KR850000982A - Non-carious antibody for treating caries by human streptococcus mutans and method for producing the composition - Google Patents

Non-carious antibody for treating caries by human streptococcus mutans and method for producing the composition Download PDF

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Publication number
KR850000982A
KR850000982A KR1019840004419A KR840004419A KR850000982A KR 850000982 A KR850000982 A KR 850000982A KR 1019840004419 A KR1019840004419 A KR 1019840004419A KR 840004419 A KR840004419 A KR 840004419A KR 850000982 A KR850000982 A KR 850000982A
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South Korea
Prior art keywords
antibody
streptococcus mutans
strain
producing
composition according
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KR1019840004419A
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Korean (ko)
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KR890004123B1 (en
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다가시 쭈루미즈 (외 1)
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미즈노에 고오에이
기다사노 겐큐쇼
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Publication of KR850000982A publication Critical patent/KR850000982A/en
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Publication of KR890004123B1 publication Critical patent/KR890004123B1/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Birds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Cosmetics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Confectionery (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

내용 없음No content

Description

스트렙토콕커스 뮤탄스에 의한 인간의 충치 처치용 비우식성 항체 및 그 조성물의 제조방법Non-carious antibody for treating caries by human streptococcus mutans and method for producing the composition

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

Claims (8)

스트렙토콕커스 뮤탄스 유래의 1종 이상의 항원으로 포유동물을 면역함으로서 상기 동물의 체내에 항체를 산출시켜 이것을 회수하는 공정으로 된 스트렙토콕커스ㆍ 뮤탄스에 의해 유발된 인간의 충치예방 또는 억제용 항체의 제조방법에 있어 상기 1종 이상의 항원에(a) 혈청형 c.e.f. 및/또는 g형 균주유래의 제1항원 및 (b)혈청형 이형 균주유래의 제2항원인 것과 상기항원이 균주세포 표면의 선모상 구조에서 분리되는 것을 특징으로 하는 비우식성 항체의 제조방법.Human caries preventing or inhibiting antibodies caused by Streptococcus mutans, which is a step of producing an antibody in the body of the animal by immunizing the mammal with at least one antigen derived from Streptococcus mutans and recovering it (A) serotype cef to the one or more antigens in the preparation method of And / or a first antigen derived from a g-type strain and (b) a second antigen derived from a serotype heterologous strain, and the antigen is separated from the stem cell structure on the surface of the strain cell. 상기 1항에 있어 상기 균주가 변이주인 상기의 제조방법.The method according to claim 1, wherein the strain is a mutant strain. 상기 1항의 방법에 의해 제조된 종이상의 항체의 유효량을 가식성 담체 또는 부형제에 공종시키는 공정에서 되는 스트렙토콕커스 ㆍ뮤탄스에 유발된 인간의 충치를 억제하기 위한 비우식성 조성물의 제조방법.A method for producing a non-carious composition for suppressing human caries caused by Streptococcus mutans, which is subjected to a step of co-expressing an effective amount of an antibody on a paper produced by the method of claim 1 to an edible carrier or an excipient. 상기 3항에 있어 상기 적어도 하나의 항체는 각각 첫번째 및 두번째 항체가 모두 상기 제1 및 제2의 항원에 상응하는 상기의 방법.The method of claim 3, wherein the at least one antibody each corresponds to both the first and second antigens. 상기 3항에 있어 츄잉껌, 캔디, 아이스크림, 또는 드롭프스로서 형성된 것에 의한 상기 조성물.The composition according to claim 3, formed as chewing gum, candy, ice cream, or drops. 상기 3항에 있어 시럽, 쥬-스, 소프트드링크 또는 요쿠르트로서 형성시킨 것에 의한 상기 조성물.The composition according to claim 3, which is formed as a syrup, juice, soft drink or yogurt. 상기 3항에 있어 치마제 또는 구강세척제로서 형성시킨 것에 의한 상기의 조성물.The composition according to claim 3, which is formed as a dentifrice or mouthwash. 상기 3항에 있어 밧갈스, 트로치로서 형성된 것에 의한 상기의 조성물.The composition according to claim 3, which is formed as bagels or troches. ※참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: It is to be disclosed based on the initial application.
KR1019840004419A 1983-07-25 1984-07-25 Process of preparing antibodies for inhibiting dental caries induced by streptococcus mutans KR890004123B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP58-135451 1983-07-03
JP58135451A JPS6028937A (en) 1983-07-25 1983-07-25 Noncariogenic antibody and composition

