KR850001195A - Method for preparing carbostyryl derivative - Google Patents

Method for preparing carbostyryl derivative Download PDF

Info

Publication number
KR850001195A
KR850001195A KR1019830001818A KR830001818A KR850001195A KR 850001195 A KR850001195 A KR 850001195A KR 1019830001818 A KR1019830001818 A KR 1019830001818A KR 830001818 A KR830001818 A KR 830001818A KR 850001195 A KR850001195 A KR 850001195A
Authority
KR
South Korea
Prior art keywords
group
carbon atoms
general formula
following general
alkyl group
Prior art date
Application number
KR1019830001818A
Other languages
Korean (ko)
Other versions
KR830002909B1 (en
Inventor
가즈오(외 3) 사까노
Original Assignee
오오쓰까 아끼히꼬
오오쓰까세이야꾸 가부시끼가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 오오쓰까 아끼히꼬, 오오쓰까세이야꾸 가부시끼가이샤 filed Critical 오오쓰까 아끼히꼬
Priority to KR1019830001818A priority Critical patent/KR830002909B1/en
Application granted granted Critical
Publication of KR830002909B1 publication Critical patent/KR830002909B1/en
Publication of KR850001195A publication Critical patent/KR850001195A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)

Abstract

내용 없음No content

Description

카르보스티릴 유도체의 제조방법Method for preparing carbostyryl derivative

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음As this is a public information case, the full text was not included.

Claims (1)

