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C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
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Organic Chemistry
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Organic Low-Molecular-Weight Compounds And Preparation Thereof
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Abstract
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Description
아세틸디카르니틴 디클로라이드의 제조 방법Method for preparing acetyldicarnitine dichloride
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.
Claims (1)
아세틸 카르니틴 클로라이드 및 즉시 증류한 티오닐 클로라이드, 1:1.5 몰비의 혼합물을 실온에서 0.5 내지 2시간 동안 교반시키고, 과잉 티오닐 클로-라이드를 제거한 후, 생성되는 아실클로라이드를 메틸렌클로라이드에 용해시키고, 여기에 동량의 카르니틴 클로라이드를 가하여 생성되는 혼합물38°내지 42℃의 온도로 18 내지 36시간 동안 유지시켜 조생성물을 수득한 다음, 이 조생성물을 뜨거운 이소프로필 알코올에 용해시킨 후 결정화시킴을 특징으로 하는, 하기 구조식(Ⅰ)의 아세틸디카르니틴 디클로라이드의 제조 방법.A mixture of acetyl carnitine chloride and immediately distilled thionyl chloride, 1: 1.5 molar ratio, was stirred at room temperature for 0.5 to 2 hours, excess thionyl chloride was removed, and the resulting acylchloride was dissolved in methylene chloride, To a mixture obtained by adding an equal amount of carnitine chloride to a temperature of 38 ° to 42 ° C. for 18 to 36 hours to obtain a crude product, which is then dissolved in hot isopropyl alcohol and crystallized. , Method for producing acetyldicarnitine dichloride of formula (I).※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019850007149A1985-09-271985-09-27Method of producing acetyldicarnitine dichloride
KR930009822B1
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