KR830001642A - Aerosol anesthetic composition - Google Patents

Aerosol anesthetic composition Download PDF

Info

Publication number
KR830001642A
KR830001642A KR1019800000950A KR800000950A KR830001642A KR 830001642 A KR830001642 A KR 830001642A KR 1019800000950 A KR1019800000950 A KR 1019800000950A KR 800000950 A KR800000950 A KR 800000950A KR 830001642 A KR830001642 A KR 830001642A
Authority
KR
South Korea
Prior art keywords
benzocaine
solvent
polyethylene glycol
phase mixture
base
Prior art date
Application number
KR1019800000950A
Other languages
Korean (ko)
Inventor
린 송-링
박 무-광
Original Assignee
존 지. 호스만
아메리칸 홈 프로덕트스 코포레이션
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 존 지. 호스만, 아메리칸 홈 프로덕트스 코포레이션 filed Critical 존 지. 호스만
Publication of KR830001642A publication Critical patent/KR830001642A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

내용 없음No content

Description

에어로졸 마취제 조성물Aerosol anesthetic composition

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this content is publicly disclosed, the full text is not included.

Claims (3)

용매내의 벤조케인의 벤조케인의 농도가 0.5% 내지 용매내에서의 최대 용해도까지이고, 용매는 폴리옥시에틸렌쇄에 평균 약 20단위의 에틸렌옥사이드를 갖는 폴리옥시에틸렌 소르비탄 트리올리에이트, 폴리에틸렌글리콜의 평균분자량이 약 400인 폴리에틸렌글리콜 모노라우레이트 및 폴리에틸렌글리콜 디라우레이트중 적어도 하나로부터 선택되며 포사약은 디플루오로 에탄과 적어도 하나의 n-부탄, 이소부탄 및 n-프로판중에서 선택되며, 단 벤조케인이 수세 가능한 염기의 20%를 구성할 경우에는 조성물을 약 -20℃의 온도에서 노출시킨 후 단일상 혼합물로 하는 조건으로서, 용매에 녹인 벤조케인의 수세가능한 염기와 탄화수소 포사약과의 단일상 혼합물로 구성되는, 에어로졸 용기내의 액체 마취제 조성물.The concentration of benzocaine in the solvent is 0.5% to the maximum solubility in the solvent, and the solvent is polyoxyethylene sorbitan trioleate or polyethylene glycol having an average of about 20 units of ethylene oxide in the polyoxyethylene chain. Polyethylene glycol monolaurate and polyethylene glycol dilaurate having an average molecular weight of about 400 are selected from at least one, and the propellant is selected from difluoro ethane and at least one n-butane, isobutane and n-propane, provided that benzo When Kane constitutes 20% of the washable base, the composition is exposed at a temperature of about -20° C., followed by a single-phase mixture, and a single-phase mixture of a water-soluble base of benzocaine dissolved in a solvent and a hydrocarbon forsaking agent. Consisting of, a liquid anesthetic composition in an aerosol container. 벤조케인의 수세가능한 염기는 약 20중량%의 벤조케인, 약 40%의 폴리옥시 에틸렌 소르비탄 트리올리에이트(폴리옥시에틸렌 1개에 평균 약 20단위의 에틸렌옥사이드를 갖는다)및 약 40%의 폴리에틸렌글리콜 모노라우레이트(폴리에틸렌글리콜의 평균분자량은 약 400이다)로 구성되며, 포사약은 디플루오로에탄과 n-부탄이 약 50:50의 중량비로 구성되어 있으며 상기 염기 및 포사약은 각각 조성물의 50%씩으로 구성되는, 용매에 녹인 벤조케인의 수세 가능한 염기와 포사약과의 단일상 혼합물로 구성되는 에어로졸 용기내의 액체 마취제 조성물.The washable base of benzocaine is about 20% by weight of benzocaine, about 40% of polyoxyethylene sorbitan trioleate (one polyoxyethylene has an average of about 20 units of ethylene oxide) and about 40% of polyethylene It consists of glycol monolaurate (average molecular weight of polyethylene glycol is about 400), and the propellant is composed of difluoroethane and n-butane in a weight ratio of about 50:50. A liquid anesthetic composition in an aerosol container consisting of a single phase mixture of a washable base of benzocaine dissolved in a solvent and a porosity, composed of 50% each. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: Disclosure is based on the original application.
KR1019800000950A 1979-03-08 1980-03-07 Aerosol anesthetic composition KR830001642A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1853579A 1979-03-08 1979-03-08
US18535 1979-03-08

Publications (1)

Publication Number Publication Date
KR830001642A true KR830001642A (en) 1983-05-18

