KR20240049212A - 당뇨병성 망막병증 및 관련 병태의 치료 방법 및 조성물 - Google Patents

당뇨병성 망막병증 및 관련 병태의 치료 방법 및 조성물 Download PDF

Info

Publication number
KR20240049212A
KR20240049212A KR1020237041163A KR20237041163A KR20240049212A KR 20240049212 A KR20240049212 A KR 20240049212A KR 1020237041163 A KR1020237041163 A KR 1020237041163A KR 20237041163 A KR20237041163 A KR 20237041163A KR 20240049212 A KR20240049212 A KR 20240049212A
Authority
KR
South Korea
Prior art keywords
therapeutic agent
patient
orally
paragraphs
administered
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
KR1020237041163A
Other languages
English (en)
Korean (ko)
Inventor
미나 수치
콘스탄티노스 카리자니스
마크 아르. 켈리
리처드 애덤 매스맨
미쉘 조지 브라이젤
로닐 아제이쿠마르 파텔
Original Assignee
오큐파이어 파마, 인크.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 오큐파이어 파마, 인크. filed Critical 오큐파이어 파마, 인크.
Publication of KR20240049212A publication Critical patent/KR20240049212A/ko
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/201Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020237041163A 2021-04-30 2022-04-29 당뇨병성 망막병증 및 관련 병태의 치료 방법 및 조성물 Pending KR20240049212A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163182037P 2021-04-30 2021-04-30
US63/182,037 2021-04-30
PCT/US2022/027062 WO2022232597A1 (en) 2021-04-30 2022-04-29 Methods and compositions for treatment of diabetic retinopathy and related conditions

Publications (1)

Publication Number Publication Date
KR20240049212A true KR20240049212A (ko) 2024-04-16

Family

ID=83848745

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020237041163A Pending KR20240049212A (ko) 2021-04-30 2022-04-29 당뇨병성 망막병증 및 관련 병태의 치료 방법 및 조성물

Country Status (11)

Country Link
US (1) US20240216315A1 (https=)
EP (1) EP4329741A4 (https=)
JP (1) JP2024516003A (https=)
KR (1) KR20240049212A (https=)
CN (1) CN117500492A (https=)
AU (1) AU2022264037A1 (https=)
BR (1) BR112023022561A2 (https=)
CA (1) CA3217136A1 (https=)
IL (1) IL308083A (https=)
MX (1) MX2023012793A (https=)
WO (1) WO2022232597A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4587003A2 (en) 2022-09-14 2025-07-23 Opus Genetics, Inc. Salts and esters of apx3330 and therapeutic uses thereof
WO2024158972A1 (en) * 2023-01-25 2024-08-02 Ocuphire Pharma, Inc. Methods and compositions for preventing the progression of diabetic retinopathy and related conditions

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2008304619C1 (en) * 2007-09-26 2020-06-04 Indiana University Research And Technology Corporation Benzoquinone derivative E3330 in combination with chemotherapeutic agents for the treatment of cancer and angiogenesis
AU2019218797B2 (en) * 2018-02-08 2023-09-21 Indiana University Research And Technology Corporation Targeting ocular diseases with novel APE1/Ref-1 inhibitors

Also Published As

Publication number Publication date
BR112023022561A2 (pt) 2024-01-02
MX2023012793A (es) 2024-01-11
US20240216315A1 (en) 2024-07-04
CA3217136A1 (en) 2022-11-03
JP2024516003A (ja) 2024-04-11
CN117500492A (zh) 2024-02-02
IL308083A (en) 2023-12-01
AU2022264037A1 (en) 2023-11-16
EP4329741A4 (en) 2025-01-08
EP4329741A1 (en) 2024-03-06
WO2022232597A1 (en) 2022-11-03

Similar Documents

Publication Publication Date Title
JP5341933B2 (ja) 腹圧性尿失禁の予防・治療剤及びそのスクリーニング方法
KR100723189B1 (ko) 눈에 국소적으로 사용하기 위한 브리모니딘과 티몰롤의조합물
AU2007314734B2 (en) Use of testosterone and a 5-HT1A agonist in the treatment of sexual dysfunction
CN114845718B (zh) 用于治疗与过度血管形成相关的眼部疾病的化合物
US20230089914A1 (en) Compositions comprising axitinib and methods of treating ocular disorders
MX2012007941A (es) Farmaceutico para impedir o tratar alteraciones acompañadas por angiogenesis ocular y/o permeabilidad vascular ocular elevada.
IL148159A (en) Methods in Depoxytin Ann is a common pharmacological word in the manufacture of a drug for the treatment or control of sexual dysfunction
US12102640B2 (en) Use of dopamine and serotonin receptor antagonists for treatment in a subject with retinal degeneration
KR20240162094A (ko) 미르다메티닙 치료
KR20240049212A (ko) 당뇨병성 망막병증 및 관련 병태의 치료 방법 및 조성물
US20050043220A1 (en) Methods and compositions for treating macular degeneration
US20240148709A1 (en) Methods of treating eye pain and eye disorders
US20230201225A1 (en) Methods of treating multiple sclerosis
US20260108483A1 (en) Methods and compositions for preventing the progression of diabetic retinopathy and related conditions
Kuriyan et al. Improvement of thyroid eye disease following treatment with the cyclooxygenase-2 selective inhibitor celecoxib
US20030225101A1 (en) Method of treating retinal occlusion with sildenafil
RU2854294C2 (ru) Ингибитор cdk4 для лечения рака
US20250195528A1 (en) Dose regimen of vicasinabin
JP2024518787A (ja) 全身型重症筋無力症の処置のための補体因子d阻害剤の使用
US20080234351A1 (en) Combination Methods for Preserving Visual Acuity
KR20240102577A (ko) 당뇨망막병증의 예방 및 치료를 위한 다파글리플로진을 함유하는 약제학적 조성물
HK1190945A (en) Use of testosterone and a 5-ht1a agonist in the treatment of sexual dysfunction
HK1135038B (en) Use of testosterone and a 5-ht1a agonist in the treatment of sexual dysfunction

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20231129

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20250428

Comment text: Request for Examination of Application