KR20230154725A - Mask patch for blocking Ultraviolet light comprising microneedle - Google Patents

Abstract

The present invention relates to a mask patch for blocking ultraviolet rays. The UV-blocking mask patch of the present invention has excellent UV-blocking effect and is equipped with a microneedle patch, so it has superior adhesive strength compared to a general mask patch and can deliver useful ingredients to the skin.

Description

Mask patch for blocking Ultraviolet light comprising microneedle}

The present invention relates to a mask patch for UV protection equipped with microneedles.

Recently, as interest in outdoor sports and leisure activities has increased, there is a problem of increased exposure to ultraviolet rays on the skin due to outdoor activities. Ultraviolet rays are known to be a major cause of skin aging, erythema, freckles, and skin cancer. Accordingly, a variety of products that can be applied to the skin, such as sunscreen and sun sticks, have been released to block ultraviolet rays, and products that cover the entire face, such as masks to block ultraviolet rays, have also been released. However, skin-applied sunscreen products do not have a great sunscreen effect and are inconvenient as they come off when you sweat and require additional application in between, and sunblock masks cover the entire face, which is not good for appearance and causes intense exposure. There were disadvantages to exercising, such as difficulty breathing. Accordingly, there is a need to develop products that do not come off even when sweating, are easy to use even during intense exercise, and have excellent UV protection.

In order to solve the above-mentioned problem, the present inventors have made extensive research efforts to develop a UV-blocking product that is not removed even when sweating, is easy to use even during intense exercise, and has an excellent UV-blocking function. As a result, a mask patch with UV blocking function was manufactured, and it was confirmed that if the mask patch is equipped with a microneedle patch, it can block UV rays, but also has better skin adhesion and can effectively deliver skin useful ingredients. The invention was completed.

Therefore, the purpose of the present invention is to provide a mask patch for blocking ultraviolet rays equipped with microneedles.

According to one aspect of the present invention, the present invention provides a mask patch for UV protection comprising:

Sheets with UV protection; And one or more microneedle patches attached to the side of the sheet that is in contact with the face.

In one embodiment of the present invention, the UV-blocking mask patch is attached to the cheekbone area under the eyes, the cheek area, or over the nose to protect the skin. The UV-blocking mask patch is not attached to the mouth and nostrils to avoid discomfort in breathing.

In one embodiment of the present invention, the UV-blocking mask patch (1) of the present invention includes (a) a sheet (10) with a UV-blocking function as described above; and (b) one or more microneedle patches (20) are attached to one of both sides of the sheet, which is in contact with the face.

In one embodiment of the present invention, the sheet with the UV blocking function may be made of an elastic fabric.

In one embodiment of the present invention, the sheet with the UV blocking function may be made of a fabric containing hydrocolloid. Hydrophilic polymers constituting the hydrocolloid include natural hydrophilic polymers such as pectin, gelatin, and cellulose, specifically carboxymethylcellulose (CMC), collagen, dextran, elastin, chitin, chitosan, and sodium alginate; Or synthetic hydrophilic polymers such as polyacrylic acid (PAA), polyvinyl alcohol, polyethylene glycol, polyvinyl pyrrolidone, polyurethane, polyhydroxyethyl methacrylate ( Polyhydroxyethyl methacrylate), Silicone; Or it may include a combination thereof.

The hydrocolloid particles may further include a cross-linking agent to form the hydrophilic polymer into a three-dimensional network structure. The cross-linking agent is calcium chloride, calcium sulfate, calcium nitrate, and nitric acid. It may be Zinc Nitrate, Zinc Chloride, Zinc Sulfate, Ammonium Persulfate, or Glutaraldehyde. This crosslinking agent is not limited to this and may vary depending on the type of hydrophilic polymer. In one example, the hydrocolloid particles may be alginate crosslinked by calcium ions.

The fabric containing the hydrocolloid may include a hydrophobic elastic polymer. The hydrophobic elastomer may be natural rubber, polyisoprene, polybutadiene, butyl rubber (eg, isoprene and isobutylene copolymer), or halogenated butyl rubber, but is not limited thereto. Specifically, the hydrophobic elastomer may be styrene-isoprene-styrene triblock copolymer (SIS) or a mixture of polyisobutylene and styrene-isoprene-styrene triblock copolymer (SIS).

