KR850007984A - Method for preparing 6-amino peniclanic acid by cell immobilization - Google Patents

Method for preparing 6-amino peniclanic acid by cell immobilization Download PDF

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Publication number
KR850007984A
KR850007984A KR1019840002814A KR840002814A KR850007984A KR 850007984 A KR850007984 A KR 850007984A KR 1019840002814 A KR1019840002814 A KR 1019840002814A KR 840002814 A KR840002814 A KR 840002814A KR 850007984 A KR850007984 A KR 850007984A
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KR
South Korea
Prior art keywords
acid
producing
preparing
aminophenicylanic
alginic acid
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KR1019840002814A
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Korean (ko)
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KR860000699B1 (en
Inventor
정교민
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신동관
태평양화학공업 주식회사
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Priority to KR1019840002814A priority Critical patent/KR860000699B1/en
Publication of KR850007984A publication Critical patent/KR850007984A/en
Application granted granted Critical
Publication of KR860000699B1 publication Critical patent/KR860000699B1/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P37/00—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin
    • C12P37/06—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin by desacylation of the substituent in the 6 position

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)

Abstract

내용 없음No content

Description

균체 고정화에 의한 6-아미노 페니실란산의 제조방법Method for preparing 6-amino peniclanic acid by cell immobilization

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음As this is a public information case, the full text was not included.

Claims (3)

페니실린 지아실라제를 대량 생산하는 미생물균주를 공지의 방법으로 배양하여 얻은 미생물 균체 현탁액과 소듐알긴산 용액을 혼합하여 염화칼슘용액에 적하시켜 구슬상의 고경화 균체를 제조하여 이 고경화 균체를 이용하여 회분법이나, 컬럼법으로 6-아미노페니실란산을 제조하는 균체 고경화에 의한 6-아미노페니실란산의 제 조방법.A microbial cell suspension that produces large amounts of penicillin giacylase is cultured by a known method, mixed with a microbial cell suspension and sodium alginic acid solution, and added to calcium chloride solution to prepare a bead-shaped hardened cell. A method for producing 6-aminophenicylanic acid by cell hardening for producing 6-aminophenicylanic acid by column method. 제1항에 있어서, 고경화 균체를 제조할 때, 소듐알긴산의 농도 범위를 1-5%로 하는 균체 고경화에 의한 6-아미노페니실란산의 제조방법.The method for producing 6-aminophenicylanic acid according to claim 1, wherein when producing the highly cured cells, the concentration of sodium alginic acid is 1-5%. 제1항에 있어서, 고경화 균체를 제조할 때, 소듐알긴산과 배양된 미생물 균체의 혼합액을 0.01-0.1몰 범위의 염화칼슘 용액에 적하하는 균체 고경화에 의한 6아미노페니실란산의 제조방법.The method for preparing 6-aminophenic silane acid according to claim 1, wherein the mixed solution of sodium alginic acid and the cultured microbial cells is added dropwise to a calcium chloride solution in the range of 0.01-0.1 mole when the high-cured cells are prepared. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019840002814A 1984-05-23 1984-05-23 Process for preparing 6-amino penicillanic acid by using immobilized microorganism KR860000699B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019840002814A KR860000699B1 (en) 1984-05-23 1984-05-23 Process for preparing 6-amino penicillanic acid by using immobilized microorganism

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019840002814A KR860000699B1 (en) 1984-05-23 1984-05-23 Process for preparing 6-amino penicillanic acid by using immobilized microorganism

Publications (2)

Publication Number Publication Date
KR850007984A true KR850007984A (en) 1985-12-11
KR860000699B1 KR860000699B1 (en) 1986-06-07

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ID=19233936

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019840002814A KR860000699B1 (en) 1984-05-23 1984-05-23 Process for preparing 6-amino penicillanic acid by using immobilized microorganism

Country Status (1)

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Publication number Publication date
KR860000699B1 (en) 1986-06-07

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