KR840000836B1 - Pesticidal compositions - Google Patents

Abstract

Compns. contg. I and o, o-diethyl phosphate derivatives II [A=0, S; B=(III), (IV), (V), (VI), (VII), (VIII) are pesticides. Thus, α-cyano-m-phenoxybenzyl-2, 2-dimethyl-4, 5-benzospiro[2,4 -hepta-4, 6-diene-l-carboxylate and II mixed. at 1:1 were synergistically active against Boophilus microplus (LC50=0.0021%; cotoxicity coeff.=174).

Description

Insecticide composition

The present invention relates to a method for preparing the pesticide composition and its use.

Diethyl 2-chloro-1- (2,4-dichloro) phenyl phosphate is described in detail in US Pat. No. 2,956,073 as a pesticide commonly known as “chlor phenvinforce”.

0,0,0 ', 0', -detraethyl S, S'-methylenedi (phosphorodithioate) is a pesticide known as "ethion" and is described in British Patent No. 872,221 and 0- ( 3-chloro-4-methyl-2-oxy-2H-benzopyran-7-yl) 0,0-diethyl phosphor thioate is described in US Pat. No. 2,748,146 as a pesticide known as “coumaphos”.

0- (4-bromo-2,5-dichlorophenyl) 0,0-diethyl phosphorothioate is a pesticide known as "bromophos ethyl", which is described in British Patent No. 956,343 for pesticides. And 0,0-diethyl-0-2-isopropyl-6-methylpyrimidin-4-yl phosphorothioate is known as "taazinone" and its pesticidal properties are described in British Patent No. 713,278. It is described above.

-시아노-m-페녹시벤질 2,2-디메틸-4,5-ㅏ벤조스피로 [2,4]-헵타-4,6-디엔-1-카르복실레이트는 “시포트린으로 알려진 것으로서 영국 특허명세서 제 1,553,153호에 이것의 살충특성과 함께 그 내용이 상술되어 있다.1,4-dioxane-2,3-diyl S, S-di- (0,0-diethyl phosphorodithioate) is a pesticide known as “dioxathione” and is described in US Pat. Nos. 2,723,328 and 2,815,350. As detailed in

-Cyano-m-phenoxybenzyl 2,2-dimethyl-4,5- ㅏ benzospiro [2,4] -hepta-4,6-diene-1-carboxylate is known as "Sypotrin and is a British patent Specification 1,553,153 describes the content thereof together with its pesticidal properties.

Mixtures of Seafortrin with chlorfenbenfos, ethion, coomaphos, bromophos ethyl, diazinon or dioxation have a large effect on mites such as Boophilus microplus, a single host mite Is being discovered.

Therefore, the pesticide composition according to the present invention

(A) a compound having the formula (I) and

(B) It is composed of a 0,0-diethyl phosphate derivative having the formula (II).

In which A is oxygen and B is a radical having the formula (III),

Or A is sulfur and B is a radical selected from the group consisting of radicals having the following general formulas (IV), (V), (VI), (IX) and (VII).

It should be noted that the compounds of formula (I) may exist in the form of optical isomers or geometric isomers or in the form of mixtures of isomers, ie racemates.

Mixtures of the two compounds having formula (II) may also be contained in the composition, but it is convenient to use a single compound such as chlorophenbinfos, ethion, coomaphos, bromophos ethyl, diazinone or dioxathione.

The weight ratio of the compound of formula (I) to the compound of formula (II) in the composition is preferably in the range of 6: 1-1: 60 and more preferably in the range of 3: 1-1: 40.

Mixtures of compounds of formulas (I) and (II) have a good or insecticidal effect on ticks, such as Bufilus microplus, a single host bovine tick. Therefore, the present invention also relates to a method for removing pests on the locus by applying the pesticidal composition according to the present invention to the locus (gene locus).

In addition, the pesticide composition according to the present invention is a carrier, in particular, at least two carriers, at least one of which is used as a surfactant.

The present invention also relates to a process for preparing the pesticidal composition by containing a compound of formula (I) and a compound of formula (II) in at least one carrier.