The fabric containing the hydrocolloid may additionally include an adhesive and/or a plasticizer. The adhesive may be a phenol-modified terpene; Rosin esters, such as glycerol esters of rosin and pentaerythritol esters of rosin; It may include an elastomeric adhesive such as polyisobutylene, a non-elastomeric adhesive including a synthetic polyterpene adhesive, or a combination of two or more thereof. Plasticizers may be used to provide wetting action and/or viscosity control. These plasticizers are well known in the art and include liquid or soft adhesives, waxes, including hydrocarbon oils, liquid hydrocarbon resins, liquid polyterpenes, liquid poly(isobutylene), such as GLISSOPAL, etc. , and oil mixtures. As an example, the plasticizer may be paraffin wax.

The fabric containing the hydrocolloid may additionally include airgel particles. The airgel particles are highly porous nanostructures with nanometer-sized pores obtained by replacing the liquid in the gel structure with air, and may be silica airgel particles.

In one embodiment of the present invention, the sheet 10 having the UV blocking function may include an inorganic UV blocking agent, an organic UV blocking agent, or a combination thereof.

The organic sunscreen includes, but is not limited to, avobenzone (Parsol 1789, butylmethoxydibenzoylmethane), octinoxate (ethylhexylmethoxycinnamate), oxybenzone, homosalate, octocrylene, etc. .

The inorganic sunscreen includes, but is not limited to, titanium dioxide (titanium dioxide) and zinc oxide (zinc oxide).

In one embodiment of the present invention, an adhesive layer 11 is provided on the area where the one or more microneedle patches 20 described above are not attached to the face of both sides of the sheet 10. .

The microneedle patch is inserted into the skin of the face when attaching the mask patch to the face and provides additional adhesion, preventing the mask patch from falling off the skin even when the face sweats due to intense exercise.

The one or more microneedle patches 20 may be attached to one, two, or three or more within the range included in the area of the sheet, but are not limited thereto.

As confirmed in the embodiment of the present invention and in FIG. 1, the sheet 10 with the UV blocking function has a UV blocking rate of 82.1% for UV A (315-400 nm) and 82.1% for UV B according to the KS K 0850 measurement method. (290-315 nm) is very excellent at 99.8%.

In one embodiment of the present invention, the adhesive layer 11, the microneedle patch 20, or a combination thereof is characterized by additionally containing a cosmetic ingredient.

The cosmetic ingredients may be ingredients with various useful functions for the skin, and include, for example, skin moisturizing, skin whitening, skin aging prevention, skin wrinkle improvement, skin barrier protection or recovery, pore care, UV protection, and sebum control. It may be a cosmetic ingredient with a function selected from the group, but is not limited thereto.

In one embodiment of the present invention, the adhesive layer 11, the microneedle patch 20, or a combination thereof may additionally include a cosmetic ingredient with a UV blocking function, so that the sheet with a UV blocking function (10 ) can double the UV blocking effect.

In one embodiment of the present invention, the microneedle patch is made of biodegradable material and has sufficient kurtosis and strength to penetrate the skin. The microneedle patch contains the cosmetic ingredients described above and has the advantage of efficiently delivering the cosmetic ingredients directly into the skin through the microneedle.

The material forming the microneedle patch may swell or dissolve within the skin. Materials forming the microneedle patch include, for example, hyaluronic acid or its salt, carboxymethyl cellulose or its salt, vinylpyrrolidone-vinylacetate copolymer, polyvinyl alcohol, and polyvinylpyrrillidone. water-soluble polymers such as pyrrolidone); Sugars such as xylose, sucrose, maltose, lactose, and trehalose; Or it may include, but is not limited to, a mixture thereof.

In one embodiment of the present invention, the microneedle patch may contain niacinamide and sodium hyaluronate, but is not limited thereto.

