KR20230106439A - Bubble separator and optical analysis apparatus with The Same - Google Patents

Abstract

The present invention relates to a bubble separator apparatus, which is able to effectively separate bubbles included in an analysis subject through the optimal instrumental design for separating bubbles, and an optical analysis apparatus including the same. According to the present invention, the bubble separator apparatus comprises: a spiral-shaped flow path extended upward for a certain radius from a vertical axis; an input flow path branched in a shape of being extended downward from a point of the spiral-shaped flow path; a bubble discharge flow path branched in a shape of being extended upward from a point of the spiral-shaped flow path; an analysis sample flow path branched downward from a point of the spiral-shaped flow path and connected to an analysis sample chamber; and the analysis sample chamber storing an analysis sample transmitted through the analysis sample flow path. A liquid analysis subject including bubbles is moved upward along the spiral-shaped flow path by being introduced into the spiral-shaped flow path through one end of the spiral-shaped flow path and the input flow path, and the bubbles included in the analysis subject are discharged through the bubble discharge flow path. An analysis sample, which is the analysis subject from which bubbles are separated, is moved to the analysis sample chamber through the analysis sample flow path.

Description

Bubble separator and optical analysis apparatus including the same {Bubble separator and optical analysis apparatus with The Same}

The present invention relates to a bubble separator and an optical analysis device including the same, and more particularly, to a bubble separator capable of effectively separating bubbles contained in an analysis object through an optimal mechanical design for bubble separation, and the same. It relates to an optical analysis device comprising

Gas-liquid reactions in which gaseous and liquid substances are mixed, such as biotransformation, hydrogenation, and halogenation, are used in various industrial fields, and research is being actively conducted to improve the reaction efficiency. It is becoming.

In order to study the reaction efficiency of the gas-liquid reaction, it is necessary to analyze materials in the gas-liquid reactor, such as starting materials or reaction products. Chromatographic analysis is generally widely used for this analysis. Chromatographic analysis is a method of sampling an analyte and analyzing it through a chromatography device. However, contamination of the gas-liquid reactor may occur during the sampling process, and it is difficult to apply in terms of analysis automation.

Recently, a method of directly analyzing materials in a gas-liquid reactor in real time by installing a spectrometer in a gas-liquid reactor has been attempted. This method does not require a process of sampling an analyte and moving the sampled analyte to a separate analysis device, and thus can solve various problems caused by sampling. However, in analyzing an analyte in the gas-liquid reactor by mounting an optical analysis device such as a spectrometer in a gas-liquid reactor, if bubbles exist in the analyte, scattering occurs due to the bubbles, and the optical signal of the optical analysis device interferes. and the interference of optical signals caused by these bubbles deteriorates the reliability of the analysis.

In order to solve this problem, Japanese Unexamined Patent Publication No. 2001-9268 allows a sample to be supplied from the reaction tank 2 to the defoaming measuring cell 1, and high-pressure nitrogen gas is supplied through the pressure source 5 to the defoaming measuring cell ( 1) suggests a technique for removing air bubbles contained in the sample in the defoaming measuring cell 1 by supplying the air bubbles to the sample. In addition, Japanese Patent Publication No. 5843284 discloses that a pipe 21 connected to a pump 22 is disposed in the notch part K1 of the optical probe 11 of the spectrometer, and the optical probe 11 is connected to the pump 22. ) Suggests a technique of removing the air bubbles (B) by spraying the solution (S) to the notch portion (K1).

However, the technologies described in the above-mentioned patents require a device for supplying a high-pressure gas, or require a separate process for an optical probe and installation of a pump.

Japanese Unexamined Patent Publication No. 2001-9268 (published on January 16, 2001) Japanese Patent Publication No. 5843284 (issued on January 13, 2016)

The present invention has been made to solve the above problems, and provides a bubble separator capable of effectively separating bubbles contained in an object of analysis through an optimal mechanical design for bubble separation and an optical analysis device including the same. Its purpose is to provide

A bubble separator according to the present invention for achieving the above object includes a spiral passage extending upward at a predetermined radius with respect to a vertical axis; An inflow passage branched in a form extending downward from one point of the spiral passage; A bubble discharge passage branched in a form extending upward from one point of the spiral passage; an analysis sample flow path branching downward from a point of the spiral flow path and connected to the analysis sample chamber; and an analysis sample chamber for storing the analysis sample transferred through the analysis sample passage, wherein the liquid-phase analyte containing bubbles flows into the spiral passage through one end of the spiral passage and the inlet passage, and flows along the spiral passage. It is characterized in that the air bubbles included in the analysis object are discharged through the air bubble discharge passage, and the analysis sample, which is the analysis object from which the air bubbles are separated, is moved to the analysis sample chamber through the analysis sample passage.

