KR20230119301A - Multi-componet simultaneous analysis method utilizing GC and LC - Google Patents
Multi-componet simultaneous analysis method utilizing GC and LC Download PDFInfo
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- KR20230119301A KR20230119301A KR1020220015269A KR20220015269A KR20230119301A KR 20230119301 A KR20230119301 A KR 20230119301A KR 1020220015269 A KR1020220015269 A KR 1020220015269A KR 20220015269 A KR20220015269 A KR 20220015269A KR 20230119301 A KR20230119301 A KR 20230119301A
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- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N2030/022—Column chromatography characterised by the kind of separation mechanism
- G01N2030/025—Gas chromatography
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
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- G01N2030/027—Liquid chromatography
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Abstract
본 발명의 목적은 GC 및 LC를 이용한 다성분 동시분석법을 제공하고자 하는 것으로, 본 발명의 구성은 시료 무게를 측정하는 칭량 단계; 시료를 추출하는 추출 단계; 시료를 분리하는 분배 단계; 시료를 농축하는 농축 단계; 시료에서 불순물을 제거하는 정제 단계; 시료를 기기에 의해 분석하는 기기 분석 단계;를 포함하는것을 특징으로 한다.An object of the present invention is to provide a multi-component simultaneous analysis method using GC and LC, and the configuration of the present invention includes a weighing step of measuring the weight of a sample; An extraction step of extracting a sample; A distribution step of separating the sample; Concentration step of concentrating the sample; A purification step to remove impurities from the sample; Characterized in that it comprises; a device analysis step of analyzing the sample by the device.
Description
본 발명은 시료의 다성분 동시분석법에 관한 것으로, 보다 상세하게는 분석 대상 시료에 대한 GC 및 LC를 이용한 다성분 동시분석법에 관한 것이다.The present invention relates to a multi-component simultaneous analysis method of a sample, and more particularly, to a multi-component simultaneous analysis method using GC and LC for a sample to be analyzed.
일반적으로 가스 크로마토그래피(Gas Chromatography)는 가스 크로마토그래프(Gas Chromatograph)를 이용한 분석법으로 이동상의 기체를 사용하여 혼합기체 시료 성분의 기체 열전도율 차에 의하여 혼합기체 시료를 검출 및 정량하는 기기분석법이다.In general, gas chromatography (Gas Chromatography) is an analysis method using a gas chromatograph. It is an instrumental analysis method for detecting and quantifying a mixed gas sample by using a gas in a mobile phase and using a difference in gas thermal conductivity of the sample components of the mixed gas.
고정상(固定相)의 흡착성을 띄는 고체 분말 미립자를 사용하는 기체-고체 크로마토 그래피와 비활성 고체 분말의 표면에 비휘발성 액체를 보유시킨 기체-액체 크로마토 그래피로 이루어지는데 기체-고체 크로마토 그래피는 끓는점 400 ℃정도에 이르기까지 유기 화합물 전반에 걸쳐 분석가능하며, 기체-액체 크로마토 그래피는 무기 화합물의 기체 및 끓는점이 낮은 탄화수소의 분석에 적합하다.It consists of gas-solid chromatography using adsorbable solid powder microparticles in a stationary phase and gas-liquid chromatography in which a non-volatile liquid is retained on the surface of an inert solid powder. Gas-solid chromatography has a boiling point of 400 ℃ Gas-liquid chromatography is suitable for the analysis of gases of inorganic compounds and low-boiling hydrocarbons.
본 발명의 목적은 물, 환경 및 첨단 소재에 포함된 극미량의 중금속을 분석하는 것과 같은 다양한 분야에서의 시료를 분석하는 방법을 제공하고자 하는 것으로 특히 분석 대상 시료에 대한 GC 및 LC를 이용한 다성분 동시분석법을 제공하고자 하는 것이다.An object of the present invention is to provide a method for analyzing samples in various fields, such as analyzing trace amounts of heavy metals contained in water, the environment, and advanced materials. It is to provide an analysis method.
본 발명에 의하면, 시료 무게를 측정하는 칭량 단계; 시료를 추출하는 추출 단계; 시료를 분리하는 분배 단계; 시료를 농축하는 농축 단계; 시료에서 불순물을 제거하는 정제 단계; 시료를 기기에 의해 분석하는 기기 분석 단계;를 포함하는 GC 및 LC를 이용한 다성분 동시분석법이 제공된다.According to the present invention, the weighing step of measuring the weight of the sample; An extraction step of extracting a sample; A distribution step of separating the sample; Concentration step of concentrating the sample; A purification step to remove impurities from the sample; There is provided a multi-component simultaneous analysis method using GC and LC, including; instrumental analysis step of analyzing the sample by the instrument.
