KR20240118877A - Rna 구조체 - Google Patents

Rna 구조체 Download PDF

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Publication number
KR20240118877A
KR20240118877A KR1020247023956A KR20247023956A KR20240118877A KR 20240118877 A KR20240118877 A KR 20240118877A KR 1020247023956 A KR1020247023956 A KR 1020247023956A KR 20247023956 A KR20247023956 A KR 20247023956A KR 20240118877 A KR20240118877 A KR 20240118877A
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South Korea
Prior art keywords
seq
rna
nucleotide sequence
isp
variant
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KR1020247023956A
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Korean (ko)
Inventor
폴 맥케이
로빈 샤톡
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임피리얼 컬리지 이노베이션스 리미티드
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Publication of KR20240118877A publication Critical patent/KR20240118877A/ko
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    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • C07K14/523—Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
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  • Bioinformatics & Cheminformatics (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Cell Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
KR1020247023956A 2021-12-17 2022-12-16 Rna 구조체 Pending KR20240118877A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB202118464 2021-12-17
GB2118464.3 2021-12-17
PCT/GB2022/053275 WO2023111592A1 (en) 2021-12-17 2022-12-16 Rna construct

Publications (1)

Publication Number Publication Date
KR20240118877A true KR20240118877A (ko) 2024-08-05

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ID=84627358

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020247023956A Pending KR20240118877A (ko) 2021-12-17 2022-12-16 Rna 구조체

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US (1) US20250051798A1 (https=)
EP (1) EP4448774A1 (https=)
JP (1) JP2024546964A (https=)
KR (1) KR20240118877A (https=)
CN (1) CN118715325A (https=)
AU (1) AU2022416947A1 (https=)
WO (1) WO2023111592A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202313445D0 (en) 2023-09-04 2023-10-18 Imperial College Innovations Ltd Rna molecule
WO2025189168A1 (en) * 2024-03-08 2025-09-12 SunVax mRNA Therapeutics Inc. Methods for cascade amplifications of therapeutic payloads (catp) & compositions for cancer immunotherapies and gene therapy

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201118636D0 (en) 2011-10-28 2011-12-07 Oxford Biomedica Ltd Nucleotide sequence
GB201908729D0 (en) * 2019-06-18 2019-07-31 Imp College Innovations Ltd RNA construct

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Publication number Publication date
WO2023111592A1 (en) 2023-06-22
JP2024546964A (ja) 2024-12-26
EP4448774A1 (en) 2024-10-23
US20250051798A1 (en) 2025-02-13
AU2022416947A1 (en) 2024-07-04
CN118715325A (zh) 2024-09-27

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