미드 유도체의 제조방법.D-pyroglutamide represented by the following general formula [I] characterized by reacting D-pyroglutamic acid with a compound of the formula (V) and a condensing agent and reacting piperidine with the produced ester. Process for the preparation of derivatives. 상기식에서 R은 알콜류 또는 페놀류의 잔기.R is a residue of an alcohol or a phenol. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019870006950A 1986-07-24 1987-07-01 Pyroglutamide derivatives, method of preparing them and antidementia composition containing them KR950013764B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP???61-175168 1986-07-24
JP17516886 1986-07-24
JP175168 1986-07-24

Publications (2)

Publication Number Publication Date
KR880001634A true KR880001634A (en) 1988-04-25
KR950013764B1 KR950013764B1 (en) 1995-11-15

Family

ID=15991451

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019870006950A KR950013764B1 (en) 1986-07-24 1987-07-01 Pyroglutamide derivatives, method of preparing them and antidementia composition containing them

Country Status (2)

Country Link
JP (1) JPS63146857A (en)
KR (1) KR950013764B1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998018469A1 (en) * 1996-10-31 1998-05-07 Nippon Shinyaku Co., Ltd. Cranial nerve cell protectives

Also Published As

Publication number Publication date
JPS63146857A (en) 1988-06-18
KR950013764B1 (en) 1995-11-15

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