Publications (2)

Publication Number Publication Date
KR850000982A true KR850000982A (en) 1985-03-14
KR890004123B1 KR890004123B1 (en) 1989-10-21

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019840004419A KR890004123B1 (en) 1983-07-25 1984-07-25 Process of preparing antibodies for inhibiting dental caries induced by streptococcus mutans

Country Status (5)

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JP (1) JPS6028937A (en)
KR (1) KR890004123B1 (en)
AU (1) AU3088984A (en)
DE (1) DE3427477A1 (en)
GB (1) GB2143829B (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20020056612A (en) * 2000-12-29 2002-07-10 이남형 The method for production of egg containing anti-Streptococcus mutans IgY, anti-Streptococcus sanguis IgY and anti-Actinomyces israelii IgY individually and egg, yolk, IgY thereof and ice-cream containing complexing specific IgY for anti-Streptococcus mutans, anti-Streptococcus sanguis and anti-Actinomyces israelii
KR100425009B1 (en) * 2000-11-01 2004-04-03 제노백(주) Method of producing an antibody and an antigen for dental caries prevention from Streptococcus mutans
KR100479735B1 (en) * 2002-05-25 2005-03-30 이현철 Non-oral vaccine for preventing dental caries using mannose-coated polymeric micelle-immunoregulator-immunogen complex

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4659561A (en) * 1983-02-18 1987-04-21 The University Of Vermont And State Agricultural College Process for treating the oral cavity
JPH01250067A (en) * 1988-03-30 1989-10-05 Lion Corp Detection of streptococcus mutans
SE9701026D0 (en) * 1997-03-20 1997-03-20 Immun System Ims Ab use of avian antibodies
AU2000270698A1 (en) * 2000-08-24 2002-03-04 Regents Of The Universtiy Of California Immunologic method for the prevention of dental caries
US7875598B2 (en) 2004-03-04 2011-01-25 The Regents Of The University Of California Compositions useful for the treatment of microbial infections
EP2061488B1 (en) 2006-09-06 2014-07-30 The Regents of the University of California Selectively targeted antimicrobial peptides and the use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS521014A (en) * 1975-06-17 1977-01-06 Stolle Res & Dev Pharmaceutically acceptable carrier containing milk immunoglobulin
GB2033223B (en) * 1978-09-01 1983-09-14 Secr Social Service Brit Antigen fromstreptococcus mutans for protection against dental caries
GB2060647B (en) * 1979-10-18 1983-04-13 Russell M W Antigens ex streptococcus mutans
WO1981001101A1 (en) * 1979-10-18 1981-04-30 T Lehner Improvements in or relating to vaccines
US4521513A (en) * 1981-06-19 1985-06-04 The Secretary Of State Of Social Services In Her Britannic Majesty's Government Of The United Kingdon Of Great Brtian And Northern Ireland Protection against dental caries

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100425009B1 (en) * 2000-11-01 2004-04-03 제노백(주) Method of producing an antibody and an antigen for dental caries prevention from Streptococcus mutans
KR20020056612A (en) * 2000-12-29 2002-07-10 이남형 The method for production of egg containing anti-Streptococcus mutans IgY, anti-Streptococcus sanguis IgY and anti-Actinomyces israelii IgY individually and egg, yolk, IgY thereof and ice-cream containing complexing specific IgY for anti-Streptococcus mutans, anti-Streptococcus sanguis and anti-Actinomyces israelii
KR100479735B1 (en) * 2002-05-25 2005-03-30 이현철 Non-oral vaccine for preventing dental caries using mannose-coated polymeric micelle-immunoregulator-immunogen complex

Also Published As

Publication number Publication date
GB8418916D0 (en) 1984-08-30
KR890004123B1 (en) 1989-10-21
DE3427477C2 (en) 1988-11-17
GB2143829A (en) 1985-02-20
AU3088984A (en) 1985-01-31
JPS6028937A (en) 1985-02-14
DE3427477A1 (en) 1985-06-05
JPH0463864B2 (en) 1992-10-13
GB2143829B (en) 1987-10-28

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