In a more specific embodiment of the present invention, the microneedle patch includes niacinamide, and sodium hyaluronate; Includes, but is not limited to, sodium hyaluronate crosspolymer-2, glycerin, trehalose, and minerals.

More specifically, the material forming the microneedle patch is a water-soluble material that can swell or dissolve well in the skin, such as hyaluronic acid or its salt, sodium carboxymethyl cellulose, and polyvinyl. It may include alcohol (poly(vinyl alcohol)), polyvinyl pyrrolidone (poly(vinyl pyrrolidone)), polyacrylate, saccharides, or mixtures thereof.

In addition, the material forming the microneedle patch may additionally include a plasticizer, surfactant, preservative, etc., taking into account the skin penetration strength of the microneedle and the dissolution rate in the skin.

The plasticizer includes, for example, polyols such as ethylene glycol, propylene glycol, dipropylene glycol, butylene glycol, and glycerine. It can be used alone or in combination.

The structure or shape of the microneedle of the present invention is divided from the base to the tip.

Looking at it so far, the width of the base narrows from wide to narrow: a square pyramid shape, a triangular pyramid shape, a combination of a triangular pyramid and a triangular pyramid, a combination of a square pyramid and a square pyramid, a cone shape, a combination of a cone and a truncated cone, and a stepped pyramid. Any shape, including microblade shape or bullet shape, is possible.

The length of the microneedle of the present invention preferably ranges from 20 μm to 1 mm. More specifically, the length is preferably 500 μm or less, 400 μm or less, 300 μm, 290 μm or less, 280 μm or less, 270 μm, 250 μm or less, and the length should be less than 270 μm to avoid pain or uncomfortable irritation during outdoor activities. Do it as

The diameter of the microneedle may be 150 μm or less, 140 μm or less, 130 μm or less, 120 μm or less, 110 μm or less, 100 μm or less, but it must have a diameter of 120 μm or less to avoid pain or discomfort during outdoor activities. It is characterized by no irritation.

The spacing between the microneedles is preferably 1 mm or less, but is not limited thereto.

The microneedle patch of the present invention may be manufactured to include 500 or more, 600 or more, 700 or more, or 800 or more microneedles inside the patch.

The microneedle patch must be manufactured so that there are at least 500 microneedles inside the patch to help improve the adhesion of the fabric to the skin and to effectively deliver skin useful ingredients (cosmetic ingredients) within the microneedles into the skin.

In one embodiment of the present invention, the shape of the UV blocking mask patch 1 may be symmetrical with respect to the user's nose, but is not limited thereto.

In another embodiment of the present invention, the ultraviolet ray blocking mask patch 1 may consist of a separate pair of left and right sides as one set, but is not limited to this.

In one embodiment of the present invention, the ultraviolet ray blocking mask patch (1) is a release paper attached on the microneedle patch and the adhesive layer (11) to protect the microneedle patch (20) and the adhesive layer (11). 30) is additionally provided.

In one embodiment of the present invention, the sheet 10 with the ultraviolet ray blocking function is characterized by being provided with one or more grooves (nicks) 40, 41, 42 around the circumference of the sheet.

In one embodiment of the present invention, the shape of the groove is A gentle form, such as It may have a sharp shape such as, or a combination thereof, but is not limited thereto.

As shown in Figure 2 of the present invention, if there is no groove around the sheet 10, the sheet is in contact with the skin and partially lifted due to the three-dimensional outline of the face.

According to one embodiment of the present invention, the mask patch for blocking ultraviolet rays of the present invention may be manufactured in the form shown in Figure 3, but is not limited thereto. The mask patch having the shape of Figure 3 is manufactured symmetrically around the nose and is attached to the area under the eyes, cheekbones, and cheeks.

In the mask patch as shown in FIG. 3, the grooves formed in the sheet are located on the upper, inner, and outer surfaces centered on the cheekbones. The grooves on the upper and inner surfaces have gentler curves, and the grooves on the outer surfaces have more sharp curves. The shape of the mask patch in FIG. 3 is similar to the shape of a bird's wing, and has excellent aesthetics without forming wrinkles when attached to the face.

