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A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K9/00—Medicinal preparations characterised by special physical form
A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
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Abstract
내용 없음No content
Description
서방출형 제제의 제조방법Manufacturing method of sustained-release formulation
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음This content is subject to disclosure, so the full text is not included.
Claims (2)
a) 아릴알카놀아민 또는 아릴옥시알카놀아민과 같은 약학적 활성물질과 b) 고급지방알코올의 모노설푸린산 에스텔과 같은 약학적으로 무독한 음이온 계면활성제를 혼합하여 심정을 제조하고 약물심정을 위액에 대해서는 안정하지만 pH 5이상에서는 붕괴하는 필름으로 코팅하고 임의로 위액에 용해할 수 있는 약물층을 필름코팅된 약물 심정위에 입힘을 특징으로 하는 위장관에서 활성성분의 방출속도를 조절할 수 있는 제제의 제조방법.a) a pharmacologically active substance such as arylalkanolamine or aryloxyalkanolamine and b) a pharmaceutically non-toxic anionic surfactant such as monosulfuric acid ester of a higher fatty alcohol is mixed to prepare a cardiac tablet, and Preparation of a formulation capable of controlling the release rate of the active ingredient in the gastrointestinal tract, characterized by coating with a film that is stable against gastric juice but disintegrating at pH 5 and applying a film-coated drug layer that can be dissolved in the gastric juice on a film Way.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: It is disclosed according to the contents of the initial application.
KR7701701A1977-07-231977-07-23Process for preparing pharmaceutical formulation controlled release
KR830001644B1
(en)