Family

ID=21788426

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019800000950A KR830001642A (en) 1979-03-08 1980-03-07 Aerosol anesthetic composition

Country Status (8)

Country Link
KR (1) KR830001642A (en)
CA (1) CA1136547A (en)
CY (1) CY1310A (en)
GB (1) GB2046093B (en)
HK (1) HK85085A (en)
KE (1) KE3558A (en)
MY (1) MY8600371A (en)
SG (1) SG66285G (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8828477D0 (en) * 1988-12-06 1989-01-05 Riker Laboratories Inc Medical aerosol formulations
US5225183A (en) * 1988-12-06 1993-07-06 Riker Laboratories, Inc. Medicinal aerosol formulations
US5766573A (en) * 1988-12-06 1998-06-16 Riker Laboratories, Inc. Medicinal aerosol formulations
US5439670A (en) * 1989-11-28 1995-08-08 Riker Laboratories, Inc. Medicinal aerosol formulations
DE4003270A1 (en) 1990-02-03 1991-08-08 Boehringer Ingelheim Kg NEW SPEED GASES AND THEIR USE IN MEDICINE PREPARATIONS
ES2096653T3 (en) * 1990-06-29 1997-03-16 Fisons Plc COMPOSITIONS OF PRESSURIZED AEROSOL.
GB9103302D0 (en) * 1991-02-16 1991-04-03 Smithkline Beecham Plc Pharmaceutical formulations
IL103238A (en) * 1991-09-25 1995-07-31 Fisons Plc Pressurised aerosol compositions
US5891420A (en) * 1997-04-21 1999-04-06 Aeropharm Technology Limited Environmentally safe triancinolone acetonide aerosol formulations for oral inhalation
US5891419A (en) * 1997-04-21 1999-04-06 Aeropharm Technology Limited Environmentally safe flunisolide aerosol formulations for oral inhalation
US6129905A (en) * 1997-04-21 2000-10-10 Aeropharm Technology, Inc. Aerosol formulations containing a sugar as a dispersant
US6458338B1 (en) 1998-09-22 2002-10-01 Aeropharm Technology Incorporated Amino acid stabilized medicinal aerosol formulations

Also Published As

Publication number Publication date
CY1310A (en) 1986-03-28
HK85085A (en) 1985-11-08
KE3558A (en) 1985-10-04
GB2046093A (en) 1980-11-12
MY8600371A (en) 1986-12-31
SG66285G (en) 1986-06-13
GB2046093B (en) 1983-04-20
CA1136547A (en) 1982-11-30

Similar Documents

Publication Publication Date Title
KR830001642A (en) Aerosol anesthetic composition
KR920700720A (en) Formulation and extinguishing method using hydrofluorocarbon
KR840009031A (en) Process for preparing nimodipine-containing formulation
CO4230158A1 (en) COMPOSITIONS FOR HAIR ARRANGEMENT
ES2102759T3 (en) ALMOST AZEOTROPIC MIXTURES FOR USE AS REFRIGERANTS.
KR840002650A (en) Pharmaceutical Compositions Containing Ubidecarenone
NL7513803A (en) PROCEDURE TO PREVENT PREMATURE VULCANIZATION OF ETHYLENE POLYMER COMPOSITIONS, AND ARTICLES OBTAINED AS SUCH.
DE60336837D1 (en) COOLANT COMPOSITIONS
ATE96836T1 (en) AZEOTROPS OF HYDROGEN CARBONS WITH BUTANES.
US4600575A (en) Aerosol anesthetic compositions
KR830004849A (en) Method of Preparation of Pharmaceutical Formulations
KR920019903A (en) Refrigerant composition
GB925147A (en) Method for the preparation of 2-chloro 3-bromo propene and of propargyl bromide
KR880006305A (en) Foamed Styrene and Styrene Foam
KR880001209A (en) Pesticides
DK132227B (en) Process for the preparation of high molecular weight linear amorphous copolymers of ethylene and propylene or butene-1.
GB982858A (en) Shaped structures of synthetic polymers
SU505635A1 (en) Dioxyperoxide p-fluorobenzaldehyde as the initiator of the processes of sulfochlorination and chlorination of hydrocarbons
GB1235997A (en) Composition for reflowing organic surfaces
JPS5462332A (en) Creamy or milky lotion cosmetics
ES300179A1 (en) Perchlorinated hydrocarbon polymers and their preparation
SU524824A1 (en) Polymer composition
Duffy et al. Correction-" Volumetric and Phase Behavior in the Nitric Acid—Water System"
TH3437B (en) Mixtures as sterilization agents and sterilization methods
SU363733A1 (en) ADHESIVE FOR STICKY TAPES