KR850005823A - Process for preparing 1- (4-chlorobenzoyl) -5-methoxy-2-methyl-3-indole acetate ester - Google Patents

Process for preparing 1- (4-chlorobenzoyl) -5-methoxy-2-methyl-3-indole acetate ester Download PDF

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Publication number
KR850005823A
KR850005823A KR1019840000616A KR840000616A KR850005823A KR 850005823 A KR850005823 A KR 850005823A KR 1019840000616 A KR1019840000616 A KR 1019840000616A KR 840000616 A KR840000616 A KR 840000616A KR 850005823 A KR850005823 A KR 850005823A
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South Korea
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group
methyl
groups
chlorobenzoyl
methoxy
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KR1019840000616A
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Korean (ko)
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KR860001024B1 (en
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서정진(외2)
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박춘거
주식회사 유한양행
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  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

내용 없음No content

Description

1-(4-클로로벤조일)-5-메톡시-2-메칠-3-인돌초산에스테르의 제조방법Process for preparing 1- (4-chlorobenzoyl) -5-methoxy-2-methyl-3-indole acetate ester

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음As this is a public information case, the full text was not included.

Claims (1)

구조식(Ⅲ)으로 표시되는 1-(4-클로로벤조일)-5-메톡시-2-메칠-3-인돌초산과 하기 구조식(Ⅳ)의 치올을 반응시켜 치올에스케르(Ⅱ)를 중간체로 얻고 여기에 아콜을 부가함을 특징으로 하여 구조식(Ⅰ)화합물을 제조하는 방법.1- (4-chlorobenzoyl) -5-methoxy-2-methyl-3-indoleacetic acid represented by Structural Formula (III) is reacted with a thiol of Structural Formula (IV) to obtain a thiol escher (II) as an intermediate. A method for producing a compound of formula (I), characterized by the addition of acol. 상기 구조식에서 R은 알킬기, 알케닐기, 알콕시알킬기, 치환아릴기아릴기, 아릴알킬기 및 사이클로 알킬기를 나타낸다.In the above structural formula, R represents an alkyl group, alkenyl group, alkoxyalkyl group, substituted aryl group aryl group, arylalkyl group and cycloalkyl group. 또 치올의 R'는 탄소수 1-5개를 갖는 알킬기, 알킬잔기내에 3개미만의 탄소수를 갖는 페닐알킬기, 페닐기, 모노 또는 디 치환페닐기, 나프틸기 아일기 및 복소환기이다.R 'of the thiol is an alkyl group having 1 to 5 carbon atoms, a phenylalkyl group having less than 3 carbon atoms in the alkyl residue, a phenyl group, a mono or di-substituted phenyl group, a naphthyl group isyl group and a heterocyclic group. 가능한 복소환기는 피리딘기, 5-(2-메칠-1,3,4-티아디아졸)기, 5-(1-메칠-테트라졸)기, 4-(1,2,3-트리아졸)기 등이다.Possible heterocyclic groups are pyridine groups, 5- (2-methyl-1,3,4-thiadiazole) groups, 5- (1-methyl-tetrazol) groups, 4- (1,2,3-triazole) And so on. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019840000616A 1984-02-10 1984-02-10 Process for preparing 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-3-indol acetic acid esters KR860001024B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019840000616A KR860001024B1 (en) 1984-02-10 1984-02-10 Process for preparing 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-3-indol acetic acid esters

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019840000616A KR860001024B1 (en) 1984-02-10 1984-02-10 Process for preparing 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-3-indol acetic acid esters

Publications (2)

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KR850005823A true KR850005823A (en) 1985-09-26
KR860001024B1 KR860001024B1 (en) 1986-07-28

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KR1019840000616A KR860001024B1 (en) 1984-02-10 1984-02-10 Process for preparing 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-3-indol acetic acid esters

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KR860001024B1 (en) 1986-07-28

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