A point where the inflow passage is coupled to the spiral passage and a point where the bubble discharge passage is coupled to the spiral passage are spaced apart from each other and sequentially disposed on the spiral passage.

The inflow passage and the bubble discharge passage form a pair and are spaced apart along the spiral passage and repeatedly arranged a plurality of times.

It further includes a probe mounting member and a carrier, wherein a space for the spiral passage, an inflow passage, a bubble discharge passage, an analysis sample passage, and an analysis sample chamber is formed in the carrier, and an optical analysis device is formed on one side of the probe mounting member. A probe mounting space having a shape corresponding to the probe is provided, and the probe mounting member is selectively detachable.

In addition, the bubble separator according to the present invention includes a probe mounting member having a probe mounting portion to which a probe of an optical analysis device is mounted; and an analysis sample storage member having an analysis sample storage space in which an analysis sample is stored, wherein when the probe mounting member and the analysis sample storage member are coupled, an analysis sample storage space is provided at the bottom of the probe mounting unit, and the probe mounting unit Another feature is that a bubble discharge passage and an analysis sample passage are formed around the .

At least one inlet is provided along the upper circumference of the analysis sample storage member, through which the analysis target is introduced, and a bubble outlet through which air bubbles separated from the analysis target are discharged is provided on the upper surface of the probe mounting member, and the inlet of the analysis sample storage member is provided. When the liquid analyte is introduced into the inner space of the bubble separator through this process, the bubbles contained in the analyte are moved upward along the bubble discharge passage by buoyancy, and the analyte sample from which the bubbles are separated moves along the analyte sample passage. The air bubbles moved downward and upward along the bubble discharge passage are discharged to the outside of the bubble separator through the bubble outlet provided on the upper surface of the probe mounting member, and the analysis sample moved downward along the analysis sample passage is disposed at the bottom of the probe mounting portion. It is stored in the provided space, the analysis sample storage space.

The probe mounting portion of the probe mounting member has a shape in which a cylinder of a certain length extends downward, and the length of the probe mounting portion is longer than the height of the probe mounting member, so that when the probe mounting member and the analysis sample storage member are coupled, a portion of the probe mounting portion is covered with the sample to be analyzed. It is located in the inner space of the storage member.

An optical analysis device according to the present invention is characterized in that a bubble separator is mounted on a probe for applying an optical signal.

The bubble separation device and the optical analysis device including the same according to the present invention have the following effects.

When the analyte in the reactor is directly analyzed through the optical analysis device, air bubbles contained in the analyte are effectively separated from the analysis sample, thereby preventing degradation of analysis reliability due to air bubbles.

1 is a perspective view of a bubble separator according to a first embodiment of the present invention.
2 is a plan view of a bubble separator according to a first embodiment of the present invention.
Figure 3 is a reference diagram for explaining the bubble separation process of the bubble separator according to the first embodiment of the present invention.
4 is a configuration diagram of the bubble separator according to the first embodiment including a probe mounting member and a carrier.
5 is a perspective view of a bubble separator according to a second embodiment of the present invention.
6 is a cross-sectional view taken along line AA` of FIG. 5;
7 is a reference view for explaining the bubble separation process of the bubble separator according to the second embodiment of the present invention.
Figure 8 is a reference diagram showing the bubble separation simulation results of the comparison group.
FIG. 9 is a reference view showing simulation results of bubble separation of the bubble separator according to the first embodiment of the present invention.
FIG. 10 is a reference view showing simulation results of bubble separation of the bubble separator according to the first embodiment of the present invention.
11 is a result of analyzing dissolved carbon monoxide by a surface-enhanced Raman spectrometer when a comparative group is applied.
12 is a result of analyzing dissolved carbon monoxide by a surface-enhanced Raman spectrometer when a bubble separator according to the first embodiment, a bubble separator according to the second embodiment, and a comparative group are respectively applied.
13 is a photograph showing that a probe coupled with a bubble separator according to a second embodiment of the present invention is coupled to a gas-liquid reactor.