하기 일반식(16)의 화합물을 하기 일반식(17) 또는 하기 일반식(18)이나 하기 일반식(19)과 반응시키거나 하기 일반식(20)과 반응시킴을 특징으로 하는 하기 일반식(1)의 카르보스티릴 유도체의 제조방법.A compound of the following general formula (16) is reacted with the following general formula (17), the following general formula (18) or the following general formula (19), or the following general formula (20) Method for producing a carbostyryl derivative of 1). 상기식에서,In the above formula, R1은 수소원자, 1∼6개의 탄소원자를 갖는 알킬기, 2∼4개의 탄소원자를 갖는 알케닐기, 2∼4개의 탄소원자를 갖는 알키닐기, 1∼4개의 탄소원자를 갖는 알킬렌기를 갖는 페닐알킬기를 나타내며, R2는 수소원자, 1∼4개의 탄소원자를 갖는 알킬기 또는 페닐기를 나타내며, R3는 수소원자, 히드록시기 또는 1∼4개의 탄소원자를 갖는 알킬기, 1∼4개의 탄소원자를 갖는 알카노일옥시기, 또는 3,4,5-트리메톡시벤조일옥시기를 나타내며, R4는 수소원자 또는 1∼4개의 탄소원자를 갖는 알킬기를 나타내며, X는 할로겐 원자를 나타내며, n은 0 또는 1또는 2의 정수를 나타내며, Q는 2 또는 3의 정수를 나타내며, ℓ과 m은 각각 0 또는 1∼6개의 정수를 나타내나 ℓ과 m의 합이 6을 초과할 수 없으며, B는 1∼4개의 탄소원자 또는 치환체로서 페닐기 또는 1∼4개의 탄소원자를 갖는 알카노일옥시기를 갖는 치환알킬기, 3∼8개의 탄소원자를 갖는 시클로알킬기, 1∼4개의 탄소원자를 갖는 알카노일기, 벤조일기, 또는 일반식(식중, R12는 할로겐원자, 1∼4개의 탄소원자를 갖는 알킬 또는 1∼4개의 탄소원자를 갖는 알콕시기를 나타내며, q는 0 또는 1∼2의 정수임)을 나타내고, 카르보스티릴 골격중 3- 및 4-위치 사이의 탄소-탄소결합은 단일 결합이거나 이중결합을 나타내며, 일반식R 1 represents a hydrogen atom, an alkyl group having 1 to 6 carbon atoms, an alkenyl group having 2 to 4 carbon atoms, an alkynyl group having 2 to 4 carbon atoms, a phenylalkyl group having an alkylene group having 1 to 4 carbon atoms R 2 represents a hydrogen atom, an alkyl group having 1 to 4 carbon atoms or a phenyl group, R 3 represents a hydrogen atom, a hydroxy group or an alkyl group having 1 to 4 carbon atoms, an alkanoyloxy group having 1 to 4 carbon atoms, or Represents a 3,4,5-trimethoxybenzoyloxy group, R 4 represents a hydrogen atom or an alkyl group having from 1 to 4 carbon atoms, X represents a halogen atom, n represents an integer of 0 or 1 or 2, Q represents an integer of 2 or 3, l and m represent 0 or 1 to 6 integers, respectively, but the sum of l and m cannot exceed 6, and B is a phenyl group as 1 to 4 carbon atoms or substituents. Or 1 to 4 carbon atoms Substituted alkyl group having an alkanoyloxy group having, cycloalkyl group having 3 to 8 carbon atoms, alkanoyl group having 1 to 4 carbon atoms, benzoyl group, or general formula (Wherein R 12 represents a halogen atom, an alkyl having 1 to 4 carbon atoms or an alkoxy group having 1 to 4 carbon atoms, q is an integer of 0 or 1 to 2), and 3- and 2 in the carbostyryl skeleton Carbon-carbon bonds between 4-positions represent single bonds or double bonds 의 측쇄의 치환위치는 카르보스티릴 골격중 4-, 5-, 6-, 7- 또는 8-위치의 어느 하나이며, 일반식The substitution position of the side chain of is any of 4-, 5-, 6-, 7- or 8-position of the carbostyryl skeleton, and 의 측쇄의 치환위치는 카르보스티릴 골격중 4-, 5-, 6-, 7- 또는 8-위치의 어느 하나이며, R10은 치환체로서, 1∼4개의 탄소원자, 페닐기 또는 1∼4개의 탄소원자를 알카노일옥시기를 갖는 알킬기, 3∼8개의 탄소원자를 갖는 시클로알킬기를 나타내며, R6는 수소원자, 히드록시기 또는 1∼4개의 탄소원자를 갖는 알킬기를 나타내고, R11은 1∼4개의 탄소원자를 갖는 알카노일기 또는 벤조일기를 나타내며, X7,X8및 X9은 각각 할로겐 원자를 나타낸다.The substituted position of the side chain of is any of 4-, 5-, 6-, 7- or 8-position of carbostyryl frame | skeleton, and R <10> is a substituent and has 1-4 carbon atoms, a phenyl group, or 1-4 A carbon atom represents an alkyl group having an alkanoyloxy group, a cycloalkyl group having 3 to 8 carbon atoms, R 6 represents a hydrogen atom, a hydroxy group or an alkyl group having 1 to 4 carbon atoms, and R 11 represents 1 to 4 carbon atoms The alkanoyl group or benzoyl group which has is shown, X <7> , X <8> and X <9> represent a halogen atom, respectively. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019830001818A 1979-03-30 1983-04-28 Process for preparing carboxtyril derivatives KR830002909B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019830001818A KR830002909B1 (en) 1979-03-30 1983-04-28 Process for preparing carboxtyril derivatives

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR7900996A KR820002231B1 (en) 1979-03-30 1979-03-30 Process for preparing novel carbostyril derivatives
KR1019830001818A KR830002909B1 (en) 1979-03-30 1983-04-28 Process for preparing carboxtyril derivatives

Related Parent Applications (2)

Application Number Title Priority Date Filing Date
KR7900996A Division KR820002231B1 (en) 1979-03-30 1979-03-30 Process for preparing novel carbostyril derivatives
KR8204658A Division KR830002910B1 (en) 1979-03-30 1982-10-15 Process for preparing carbostyril derivatives

Publications (2)

Publication Number Publication Date
KR830002909B1 KR830002909B1 (en) 1983-12-30
KR850001195A true KR850001195A (en) 1985-03-16