Referring to Figure 2 of the present invention, the positions of the lifted portions around the circumference of the sheet occur on the upper, outer, and inner sides centered on the cheekbones. The one or more grooves 40, 41, 42 provided on the periphery of the sheet of the present invention prevent wrinkles from forming when the sheet is attached to the user's face. Since one or more wrinkles occur on the top, outer surface, and inner surface, the number and location of the grooves 40, 41, and 42 also depend on the upper and outer surfaces of the positions where wrinkles occur in the sheet along the circumference of the sheet. , and one or more are preferably provided on the inner side.

A method of using the UV-blocking patch according to an embodiment of the present invention having the above configuration will be described as follows.

First, before using the UV-blocking mask patch 1 according to an embodiment of the present invention, the user removes the release paper 30 that protects the microneedle patch 20 and the adhesive layer 11 of the mask patch described above.

Attach the mask patch 1 with the release paper 30 removed to the desired location. In the case of the mask patch 1 illustrated in FIG. 3 of the present invention, it is attached on the cheekbones and cheeks on both sides of the nose. At this time, the microneedle patch 20 is attached to the face by applying slightly more pressure to the area where the microneedle patch 20 is located so that it can be inserted into the facial skin.

The features and advantages of the present invention are summarized as follows:

The present invention provides a mask patch for blocking ultraviolet rays.

The UV-blocking mask patch of the present invention has excellent UV-blocking effect and is equipped with a microneedle patch, so it has superior adhesive strength compared to a general mask patch and can deliver useful ingredients to the skin.

Figure 1 is a diagram showing the results of a test (KS K 0850:2019) on the UV-blocking efficacy of the fabric at the Korea Apparel Testing & Research Institute to confirm the UV-blocking efficacy of the hydrocolloid fabric of the present invention.
Figure 2 is a diagram showing an example of a microneedle patch attached to the face before introducing anti-wrinkle grooves on the edge of the microneedle patch, as in Example 2 of the present invention.
Figure 3 is a diagram showing an exemplary design in which wrinkle-prevention grooves are introduced at the edge of the microneedle patch in Example 2 of the present invention.

Hereinafter, the present invention will be described in more detail through examples. These examples are only for illustrating the present invention in more detail, and it will be apparent to those skilled in the art that the scope of the present invention is not limited by these examples according to the gist of the present invention. .

Example

Throughout this specification, “%” used to indicate the concentration of a specific substance means (weight/weight) % for solid/solid, (weight/volume) % for solid/liquid, and Liquid/liquid is (volume/volume) %.

Example 1: Preparation of microneedle patch for UV protection

In order to manufacture a microneedle patch that blocks ultraviolet rays, the present inventors used microneedles made of hydrocolloid fabric and biodegradable polymer with excellent ultraviolet ray blocking performance as follows.

1-1. Checking the UV blocking performance of hydrocolloid fabric

The present inventors produced a patch fabric for UV protection using a hydrocolloid fabric containing an inorganic UV blocking agent.

The components of hydrocolloid fabric included hydrophobic polymers, hydrophilic polymers, and sunscreen.

PIB (polyisobutylene) and SIS (styrene-isoprene styrene block copolymer) were used as hydrophobic polymers that make up the fabric, and CMC (Sodium Carboxymethyl Cellulose) was used as the hydrophilic polymer.

Zinc oxide, an inorganic sunscreen, and titanium dioxide were used as sunscreens.

Mineral oil was included to add flexibility to the hydrocolloid fabric, and a rosin ester-based tackifier was used as a tackifier to provide adhesiveness to attach the hydrocolloid fabric to the skin.

In order to confirm the UV blocking efficacy of the hydrocolloid fabric (JY Pharm Co., Ltd.), the UV blocking efficacy of the fabric was tested at the Korea Apparel Testing & Research Institute (KS K 0850:2019). The test results are shown in Figure 1.

As shown in Figure 1, the hydrocolloid fabric of the present invention has a UVA (315-400 nm) blocking rate of 82.1% and a UVB (290-315 nm) blocking rate of 99.8%, showing a very high UV blocking effect. It was confirmed to be excellent.

