KR20240070858A - 비침습적 알츠하이머 위험 검사장치 및 검사방법 - Google Patents
비침습적 알츠하이머 위험 검사장치 및 검사방법 Download PDFInfo
- Publication number
- KR20240070858A KR20240070858A KR1020220152282A KR20220152282A KR20240070858A KR 20240070858 A KR20240070858 A KR 20240070858A KR 1020220152282 A KR1020220152282 A KR 1020220152282A KR 20220152282 A KR20220152282 A KR 20220152282A KR 20240070858 A KR20240070858 A KR 20240070858A
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- Prior art keywords
- index
- amyloid
- retina
- risk
- alzheimer
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Links
- 238000012360 testing method Methods 0.000 title claims abstract description 55
- 238000000034 method Methods 0.000 title description 3
- 210000001525 retina Anatomy 0.000 claims abstract description 90
- 238000004364 calculation method Methods 0.000 claims abstract description 82
- 230000002207 retinal effect Effects 0.000 claims abstract description 52
- 102000009091 Amyloidogenic Proteins Human genes 0.000 claims abstract description 32
- 108010048112 Amyloidogenic Proteins Proteins 0.000 claims abstract description 32
- 238000012113 quantitative test Methods 0.000 claims abstract description 11
- 102000004169 proteins and genes Human genes 0.000 claims abstract description 3
- 108090000623 proteins and genes Proteins 0.000 claims abstract description 3
- 206010012289 Dementia Diseases 0.000 claims description 40
- 238000010998 test method Methods 0.000 claims description 10
- 206010025421 Macule Diseases 0.000 claims description 6
- 230000003287 optical effect Effects 0.000 claims description 6
- 238000012216 screening Methods 0.000 claims 1
- 210000002569 neuron Anatomy 0.000 description 7
- 208000024827 Alzheimer disease Diseases 0.000 description 5
- 210000004556 brain Anatomy 0.000 description 5
- 230000007082 Aβ accumulation Effects 0.000 description 4
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- 238000003384 imaging method Methods 0.000 description 4
- 238000001574 biopsy Methods 0.000 description 3
- 230000003920 cognitive function Effects 0.000 description 3
- 230000003930 cognitive ability Effects 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 238000013399 early diagnosis Methods 0.000 description 2
- 210000001508 eye Anatomy 0.000 description 2
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- 238000004393 prognosis Methods 0.000 description 2
- CVOFKRWYWCSDMA-UHFFFAOYSA-N 2-chloro-n-(2,6-diethylphenyl)-n-(methoxymethyl)acetamide;2,6-dinitro-n,n-dipropyl-4-(trifluoromethyl)aniline Chemical compound CCC1=CC=CC(CC)=C1N(COC)C(=O)CCl.CCCN(CCC)C1=C([N+]([O-])=O)C=C(C(F)(F)F)C=C1[N+]([O-])=O CVOFKRWYWCSDMA-UHFFFAOYSA-N 0.000 description 1
- 201000004569 Blindness Diseases 0.000 description 1
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- 208000025966 Neurological disease Diseases 0.000 description 1
- 206010039203 Road traffic accident Diseases 0.000 description 1
- 206010039966 Senile dementia Diseases 0.000 description 1
- 201000004810 Vascular dementia Diseases 0.000 description 1
- 230000003941 amyloidogenesis Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 208000035850 clinical syndrome Diseases 0.000 description 1
- 230000001149 cognitive effect Effects 0.000 description 1
- 230000003412 degenerative effect Effects 0.000 description 1
- 238000012217 deletion Methods 0.000 description 1
- 230000037430 deletion Effects 0.000 description 1
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- 229940079593 drug Drugs 0.000 description 1
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- 238000011158 quantitative evaluation Methods 0.000 description 1
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Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/40—Detecting, measuring or recording for evaluating the nervous system
- A61B5/4076—Diagnosing or monitoring particular conditions of the nervous system
- A61B5/4088—Diagnosing of monitoring cognitive diseases, e.g. Alzheimer, prion diseases or dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/0008—Apparatus for testing the eyes; Instruments for examining the eyes provided with illuminating means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/0016—Operational features thereof
- A61B3/0025—Operational features thereof characterised by electronic signal processing, e.g. eye models
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/12—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/14—Arrangements specially adapted for eye photography
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/14—Arrangements specially adapted for eye photography
- A61B3/145—Arrangements specially adapted for eye photography by video means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/50—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Medical Informatics (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Surgery (AREA)
- Molecular Biology (AREA)
- Ophthalmology & Optometry (AREA)
- Pathology (AREA)
- Databases & Information Systems (AREA)
- Data Mining & Analysis (AREA)
- Epidemiology (AREA)
- Primary Health Care (AREA)
- Neurology (AREA)
- Developmental Disabilities (AREA)
- Child & Adolescent Psychology (AREA)
- Multimedia (AREA)
- Hospice & Palliative Care (AREA)
- Signal Processing (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Neurosurgery (AREA)
- Physiology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020220152282A KR20240070858A (ko) | 2022-11-15 | 2022-11-15 | 비침습적 알츠하이머 위험 검사장치 및 검사방법 |
| PCT/KR2023/017989 WO2024106850A1 (fr) | 2022-11-15 | 2023-11-09 | Dispositif non invasif de test du risque d'alzheimer et méthode de test |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020220152282A KR20240070858A (ko) | 2022-11-15 | 2022-11-15 | 비침습적 알츠하이머 위험 검사장치 및 검사방법 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20240070858A true KR20240070858A (ko) | 2024-05-22 |
Family
ID=91085128
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020220152282A KR20240070858A (ko) | 2022-11-15 | 2022-11-15 | 비침습적 알츠하이머 위험 검사장치 및 검사방법 |
Country Status (2)
| Country | Link |
|---|---|
| KR (1) | KR20240070858A (fr) |
| WO (1) | WO2024106850A1 (fr) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2420179B1 (fr) * | 2010-08-16 | 2020-10-07 | Cognoptix, Inc. | Système et procédé de détection de protéines d'amyloïdes |
| AU2018372578A1 (en) * | 2017-11-27 | 2020-06-11 | Retispec Inc. | Hyperspectral image-guided raman ocular imager for Alzheimer's Disease pathologies |
| EP3737922A4 (fr) * | 2018-01-11 | 2021-10-20 | Centre for Eye Research Australia Limited | Procédé et système de quantification d'un biomarqueur d'un tissu |
| KR102378306B1 (ko) * | 2020-05-06 | 2022-03-25 | (주)자이온프로세스 | 알츠하이머 진단 장치 및 방법 |
| KR102418399B1 (ko) * | 2020-12-04 | 2022-07-07 | 주식회사 에이아이플랫폼 | 인공지능 기반 치매 조기 진단 플랫폼 |
-
2022
- 2022-11-15 KR KR1020220152282A patent/KR20240070858A/ko unknown
-
2023
- 2023-11-09 WO PCT/KR2023/017989 patent/WO2024106850A1/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2024106850A1 (fr) | 2024-05-23 |
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