본 발명은 균질화된 시료를 분취하여 칭량, 분배, 농축, 정제 및 분석 단계를 거쳐서 시료를 GC 및 LC를 이용한 다성분 동시분석법을 채용함으로써, 분석결과의 정밀도를 향상시킬 수 있고, 분석시간이 짧아지고 분석과정이 간단하고 효율적으로 수행되는 효과가 있다.The present invention adopts a multi-component simultaneous analysis method using GC and LC for the sample after taking a homogenized sample and passing through the steps of weighing, distribution, concentration, purification and analysis, thereby improving the accuracy of the analysis result and reducing the analysis time. This has the effect of making the analysis process simple and efficient.
도 1은 GC 및 LC를 이용한 다성분 동시분석법의 분석 과정을 개략적으로 보여주는 도면이다.1 is a diagram schematically showing an analysis process of a multi-component simultaneous analysis method using GC and LC.
본 발명은 시료 무게를 측정하는 칭량 단계; 시료를 추출하는 추출 단계; 시료를 분리하는 분배 단계; 시료를 농축하는 농축 단계; 시료에서 불순물을 제거하는 정제 단계; 시료를 기기에 의해 분석하는 기기 분석 단계;를 포함하는 GC 및 LC를 이용한 다성분 동시분석법이다.The present invention weighing step of measuring the weight of the sample; An extraction step of extracting a sample; A distribution step of separating the sample; Concentration step of concentrating the sample; A purification step to remove impurities from the sample; It is a multi-component simultaneous analysis method using GC and LC, including; an instrumental analysis step of analyzing a sample by an instrument.
본 발명에서는 균질화된 시료를 분취하여 아세토니트릴을 이용 추출하고 염을 첨가하여 혼합하여 유기용매층을 취하여 SPE Cartridge로 정제하여 기체 및 액체 크라마토그래피로 분석한다.In the present invention, the homogenized sample is collected, extracted using acetonitrile, salt is added and mixed, and the organic solvent layer is taken, purified with an SPE cartridge, and analyzed by gas and liquid chromatography.
분배 단계에서는 원심분리기를 이용하여 분리한다.In the distribution step, it is separated using a centrifuge.
농축 단계에서는 질소 농축을 한다.In the concentration step, nitrogen concentration is performed.
기기 분석 단계에서는 LC 및 CG를 이용하여 분석한다.In the instrumental analysis step, analysis is performed using LC and CG.
Claims (1)
시료를 추출하는 추출 단계;
시료를 분리하는 분배 단계;
시료를 농축하는 농축 단계;
시료에서 불순물을 제거하는 정제 단계;
시료를 기기에 의해 분석하는 기기 분석 단계;를 포함하는 GC 및 LC를 이용한 다성분 동시분석법.Weighing step of measuring the weight of the sample;
An extraction step of extracting a sample;
Dispensing step of separating the sample;
Concentration step of concentrating the sample;
A purification step to remove impurities from the sample;
Multi-component simultaneous analysis method using GC and LC, including; instrumental analysis step of analyzing the sample by the instrument.
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| KR1020220015269A KR20230119301A (en) | 2022-02-07 | 2022-02-07 | Multi-componet simultaneous analysis method utilizing GC and LC |
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| KR1020220015269A KR20230119301A (en) | 2022-02-07 | 2022-02-07 | Multi-componet simultaneous analysis method utilizing GC and LC |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100357317B1 (en) | 1999-09-29 | 2002-10-19 | 이계호 | Sample Introduction Device and Sample Analysis Method using thereof |
| KR101099495B1 (en) | 2008-10-14 | 2011-12-28 | 삼성전자주식회사 | Centrifugal force-based microfluidic device, method of manufacturing the same and sample analysis method using the same |
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- 2022-02-07 KR KR1020220015269A patent/KR20230119301A/en unknown
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100357317B1 (en) | 1999-09-29 | 2002-10-19 | 이계호 | Sample Introduction Device and Sample Analysis Method using thereof |
| KR101099495B1 (en) | 2008-10-14 | 2011-12-28 | 삼성전자주식회사 | Centrifugal force-based microfluidic device, method of manufacturing the same and sample analysis method using the same |
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