KR860007258A - Method for preparing imidazo [4,5-C] pyridine - Google Patents

Method for preparing imidazo [4,5-C] pyridine Download PDF

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Publication number
KR860007258A
KR860007258A KR1019860002289A KR860002289A KR860007258A KR 860007258 A KR860007258 A KR 860007258A KR 1019860002289 A KR1019860002289 A KR 1019860002289A KR 860002289 A KR860002289 A KR 860002289A KR 860007258 A KR860007258 A KR 860007258A
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KR
South Korea
Prior art keywords
pyridine
methoxy
imidazo
preparing
diaminopyridine
Prior art date
Application number
KR1019860002289A
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Korean (ko)
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KR870000930B1 (en
Inventor
마이클 그린 제임스
앤 고드 제인
Original Assignee
메리 앤 터커
일라이 릴리앤드 캄파니
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Publication of KR860007258A publication Critical patent/KR860007258A/en
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Publication of KR870000930B1 publication Critical patent/KR870000930B1/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Abstract

The present invention provides a process for preparing 2-[2-methoxy-4-(methylthio)phenyl]-1(3)H-imidazo[4,5-c]pyridine comprising reacting 3,4-diaminopyridine with 2-methoxy-4-methylthiobenzoic acid in the presence of phosphorus oxychloride and pyridine.

Description

이미다조[4,5-C] 피리딘의 제조방법Method for preparing imidazo [4,5-C] pyridine

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

Claims (3)

3,4-디아미노피리딘을 포스포러스옥시 클로라이드 및 피리딘 존재하 약 25℃내지 약 125℃의 온도에서 2-메톡시-4-메틸티오 벤조산과 반응시킴을 특징으로 하여, 구조식(Ⅰ)또는(Ⅰa)의 2-[2-메톡시-4-(메틸티오)페닐]-1(3) H-이미다조[4,5-C]피리딘을 제조하는 방법.3,4-diaminopyridine is reacted with 2-methoxy-4-methylthio benzoic acid at a temperature of about 25 ° C to about 125 ° C in the presence of phosphorusoxy chloride and pyridine, A process for preparing 2- [2-methoxy-4- (methylthio) phenyl] -1 (3) H-imidazo [4,5-C] pyridine of IA). 제 1 항에 있어서, 반응을 약 50℃ 내지 약 80℃의 온도에서 수행하는 방법.The process of claim 1 wherein the reaction is carried out at a temperature of about 50 ° C. to about 80 ° C. 6. 제 1 항에 있어서, 약동몰량의 3,4-디아미노피리딘 및 2-메톡시-4-메틸티오벤조산을 사용하는 방법.The process according to claim 1, wherein about equimolar amounts of 3,4-diaminopyridine and 2-methoxy-4-methylthiobenzoic acid are used. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR8602289A 1985-03-29 1986-03-27 Process for preparing inotropic imidazo (4,s-c)pyridine KR870000930B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71800085A 1985-03-29 1985-03-29
US718000 1985-03-29

Publications (2)

Publication Number Publication Date
KR860007258A true KR860007258A (en) 1986-10-10
KR870000930B1 KR870000930B1 (en) 1987-05-11

Family

ID=24884411

Family Applications (1)

Application Number Title Priority Date Filing Date
KR8602289A KR870000930B1 (en) 1985-03-29 1986-03-27 Process for preparing inotropic imidazo (4,s-c)pyridine

Country Status (8)

Country Link
EP (1) EP0196224B1 (en)
JP (1) JPS61229878A (en)
KR (1) KR870000930B1 (en)
AT (1) ATE45578T1 (en)
CA (1) CA1295330C (en)
DE (1) DE3665064D1 (en)
HU (1) HU195219B (en)
IL (1) IL78241A0 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5322672B2 (en) * 2008-11-28 2013-10-23 住友化学株式会社 Method for producing dibenzooxepin compound
IL272141B1 (en) 2017-07-27 2024-03-01 Adocia Compositions in the form of an injectable aqueous solution comprising at least human insulin a21g and a prandial action glucagon suppressor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3273461D1 (en) * 1981-08-19 1986-10-30 Merck Patent Gmbh 2-arylimidazopyridines
ES8401486A1 (en) * 1981-11-10 1983-12-01 Wellcome Found New imidazo[4,5-c]pyridine derivatives, processes for their preparation and pharmaceutical formulations containing such compounds.
ZA832938B (en) * 1982-05-03 1984-12-24 Lilly Co Eli 2-phenylimidazo(4,5-c)pyridines

Also Published As

Publication number Publication date
EP0196224B1 (en) 1989-08-16
EP0196224A1 (en) 1986-10-01
IL78241A0 (en) 1986-07-31
CA1295330C (en) 1992-02-04
JPS61229878A (en) 1986-10-14
KR870000930B1 (en) 1987-05-11
DE3665064D1 (en) 1989-09-21
HU195219B (en) 1988-04-28
ATE45578T1 (en) 1989-09-15
HUT40655A (en) 1987-01-28

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