1-2. Manufacturing of microneedle patch parts

Niacin amide and sodium hyaluronate were used as the main ingredients of the microneedle patch, and additional ingredients included sodium hyaluronate cross polymer-2, glycerin, trehalose, and minerals. . The microneedle portion may contain functional cosmetic raw materials as active ingredients, and in this example, niacin amide was used as a whitening functional cosmetic composition.

The length of the microneedle of the microneedle patch part was 270 μm or less, the diameter of the microneedle was 120 μm or less, and the needle spacing was manufactured to be 1000 μm or less. It was expected that only if the above standards were met would it be possible to deliver skin-useful ingredients to the skin through microneedles without causing pain or discomfort even when engaging in outdoor activities with the microneedles attached to the skin. In the microneedle patch part, the needles were arranged so that there were at least 500 microneedles per patch.

1-3. Adhesion of hydrocolloid fabric and microneedle patch section

The microneedle patch prepared in 1-2 was attached to the hydrocolloid fabric of 1-1.

First, the adhesive surface of the hydrocolloid fabric was protected with release paper or a transparent film, and the release paper or film was removed in the shape of the patch at the location where the microneedle patch was scheduled to be attached, exposing the adhesive surface. The microneedle patch was attached to the hydrocolloid fabric with the adhesive surface exposed.

Example 2: Shape design of hydrocolloid fabric

The present inventors cut the fabric into an inverted triangle shape to block ultraviolet rays by attaching a patch containing a hydrocolloid fabric with ultraviolet ray blocking effect to both (left/right) cheeks and under the eyes around the nose. A microneedle patch with the same configuration as Example 1 was manufactured and attached to the face (see Figure 2). As a result, it was confirmed that due to the curvature of the face surface, floating spaces and wrinkles occurred on the edge of the patch product, reducing the adhesive strength of the entire patch.

Accordingly, in order to improve the above shortcomings, the present inventors introduced a concave groove-shaped design in the middle of the edge of the hydrocolloid fabric. An exemplary design is shown in Figure 3.

As shown in Figure 3, when one or more grooves were introduced to the edge of the product, the occurrence of open spaces or wrinkles on the edge of the patch was significantly reduced.

1: Mask patch for UV protection
10a, 10b: Sheets with UV blocking function
11: Adhesive layer
20a, 20b, 21a, 21b: Microneedle patch
21: Microneedle
30: Release paper or protective film
40a, 40b, 41a, 41b, 42a, 42b: Anti-wrinkle groove

Claims (8)

UV protection mask patch containing:
(a) Sheet with UV protection function;
(b) One or more microneedle patches attached to the side of the sheet in contact with the face.
The mask patch for blocking ultraviolet rays according to claim 1, wherein an adhesive layer is provided on an area of the sheet to which the microneedle patch is not attached.
The mask patch for UV protection according to claim 2, wherein the adhesive layer, the microneedle patch, or a combination thereof additionally contains a cosmetic ingredient.
The cosmetic ingredient according to claim 3, wherein the cosmetic ingredient has a function selected from the group consisting of skin moisturizing, skin whitening, skin aging prevention, skin wrinkle improvement, skin barrier protection or restoration, pore care, ultraviolet ray blocking, and sebum control. In, mask patch for UV protection.
The mask patch for blocking UV rays according to claim 1, wherein the mask patch for blocking UV rays consists of a separate pair of left and right sides as one set.
The mask for blocking ultraviolet rays according to claim 1, wherein the mask patch for blocking ultraviolet rays is additionally provided with a release paper or protective film attached on the microneedle patch and the adhesive layer to protect the microneedle patch and the adhesive layer. patch.
The mask patch for UV protection according to claim 1, wherein the sheet having the UV blocking function includes an inorganic UV blocking agent, an organic UV blocking agent, or a combination thereof.
The mask patch for UV blocking according to claim 1, wherein the sheet with the UV blocking function is provided with one or more anti-wrinkle grooves (nicks) on a circumference of the sheet.