KR20240148426A - 2-히드록시프로필-베타-사이클로덱스트린으로 고-트리글리세리드혈증을 치료 - Google Patents

2-히드록시프로필-베타-사이클로덱스트린으로 고-트리글리세리드혈증을 치료 Download PDF

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Publication number
KR20240148426A
KR20240148426A KR1020247030936A KR20247030936A KR20240148426A KR 20240148426 A KR20240148426 A KR 20240148426A KR 1020247030936 A KR1020247030936 A KR 1020247030936A KR 20247030936 A KR20247030936 A KR 20247030936A KR 20240148426 A KR20240148426 A KR 20240148426A
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KR
South Korea
Prior art keywords
amount
subject
administration
cyclodextrin
therapeutically effective
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
KR1020247030936A
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English (en)
Korean (ko)
Inventor
제이슨 캠
Original Assignee
베렌 테라퓨틱스 피.비.씨.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 베렌 테라퓨틱스 피.비.씨. filed Critical 베렌 테라퓨틱스 피.비.씨.
Publication of KR20240148426A publication Critical patent/KR20240148426A/ko
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/724Cyclodextrins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
KR1020247030936A 2022-02-18 2023-02-17 2-히드록시프로필-베타-사이클로덱스트린으로 고-트리글리세리드혈증을 치료 Pending KR20240148426A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263311536P 2022-02-18 2022-02-18
US63/311,536 2022-02-18
PCT/IB2023/051467 WO2023156970A1 (en) 2022-02-18 2023-02-17 Treatment of hypertriglyceridemia with 2-hydroxypropyl-beta-cyclodextrin

Publications (1)

Publication Number Publication Date
KR20240148426A true KR20240148426A (ko) 2024-10-11

Family

ID=85476260

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020247030936A Pending KR20240148426A (ko) 2022-02-18 2023-02-17 2-히드록시프로필-베타-사이클로덱스트린으로 고-트리글리세리드혈증을 치료

Country Status (11)

Country Link
US (1) US20240398849A1 (https=)
EP (1) EP4479064A1 (https=)
JP (1) JP2025508660A (https=)
KR (1) KR20240148426A (https=)
CN (1) CN118715017A (https=)
AU (1) AU2023222567A1 (https=)
CA (1) CA3244447A1 (https=)
IL (1) IL315046A (https=)
MX (1) MX2024010110A (https=)
TW (1) TW202342072A (https=)
WO (1) WO2023156970A1 (https=)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0307518A (pt) * 2002-02-01 2004-12-28 Shimoda Biotech Pty Ltd Composição farmacêutica
CN1745746A (zh) * 2004-09-09 2006-03-15 天津药物研究院 冰片的羟丙基-β-环糊精包合物及其制剂和制备方法
CN1961892A (zh) * 2005-11-08 2007-05-16 天津药物研究院 降香羟丙基-β-环糊精包合物及其制剂和制备方法
GB0710439D0 (en) * 2007-05-31 2007-07-11 Uni I Oslo Oral dosage form
JP5847721B2 (ja) * 2009-10-08 2016-01-27 ソン、ホ、バイオメッド、カンパニー、リミテッドSong Ho Biomed Co., Ltd 高水溶性2−ヒドロキシプロピル−ベータシクロデキストリンを有効成分として含有する、肥満疾患の予防および治療用組成物
FR3014694B1 (fr) * 2013-12-13 2016-11-11 Roquette Freres Compositions a base de methyl-cyclodextrines pour le traitement et/ou la prevention de maladies par augmentation du taux de cholesterol-hdl

Also Published As

Publication number Publication date
IL315046A (en) 2024-10-01
WO2023156970A1 (en) 2023-08-24
JP2025508660A (ja) 2025-04-10
AU2023222567A1 (en) 2024-09-19
US20240398849A1 (en) 2024-12-05
CA3244447A1 (en) 2023-08-24
MX2024010110A (es) 2024-08-30
EP4479064A1 (en) 2024-12-25
TW202342072A (zh) 2023-11-01
CN118715017A (zh) 2024-09-27

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