The present invention proposes a technique capable of improving the reliability of analysis of an analyte by separating air bubbles present in the analyte in real-time analysis of the analyte in the reactor using an optical analysis device.

An optical analysis device that analyzes the components of an analysis object using optical signals, such as a spectrometer, is a device that applies an optical signal such as near infrared rays to a liquid analysis object and analyzes the received signal to perform quantitative and qualitative analysis on the analysis object. am.

As mentioned above in the 'Background of the Invention', this optical analysis device is mounted on a gas-liquid reactor and used for real-time analysis of an analyte in the gas-liquid reactor, and to improve analysis reliability, It is necessary to separate air bubbles. In addition, in the case of Patent Documents 1 and 2, a technique for separating air bubbles in an object to be analyzed is presented, but there is a problem in that a device for supplying a high-pressure gas and a separate processing for an optical probe are required.

In the present invention, a bubble separation device having a predetermined mechanical structure is coupled to a probe of an optical analysis device immersed in a liquid analyte, so that an optical analysis is performed on an analysis sample from which bubbles are separated, thereby forming bubbles. We propose a technique that can effectively prevent the degradation of analysis reliability caused by

The bubble separator mounted on the probe of the optical analysis device allows the analyte to flow into the bubble separator in a state of being immersed in the liquid phase analyte in the reactor, separates the bubbles from the analyte, and analyzes the sample from which the bubbles are separated. Choose a way to fill the sample chamber.

Hereinafter, a bubble separator according to the first and second embodiments of the present invention and an optical analysis device including the same will be described in detail with reference to the drawings.

1 to 3, the bubble separator according to the first embodiment of the present invention includes a spiral flow path 110, an inlet flow path 120, a bubble discharge flow path 130, an analysis sample chamber 150, and an analysis sample It is made including a flow path 140.

The spiral passage 110 has a shape extending upward at a predetermined radius with respect to a vertical axis. A liquid analyte is introduced into the reactor from one end 111 of the spiral passage 110, and the analyte moves upward along the spiral passage 110 and is discharged through the other end 112 of the spiral passage 110.

The inflow passage 120 and the bubble discharge passage 130 are provided in a branched form at one point of the spiral passage 110 . The inflow passage 120 extends downward from one point of the spiral passage 110 , and the bubble discharge passage 130 extends upward from one point of the spiral passage 110 . Therefore, the inflow passage 120 induces an upward inflow of the analyte into the spiral passage 110, and the bubble discharge passage 130 induces the upward discharge of the analyte containing bubbles from the spiral passage 110. .

In terms of the point at which the bubble discharge passage 130 is coupled to the spiral passage 110, the point at which the bubble discharge passage 130 is coupled to the spiral passage 110 is spaced from the point at which the inflow passage 120 is coupled to the spiral passage 110 to the rear end. located in That is, a point where the inflow passage 120 is coupled to the spiral passage 110 and a point where the bubble discharge passage 130 is coupled to the spiral passage 110 are spaced apart from each other on the spiral passage 110 and are sequentially arranged.

In addition, the inflow passage 120 and the bubble discharge passage 130 form a pair and are repeatedly arranged at regular intervals along the spiral passage 110 . The reason for arranging a plurality of pairs of the inflow passage 120 and the bubble discharge passage 130 along the spiral passage 110 is to continuously discharge the bubbles moving along the spiral passage 110, and the bubbles are coupled to each other. This is to facilitate the discharge of bubbles by inducing it to become. The bubbles moving upward along the spiral passage 110 are combined with each other in the process of moving, and the size of the bubbles increases. As the size of the bubbles increases, the buoyancy increases, so that they can be easily discharged through the bubble discharge passage 130. .

In this way, the analyte introduced through one end of the spiral passage 110 and the plurality of inflow passages 120 is moved upward along the spiral passage 110, and during the upward movement, the bubbles contained in the analyte are air bubbles. Discharged through the discharge passage 130 , the analysis object from which bubbles are separated, that is, the analysis sample is moved to the analysis sample chamber 150 via the analysis sample passage 140 .

The analysis sample flow path 140 branches from the spiral flow path 110 and is connected to the analysis sample chamber 150, and the analysis sample, which is an analysis object separated from the air bubbles in the spiral flow path 110, is moved to the analysis sample chamber 150. induce that The analysis sample flow path 140 forms a downward branching shape at one point of the spiral flow path 110, which is to prevent the analysis sample from containing air bubbles by allowing the analysis sample to move downward. Such an analysis sample passage 140 may also be repeatedly arranged at regular intervals along the spiral passage 110 . However, as the bubble separation process must proceed to a certain level, it is preferable that the analysis sample passage 140 is provided at the upper end of the spiral passage 110.

