KR830001221A - 1-benzoyl-3-pyridinyl urea compound - Google Patents

1-benzoyl-3-pyridinyl urea compound Download PDF

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Publication number
KR830001221A
KR830001221A KR1019790002667A KR790002667A KR830001221A KR 830001221 A KR830001221 A KR 830001221A KR 1019790002667 A KR1019790002667 A KR 1019790002667A KR 790002667 A KR790002667 A KR 790002667A KR 830001221 A KR830001221 A KR 830001221A
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South Korea
Prior art keywords
carbon atoms
structural formula
pyridine
halogen
alkyl
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KR1019790002667A
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Korean (ko)
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KR830002348B1 (en
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조오지 수어 로버트
루이스 미셀 존
Original Assignee
아더 알ㆍ웨일
일라이 릴리 앤드 캄파니
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Priority to KR1019790002667A priority Critical patent/KR830002348B1/en
Publication of KR830001221A publication Critical patent/KR830001221A/en
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Publication of KR830002348B1 publication Critical patent/KR830002348B1/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)

Abstract

내용 없음No content

Description

1-벤조일-3-피리디닐 우레아 화합물1-benzoyl-3-pyridinyl urea compound

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음This content is subject to disclosure, so the full text is not included.

Claims (1)

다음 구조식(II)의 벤조일 이소시아네이트 또는 벤조일 이소티오시아네이트를 다음 구조식(III)의 아미노피리딘 또는 이의 N-옥사이드와 반응시킴을 특징으로 하여 다음 구조식(I) 화합물, 이의 산부가염 및 이의 N-옥사이드를 제조하는 방법.The following structural formula (I) compound, its acid addition salt and its N-oxide, characterized by reacting benzoyl isocyanate or benzoyl isothiocyanate of the following structural formula (II) with an aminopyridine of the following structural formula (III) or an N-oxide thereof. How to manufacture. 상기 구조식에서,In the above structural formula, R1은 할로겐 또는 탄소수 1 내지 3의 알킬이고,R 1 is halogen or alkyl having 1 to 3 carbon atoms, R2는 -O-, -S-,이고,R 2 is -O-, -S-, ego, R3는 탄소수 1 내지 5의 알킬, α, β가 불포화되지 않은 탄소수 3 내지 5의 알케닐, 탄소수 1 내지 5의 할로알킬, 탄소수 4 내지 8의 사이클로알킬, 탄소수 2 내지 5의 알콕시알킬이거나 또는 할로겐, 탄소수 1 내지 3의 할로알킬 또는 할로알콕시, 탄소수 1 내지 3의 알킬 또는 메톡시로 임의 치환된 페닐이고,R 3 is alkyl having 1 to 5 carbon atoms, alkenyl having 3 to 5 carbon atoms in which α, β are unsaturated, haloalkyl having 1 to 5 carbon atoms, cycloalkyl having 4 to 8 carbon atoms, alkoxyalkyl having 2 to 5 carbon atoms or Phenyl optionally substituted with halogen, haloalkyl or haloalkoxy having 1 to 3 carbon atoms, alkyl or methoxy having 1 to 3 carbon atoms, R4및 R5는 같거나 다르게 수소, 할로겐, 메틸 또는 메톡시이고,R 4 and R 5 are the same or differently hydrogen, halogen, methyl or methoxy, m 및 n은 같거나 다르게 각각 0 또는 1이고,m and n are the same or different, each 0 or 1, x는 산소 또는 황이고,x is oxygen or sulfur, 피리딘 결합되어 있는 질소원자는 피리딘환의 2- 또는 3- 위치에 있으며,The nitrogen atom to which the pyridine is bonded is at the 2- or 3-position of the pyridine ring, 단 (A) R4및 R5는 모두 수소가 될 수 없고, R4및 R5중 하나가 수소일 경우 다른 하나는 클로로이고, R3는 트리플루오로메틸그룹으로 치환된 페닐이며,Provided that (A) R 4 and R 5 cannot both be hydrogen, and when one of R 4 and R 5 is hydrogen, the other is chloro, and R 3 is phenyl substituted with a trifluoromethyl group, (B) 피리딘 결합되어 있는 질소원자가 2-위치에 있을 때 R3-(CH2)n-R3그룹은 5-위치에 있으며,(B) When the nitrogen atom to which the pyridine is bonded is in the 2-position, the R 3 -(CH 2 )nR 3 group is in the 5-position, (C) 피리딘 결합되어 있는 질소원자가 3-위치에 있을 때 R2-(CH2)n-R3그룹은 6-위치에 있다.(C) When the nitrogen atom to which the pyridine is bonded is in the 3-position, the R 2 -(CH 2 )nR 3 group is in the 6-position. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: It is disclosed according to the contents of the initial application.
KR1019790002667A 1979-08-06 1979-08-06 Method for preparing 1-benzoyl-3-pyridinyl urea compound KR830002348B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019790002667A KR830002348B1 (en) 1979-08-06 1979-08-06 Method for preparing 1-benzoyl-3-pyridinyl urea compound

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019790002667A KR830002348B1 (en) 1979-08-06 1979-08-06 Method for preparing 1-benzoyl-3-pyridinyl urea compound

Publications (2)

Publication Number Publication Date
KR830001221A true KR830001221A (en) 1983-04-29
KR830002348B1 KR830002348B1 (en) 1983-10-24

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KR1019790002667A KR830002348B1 (en) 1979-08-06 1979-08-06 Method for preparing 1-benzoyl-3-pyridinyl urea compound

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KR830002348B1 (en) 1983-10-24

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