The carrier used in the composition according to the present invention may be used in a locus in combination with a surfactant, that is, a substance used in plants, seeds or soil, or easy to transport, store or handle.

Any carrier can be used as long as it is a gas, but any solid or book containing any material that has been compressed into a liquid and can be used in the formulation of the pesticide composition.

Solid carriers suitable for use include natural and artificial clays and silicate salts (e.g. kaolinite, montmorillonite, mica), calcium carbonate, calcium sulfate, artificial silicon oxide hydrate, artificial calcium silicate or aluminum silicate elements (e.g. carbon, sulfur), Natural and synthetic resins (e.g. coumarone resins, polyvinyl chloride, copolymers with styrene polymers), solid polychlorophenols, salts, waxes (biz waxes, paraffin waxes, chlorinated mineral waxes, and solid fertilizers (e.g. superphosphates) Suitable liquid carriers for use include water, alcohols (e.g. isopropanol, glycol), ketones (e.g. acetone, methylethylketone, methylisobutin ketone, cyclohexanone, ether), aromatic or aliphatic hydrocarbons. (Eg benzel, toluene, xylene), petroleum fraction (eg kerosene, light mineral oil), and chlorinated hydrocarbons (eg carbon tetrachloride, perfluoroethylene, trichloroethane). Mixtures with other liquids are also frequently used.

The pesticide composition is combined, transported and diluted in concentrated form for use.

If a small amount of surfactant is added as a carrier, it can be easily diluted.

Surfactants are used as emulsifiers, dispersants, or wetting agents and may be nonionic or ionic.

Suitable surfactants include sodium or calcium salts of polyacrylic acid and ligninsulfonic acid, amide or aliphatic amines having at least 12 carbon atoms in the molecule, or condensation products of fatty acids with ethylene oxide or propylene oxide, glycerol, sorbitan, Fatty acid esters of sucrose or pentaerythritol, condensates of these with ethyl oxide or propylene oxide, fatty alcohols or alkylphenols such as p-octylphenol or p-octycresol and condensation of ethylene or propylene oxide Products, sulfonates or sulfates of these condensation reaction products, alkali or alkaline earth metal salts such as sodium of sulfonic acid or sulfuric acid having at least 10 carbon atoms in the molecule (e.g. sodium lauryl sulfate, sodium secondary sulfate sodium, sodium sulfonated oil) Salts, sodium alkylaryl sulfonic acid (e.g. dodecyl benzenesodium sulfonic acid)], oxidation Ethylene polymers and copolymers of ethylene oxide and propylene oxide.

For example, the composition according to the present invention can be combined into a hydrate powder, granules, solutions, emulsifiable concentrates, emulsions, suspension concentrates and aerosols. The hydrating agents usually contain 25,50 and 75 wt.% Of the active ingredient, in addition to the solid inert antagonist, 3-10 wt.% Of the dispersant, and optionally, stabilizers 0-10 wt.% And other additives such as penetrants or tackifiers. .

It is common to combine powders into powder concentrates with the same composition as a hydrating agent, but do not add a dispersant and in the field add a solid carrier to dilute the composition so that the active ingredient is *** 1 / 2-10wt.%. Granules are usually manufactured to have a particle size of 10-100BS mesh (1.676-0.152 mm) and can be produced by agglomeration method or impregnation method.

Generally, 1 / 2-25 wt.% Of active ingredient and 0-10 wt.% Of additives such as stabilizer, soluble control agent and binder are added to granules. In addition to solvents, emulsifying thickeners usually contain 10-50 w v of cosolvent active ingredient, 2-20% w / v of emulsifier and 0-20% w / v of additives such as stabilizers, penetrants and corrosion inhibitors as required. It is common to combine suspension concentrates into a stable, non-settleable and fluid product, usually 10-75wt.% Active ingredient, 0.5-15wt.% Dispersant, and 0.1-10wt. Suspending agents such as protective colloids and thixotropes. %, 0-10 wt.% Of other additives such as soaps, corrosion inhibitors, stabilizers, penetrants and adhesives, and water or organic liquids in which the active ingredient hardly dissolves, and any organic solid or inorganic salt in the formulation is dissolved to Prevent or act as an antifreeze in water.