Briefly summarizing the above description, in a state in which the bubble separation device is immersed in the liquid analyte, the analyte containing the bubbles is disposed at one end of the spiral flow path 110 and along the spiral flow path 110. is introduced into the spiral passage 110 through the spiral passage 110, and the analyzed object moves upward along the spiral passage 110, and in the process of the upward movement of the analysis object, bubbles are combined with each other to separate the bubbles through the bubble discharge passage 130. The analyte, i.e., the analysis sample, which is discharged out of the device and air bubbles are separated, moves from the spiral passage 110 to the analysis sample chamber 150 through the analysis sample passage 140 branched downward. Through this process, an analysis sample from which bubbles are removed can be obtained, and optical analysis can be performed on the analysis sample.

For reference, the analyte in the reactor is in a state of being agitated by an agitator, so that a separate power source, such as a pump, is not required when the analyte is introduced into the bubble separator.

Meanwhile, the aforementioned spiral passage 110, inlet passage 120, bubble discharge passage 130, analysis sample passage 140, and analysis sample chamber 150 may be formed in the carrier 10 (FIG. 4). reference). In one embodiment, the space of the spiral flow path 110, the inlet flow path 120, the bubble discharge flow path 130, the analysis sample flow path 140 and the analysis sample chamber 150 inside the cylindrical carrier 10 is It can be configured in a dug form. In this case, only one end and the other end of the spiral passage 110, the inlet of the inflow passage 120, and the outlet of the bubble discharge passage 130 are exposed to the outside of the carrier 10. As the material of the carrier 10, polymers, ceramics, metals, stainless steel, etc. may be used. When the carrier 10 is made of polymers, any one of PDMS, PMMA, PET, PE, PP, and hydrogel may be used. can

In addition, the bubble separator according to the present invention additionally has a structure capable of being detached from the probe of the optical analysis device for convenience during analysis by the optical analysis device.

Specifically, as shown in FIG. 4 , a bubble separator may be formed by a combination of the probe mounting member 20 and the carrier 10 . As described above, the carrier 10 is formed with spaces for the spiral passage 110, the inlet passage 120, the bubble discharge passage 130, the analysis sample passage 140, and the analysis sample chamber 150, and the probe The mounting member 20 is a member coupled to the carrier 10 as well as having a space in which the probe of the optical analysis device is mounted.

In one embodiment, both the probe mounting member 20 and the carrier 10 may have a cylindrical shape, and the probe mounting member 20 and the carrier 10 may be screwed together. At this time, a probe mounting space 21 having a shape corresponding to the probe is provided on one side of the probe mounting member 20, and the probe P is mounted in the probe mounting space 21 of the probe mounting member 20. The bubble separation device according to the first embodiment of the present invention can be coupled to the probe of the optical analysis device by screwing the probe mounting member 20 and the carrier 10 in .

In this way, in a state where the bubble separator is coupled to the probe of the optical analysis device, the bubble separator is immersed in the object to be analyzed in the reactor, and the analysis sample from which bubbles are separated through the bubble separation process of the bubble separator is analyzed by the bubble separator. By inducing movement into the sample chamber and then applying an optical signal to the analysis sample through the probe, component analysis of the analysis sample can be performed by the optical analysis device.

In the above, the bubble separator according to the first embodiment of the present invention has been described. Next, a bubble separator according to a second embodiment of the present invention will be described.

5 to 7, the bubble separator according to the second embodiment of the present invention includes a probe mounting member 210 and an analysis sample storage member 220.

The probe mounting member 210 and the analysis sample storage member 220 are coupled to each other at the upper and lower positions, respectively. In one embodiment, the analysis sample storage member 220 has a cylindrical or bowl shape, and the probe mounting member 210 has a lid shape to seal the inner space of the analysis sample storage member 220, and the analysis sample storage member 220 coupled to

Both the probe mounting member 210 and the analysis sample storage member 220 have hollow insides, and in the case of the probe mounting member 210, a probe in which the probe of the optical analysis device is mounted in the center of the probe mounting member 210. A mounting portion 211 is provided.