Family

ID=19211245

Family Applications (4)

Application Number Title Priority Date Filing Date
KR7900996A KR820002231B1 (en) 1979-03-30 1979-03-30 Process for preparing novel carbostyril derivatives
KR8204658A KR830002910B1 (en) 1979-03-30 1982-10-15 Process for preparing carbostyril derivatives
KR1019830001819A KR830002895B1 (en) 1979-03-30 1983-04-28 Process for preparing carbostyril derivatives
KR1019830001818A KR830002909B1 (en) 1979-03-30 1983-04-28 Process for preparing carboxtyril derivatives

Family Applications Before (3)

Application Number Title Priority Date Filing Date
KR7900996A KR820002231B1 (en) 1979-03-30 1979-03-30 Process for preparing novel carbostyril derivatives
KR8204658A KR830002910B1 (en) 1979-03-30 1982-10-15 Process for preparing carbostyril derivatives
KR1019830001819A KR830002895B1 (en) 1979-03-30 1983-04-28 Process for preparing carbostyril derivatives

Country Status (1)

Country Link
KR (4) KR820002231B1 (en)

Also Published As

Publication number Publication date
KR830002910B1 (en) 1983-12-30
KR820002231B1 (en) 1982-12-03
KR850001196A (en) 1985-03-16
KR830002909B1 (en) 1983-12-30
KR830002895B1 (en) 1983-12-30

Similar Documents

Publication Publication Date Title
ES479134A1 (en) Pharmaceutically useful carbostyril derivatives
KR830007486A (en) Preparation of new 2-arylether ether derivatives and thioether derivatives and insecticides, insecticides
KR890002198A (en) Organosilicon compounds
KR870006039A (en) Novel thiazole compound, preparation method thereof and pharmaceutical composition containing the compound
KR830009094A (en) 9- [2- (3-Indolyl) ethyl] -1-oxa-4.9-diazaspiro [5.5] undecane-3-one
ES8200679A1 (en) Carbostyril derivatives, and antihistaminic agents containing the same
KR830001214A (en) 1,2,4,5-tetra-alkyl-4-arylpiperidine
KR840001157A (en) Method for preparing carbostyryl derivative
KR840006983A (en) Method for preparing piperazine derivatives
KR850001195A (en) Method for preparing carbostyryl derivative
KR860002517A (en) Method for preparing tris (β, β-dimethylphenethyl) tin compound
KR920702685A (en) 4,6-O-hydroxyphosphorylglucosamine derivative
KR850005830A (en) Method for preparing 2-alkoxyaminosulfonylbenzene-sulfonylurea
KR850006191A (en) Method for preparing thiocano pyrimidine derivative
KR890004994A (en) New Platinum Complex
KR840002821A (en) Method for preparing N- (2,3-epoxypropylene) -N-aralkylsulfonamide derivative
KR840001578A (en) Process for preparing 9,10-substituted 2-mesitylimino-3-alkyl-3,4,6,7-tetrahydro-2H-pyrimido (6,1-a) isoquinolin-4-one
KR840001144A (en) Method for preparing 5 (6) -phenylsulfonyloxy-benzimidazole derivative
KR920008012A (en) Triazole derivatives
KR840000503A (en) Method for preparing 4-benzoyl-5-hydroxy pyrazole compound
KR910002829A (en) Method for preparing polyalkyl-2-alkoxy-7-hydroxychroman derivative
KR850004098A (en) Method for preparing butanol derivatives
KR830002798A (en) Method for preparing alkyl-ketohex pyranoside derivatives
KR920009882A (en) How to prepare polyester
KR860008184A (en) Preparation of Dioxolobenzoisoxazole Derivatives

Legal Events

Date Code Title Description
A107 Divisional application of patent
G160 Decision to publish patent application
E701 Decision to grant or registration of patent right
GRNT Written decision to grant
FPAY Annual fee payment

Payment date: 19931112

Year of fee payment: 11

EXPY Expiration of term