KR20240000562A - 분석용 hplc - Google Patents

분석용 hplc Download PDF

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Publication number
KR20240000562A
KR20240000562A KR1020237040178A KR20237040178A KR20240000562A KR 20240000562 A KR20240000562 A KR 20240000562A KR 1020237040178 A KR1020237040178 A KR 1020237040178A KR 20237040178 A KR20237040178 A KR 20237040178A KR 20240000562 A KR20240000562 A KR 20240000562A
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KR
South Korea
Prior art keywords
mobile phase
organic solvent
acid
radiopharmaceutical
fluoride
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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KR1020237040178A
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English (en)
Korean (ko)
Inventor
앨런 클라크
헨드릭 페트루스 엥겔브레츠
줄리안 그릭
임티아즈 아메드 칸
크리스틴 위켄
그레이엄 맥로비
Original Assignee
지이 헬쓰케어 리미티드
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Publication of KR20240000562A publication Critical patent/KR20240000562A/ko
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/34—Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/0093—Radioactive materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N2030/022—Column chromatography characterised by the kind of separation mechanism
    • G01N2030/027—Liquid chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/884—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample organic compounds
    • G01N2030/8845—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample organic compounds involving halogenated organic compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/8859—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample inorganic compounds
    • G01N2033/0093—

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
KR1020237040178A 2021-04-26 2022-04-26 분석용 hplc Pending KR20240000562A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB2105950.6 2021-04-26
GBGB2105950.6A GB202105950D0 (en) 2021-04-26 2021-04-26 Analytical HPLC
PCT/EP2022/061004 WO2022229155A1 (en) 2021-04-26 2022-04-26 Analytical hplc

Publications (1)

Publication Number Publication Date
KR20240000562A true KR20240000562A (ko) 2024-01-02

Family

ID=76193425

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020237040178A Pending KR20240000562A (ko) 2021-04-26 2022-04-26 분석용 hplc

Country Status (12)

Country Link
US (1) US20240302338A1 (https=)
EP (1) EP4330662B1 (https=)
JP (1) JP2024518319A (https=)
KR (1) KR20240000562A (https=)
CN (1) CN117222890A (https=)
AU (1) AU2022264815A1 (https=)
CA (1) CA3217818A1 (https=)
ES (1) ES3050308T3 (https=)
GB (1) GB202105950D0 (https=)
IL (1) IL307946A (https=)
PL (1) PL4330662T3 (https=)
WO (1) WO2022229155A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201915206D0 (en) 2019-10-21 2019-12-04 Ge Healthcare Ltd Use of cyclodextrins as a radiostabilizer
CN119688861A (zh) * 2024-11-29 2025-03-25 中国辐射防护研究院 一种生物样本中18f-psma-1007放化纯的液相色谱分析方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5300280A (en) * 1992-02-14 1994-04-05 Mallinckrodt Medical, Inc. Stabilized radiopharmaceutical kits
ES2398393T3 (es) * 2002-03-01 2013-03-15 Dyax Corp. Péptidos de unión a KDR y a VEGF/KDR y su uso en diagnóstico y terapia
JP4942953B2 (ja) * 2005-06-30 2012-05-30 サントリーホールディングス株式会社 プロシアニジンの分析方法
US8214159B2 (en) * 2008-12-04 2012-07-03 Siemens Medical Solutions Usa, Inc. Apparatus and method for automated quality control
GB201013808D0 (en) * 2010-08-18 2010-09-29 Ge Healthcare Ltd Peptide radiotracer compositions
EP2450332A1 (en) * 2010-10-22 2012-05-09 Bayer Pharma Aktiengesellschaft Compounds for use in Imaging, diagnosing and/or treatment of diseases of the central nervous system (F-D2-Deprenyl)
GB201202420D0 (en) * 2012-02-13 2012-03-28 Ge Healthcare Ltd Radiotracer compositions
CN104718299B (zh) * 2012-08-13 2024-02-06 通用医院公司 用于线粒体复合物i的定量定位的系统和方法
GB201303830D0 (en) * 2013-03-04 2013-04-17 Univ Glasgow Methods,unit and device relating to the manufacture,processing,synthesising or screening of radiopharmaceutical compositions
GB201418893D0 (en) * 2014-10-23 2014-12-10 Univ Hull Monolithic body
GB201805253D0 (en) * 2018-03-29 2018-05-16 Ge Healthcare Ltd Ip Solid phase extraction
CN111333638A (zh) * 2020-03-17 2020-06-26 四川大学华西医院 18f标记的异喹啉并哒嗪酮类化合物及其合成方法和应用

Also Published As

Publication number Publication date
EP4330662A1 (en) 2024-03-06
EP4330662B1 (en) 2025-09-03
PL4330662T3 (pl) 2025-11-12
JP2024518319A (ja) 2024-05-01
IL307946A (en) 2023-12-01
ES3050308T3 (en) 2025-12-19
CN117222890A (zh) 2023-12-12
US20240302338A1 (en) 2024-09-12
CA3217818A1 (en) 2022-11-03
WO2022229155A1 (en) 2022-11-03
EP4330662C0 (en) 2025-09-03
AU2022264815A1 (en) 2023-10-26
GB202105950D0 (en) 2021-06-09

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Patent event date: 20231122

Patent event code: PA01051R01D

Comment text: International Patent Application

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Patent event code: PA02012R01D

Patent event date: 20250328

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