The probe mounting portion 211 of the probe mounting member 210 has a shape in which a cylinder of a certain length extends downward, and the length of the probe mounting portion 211 is longer than the height of the probe mounting member 210 and the probe mounting member 210 When the analysis sample storage member 220 is coupled, a portion of the probe mounting portion 211 is located in the inner space of the analysis sample storage member 220 .

When the probe mounting member 210 and the analysis sample storage member 220 are coupled, a space defined by the probe mounting member 210, the analysis sample storage member 220, and the probe mounting portion 211 is formed, and the probe mounting portion ( 211) is located at the center of the probe mounting member 210, it can be spatially divided into a space of the probe mounting part 211, which is an independent space, and a space other than that.

The space other than the probe mounting portion 211 is divided into a space under the probe mounting portion 211 and a space around the probe mounting portion 211 . A space under the probe mounting unit 211 is a space in which analysis samples are stored, and a space around the probe mounting unit 211 is a space in which air bubbles are separated from the analyte. Here, the space below the probe mount 211, that is, the space where the analysis sample is stored will be referred to as the 'analysis sample storage space 221'. In addition, the space around the probe mounting part 211, that is, the space in which bubbles are separated from the analysis object is called a 'bubble discharge passage 231' at the top and 'analysis sample passage 232' at the bottom.

For the separation of air bubbles and the movement of the analysis sample, a plurality of inlets 222 are spaced apart along the circumference on the upper side of the analysis sample storage member 220, and a plurality of air bubble outlets ( 212) is provided.

Under such a structure, when the liquid-type analyte is introduced into the inner space of the bubble separator through the inlet 222 of the analysis sample storage member 220, the bubbles contained in the analyte are buoyant to the bubble discharge passage 231. The analysis object, that is, the analysis sample from which air bubbles are separated is moved downward along the analysis sample passage 232. As described above, the space other than the probe mounting portion 211, that is, the space around the probe mounting portion 211, is divided into a bubble discharge passage 231 at the top and an analysis sample passage 232 at the bottom.

The bubbles moved upward along the bubble discharge passage 231 are discharged to the outside of the bubble separator through the bubble outlet 212 provided on the upper surface of the probe mounting member 210, and the bubbles moved downward along the analysis sample passage 232 The analysis sample is stored in the analysis sample storage space 221, which is a space provided under the probe mounting part 211.

In the state where the analysis sample is stored in the analysis sample storage space 221 by such a bubble separation process, when an optical signal is applied to the analysis sample through the probe mounted on the probe mounting portion 211, component analysis of the analysis sample is possible. .

For reference, FIG. 13 is a photograph showing that a probe coupled with a bubble separator according to a second embodiment of the present invention is coupled to a gas-liquid reactor.

In the above, the bubble separator according to the first and second embodiments of the present invention has been described. Hereinafter, the present invention will be described in more detail through experimental examples.

<Experimental Example 1: Bubble Separation Simulation>

A bubble separation simulation was performed for each of the bubble separator according to the first embodiment, the bubble separator according to the second embodiment, and the comparative group. In the comparative group, the cylindrical chamber into which the analysis sample was introduced was equipped with only an inlet, and the diameters of the inlet were 2 cm and 0.4 cm, respectively.

Looking at the simulation results for the comparative group (see FIG. 8), it can be seen that a significant amount of air bubbles flow into the cylindrical chamber when the diameter of the inlet is 2 cm, and when the diameter of the inlet is 0.4 cm, the amount of air bubbles inside the cylindrical chamber is confirmed. Although the fraction is low, it can be seen that the concentration difference between the inside and outside of the cylindrical chamber is large at 63%.

Looking at the simulation results for the bubble separator according to the first embodiment (see FIG. 9), the bubble fraction at the inflow passage side was 0.128, while the bubble fraction at a point in the spiral passage at the rear end of the bubble discharge passage was 0.001, and most of the bubbles were present. separation can be confirmed. In addition, in the case of the inside of the analysis sample chamber, it can be seen that the bubble fraction is 0.000, and the air bubbles are completely removed, and it can be seen that there is almost no difference in concentration between the inside and outside of the analysis sample chamber.

Looking at the simulation results of the bubble separator according to the second embodiment (see FIG. 10), it can be confirmed that almost no bubbles exist in the analysis sample storage space.

