KR830000834A - Process for preparing 2,6 - methano - 3 - benzazocines - Google Patents

Process for preparing 2,6 - methano - 3 - benzazocines

Info

Publication number
KR830000834A
KR830000834A KR7801257A KR780001257A KR830000834A KR 830000834 A KR830000834 A KR 830000834A KR 7801257 A KR7801257 A KR 7801257A KR 780001257 A KR780001257 A KR 780001257A KR 830000834 A KR830000834 A KR 830000834A
Authority
KR
South Korea
Prior art keywords
benzazocines
methano
preparing
pentyl
methanobenzazocines
Prior art date
Application number
KR7801257A
Other languages
Korean (ko)
Other versions
KR830000834B1 (en
Inventor
T Miller
W Michne
P Dupont
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Priority to KR1019780001257A priority Critical patent/KR830000834B1/en
Application granted granted Critical
Publication of KR830000834B1 publication Critical patent/KR830000834B1/en
Publication of KR830000834A publication Critical patent/KR830000834A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

Methanobenzazocines I(R=Me, Pentyl, CH2CH2CHMe2, CH2CH2Ph, C3-5 cycloalkylethyl; R1=H) were prepd. Thus I(R=pentyl, R1=H) was obtained by treating II with 98% HCO2H and dimethy-eating I(R=pentyl, R1=Me) with 48% H Br.
KR1019780001257A 1978-04-26 1978-04-26 2.6-Metano-3-benzazosin preparation method KR830000834B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019780001257A KR830000834B1 (en) 1978-04-26 1978-04-26 2.6-Metano-3-benzazosin preparation method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019780001257A KR830000834B1 (en) 1978-04-26 1978-04-26 2.6-Metano-3-benzazosin preparation method

Publications (2)

Publication Number Publication Date
KR830000834B1 KR830000834B1 (en) 1983-04-20
KR830000834A true KR830000834A (en) 1983-04-20

Family

ID=19207541

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019780001257A KR830000834B1 (en) 1978-04-26 1978-04-26 2.6-Metano-3-benzazosin preparation method

Country Status (1)

Country Link
KR (1) KR830000834B1 (en)

Also Published As

Publication number Publication date
KR830000834B1 (en) 1983-04-20

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