Emulsions and liquid dispersions, which are compositions made by moistening the concentrate or the wetting agent according to the invention, fall within the scope of the invention. Emulsions can be made in water-in-oil (W / O) or oil-in-water (OW) or thicker consistency such as mayonnaise. You can also have

In addition, the composition according to the present invention may contain other components, such as pesticides, herbicidal or bactericidal properties, or other compounds or attractants, ie pheromones or food additives used in bait formulations.

According to an embodiment of the present invention will be described in detail.

Example 1

The co-toxicity coefficients of chlorfenbin force and seapotrin were evaluated by the following method.

The single host bovine tick used in this example was a mount alpood species of Bufilus microplus, an OP-resistant strain.

0.1 wt of the active ingredient used in the test was prepared from acetone containing polyethylene glycol (10 wt.%). The solution was diluted to various concentrations. 1 ml of the test solution was placed on a 11 cm filter paper placed in a petri dish. After uniform application and dry enough, the manure paper was folded in half and pleated along the outer edge to form a bundle.

About 80-100 of 2-3 weeks old single host bovine mite larvae (Bupillius microplus) were transferred to this bundle and completely sealed and placed in an incubator with a temperature of 27 ° C. and a relative humidity of 80%. After 24 hours, this bundle was unwrapped and the percentage of larvae that died or died was calculated.

Toxicity Index (T.I.) was calculated using the following equation.

The interaction of the two active ingredients in the mixture is described by Yun-Pei sun and E.R. The analysis was performed following Johnson's method (Journal of Economic Entomology, 1960, Vol. 53, No. 5, pp. 887-892).

Therefore, the co-action of the two pesticides was analyzed by determining the actual toxicity index for each component and the mixture of each compound against the dose-decrease rate curve. The theoretical toxicity of a mixture is equal to the sum of each toxicity index multiplied by the toxicity index calculated from the percentage of each component. Therefore, the co-toxicity and gain co-toxicity coefficients of the mixture are given by

If the modulus of the mixture is close to 100, the action by the two pesticides is similar, and below 100 indicates that the action is different, whereas above 100 indicates synergy.

The results of Example 1 are shown in Table 1 below.

TABLE 1

The co-toxicity coefficients shown in Table 1 clearly show synergy in the mixtures used in the one-sided test.

Example 2-6

The co-toxicity coefficients of the mixture of Seafortrin with Ethion, Coomaphos, Bromophosethyl, Diazinon and Dioxation were evaluated by the following method.

The single host cattle tick used in this example was S-system of Bufilus micronplus.

By the second test, a 5% solution of the active ingredient was prepared in acetone and used for the test. As a secondary test, about half of the acetone was diluted with the active ingredient compound to make LD ₅₆ or so.

A fully congested female tick (Bupillius microphilus) was placed in a petri dish with the stomach facing up, and each test solution was taken with a micrometer syringe, and 2ul was added to the abdomen.

Twelve ticks were treated with each solution in the first and second trials.

Treated mites were placed in a culture incubator with a temperature of 27 ° C. and 80% RH and left for 14 days. The number of eggs produced during this period was reduced, and the eggs were placed for longer periods of time to assess the hatching rate of the eggs (%).

In the first test, the compounds were shown in the following grades.

A≤ 90% less egg mass

B 80 masses reduced

20% reduction in C≤s

Grade A compounds passed LD ₅₀ measurements, using 4 concentrations to obtain dose / response curves and repeated 2-3 times.

Toxicity index was calculated using the following equation.

The synergy with the two active ingredients in the mixture was evaluated in the same manner as in Example 1. The results of Example 2-6 are as shown in Table 2.

TABLE 2

The co-toxicity coefficients in Table 2 clearly show that there is synergy in the mixture used in the test.

Claims (1)

A pesticide composition wherein the compound having the formula (I) and the 0,0-diethyl phosphate derivative having the formula (II) are present in a weight ratio in the range of 3: 1 to 1:40.

Provided that A is oxygen and B is a radical having a compound of formula (III),

Or A is sulfur, B and a radical selected from the group consisting of radicals having the formulas (IV), (V), (VI), (VI), and (VII).