<Experimental Example 2: Analysis of dissolved carbon monoxide>

Dissolved carbon monoxide of the object to be analyzed was analyzed in a state in which the bubble separator according to the first embodiment, the bubble separator according to the second embodiment, and the comparative group were each coupled to a surface-enhanced Raman spectrometer.

When the comparison group was applied, as shown in FIG. 11, it can be seen that the Raman signal increases until 60 minutes and then decreases, which is due to the interference of the Raman signal due to bubbles. On the other hand, when the bubble separator according to the first embodiment and the bubble separator according to the second embodiment are applied, it can be seen that the signal of dissolved carbon monoxide is not reduced as shown in FIG. 12 .

Through these results, when the air bubble separator according to the first and second embodiments of the present invention is applied, air bubbles are effectively separated from the analysis sample, and thus, it is possible to prevent degradation of analysis reliability due to air bubbles. Able to know.

10: carrier 20: probe mounting member
21: probe mounting member
110: spiral flow path 120: inlet flow path
130: bubble discharge flow path 140: analysis sample flow path
150: analysis sample chamber
210: probe mounting member 211: probe mounting portion
212: bubble outlet 220: analysis sample storage member
221: analysis sample storage space 222: inlet
231: bubble discharge flow path 232: analysis sample flow path

Claims (8)

A spiral passage extending upward at a predetermined radius with respect to a vertical axis;
An inflow passage branched in a form extending downward from one point of the spiral passage;
A bubble discharge passage branched in a form extending upward from one point of the spiral passage;
an analysis sample flow path branched downward from a point of the spiral flow path and connected to the analysis sample chamber; and
An analysis sample chamber for storing the analysis sample delivered through the analysis sample passage;
A liquid analyte containing bubbles is introduced into the spiral passage through one end of the spiral passage and the inflow passage and moves upward along the spiral passage, and the bubbles contained in the analyte are discharged through the bubble discharge passage. The analysis object, the analysis sample, is moved to the analysis sample chamber through the analysis sample passage.
The bubble separator according to claim 1, wherein a point where the inflow passage is coupled to the spiral passage and a point where the bubble discharge passage is coupled to the spiral passage are spaced apart from each other and sequentially disposed on the spiral passage.
The bubble separator according to claim 1, wherein the inflow passage and the bubble discharge passage form a pair and are spaced apart along the spiral passage and repeatedly arranged a plurality of times.
The method of claim 1, further comprising a probe mounting member and a carrier,
Spaces for the spiral passage, the inflow passage, the bubble discharge passage, the analysis sample passage, and the analysis sample chamber are formed in the carrier,
A probe mounting space having a shape corresponding to the probe of the optical analysis device is provided on one side of the probe mounting member,
The bubble separator, characterized in that the probe mounting member is selectively detachable.
a probe mounting member having a probe mounting portion to which a probe of an optical analysis device is mounted; and
An analysis sample storage member having an analysis sample storage space in which the analysis sample is stored;
When the probe mounting member and the analysis sample storage member are coupled, an analysis sample storage space is provided under the probe mounting portion, and a bubble discharge passage and an analysis sample passage are formed around the probe mounting portion.
The method of claim 5, wherein at least one inlet through which the analysis target is introduced is provided along the circumference of the upper end of the analysis sample storage member, and a bubble outlet through which air bubbles separated from the analysis object are discharged is provided on the upper surface of the probe mounting member,
When the liquid analyte flows into the inner space of the bubble separator through the inlet of the sample storage member, the bubbles contained in the analyte are moved upward along the bubble discharge passage by buoyancy, and the bubbles are separated from the analyte. The sample is moved downward along the analysis sample flow path,
The air bubbles moved upward along the bubble discharge passage are discharged to the outside of the bubble separator through the bubble outlet provided on the upper surface of the probe mounting member, and the analysis sample moved downward along the analysis sample passage is a space provided at the bottom of the probe mounting portion. Bubble separation device, characterized in that stored in the analysis sample storage space.
The probe mounting portion of claim 5, wherein the probe mounting portion of the probe mounting member has a shape in which a cylinder of a certain length extends downward, and the length of the probe mounting portion is longer than the height of the probe mounting member when the probe mounting member and the analysis sample storage member are coupled. A part of the region of the bubble separator, characterized in that located in the inner space of the analysis sample storage member.
An optical analysis device, characterized in that the bubble separator according to any one of claims 1 to 8 is mounted on a probe for applying an optical signal.

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