KR20230042607A - Cover type Temperature Maintenance System for Pen Type Injection Appartus - Google Patents

Abstract

The present invention relates to a cover-type temperature maintenance system (100) for a pen-type injection device (10), and more specifically, to a cover-type temperature maintenance system (100) for a pen-type injection device (10) which comprises: a cover main body (110) covering a drug cartridge (11) and detachably mounted on the pen-type injection device (10); a phase change material refrigerant (120) installed inside the cover main body (110); a temperature control means (130) installed on the phase change material refrigerant (120); and a temperature control unit (140) controlling the operation of the temperature control means (130) to maintain the temperature of the phase change material refrigerant (120) at a predetermined set temperature according to the temperature measured by an internal temperature sensor (141) installed in the inside of the cover main body (110). According to the present invention, it is possible to provide the temperature maintenance system (100) for the pen-type injection device (10) which continuously measures and manages the temperature of the drug cartridge (11) and can be managed in conjunction with a smart device or warn of temperature abnormalities.

Description

Cover type temperature maintenance system for pen type injection apparatus {Cover type Temperature Maintenance System for Pen Type Injection Appartus}

The present invention relates to a cover-type temperature maintaining system for a pen-type injection device, which covers a drug cartridge 11 and includes a cover main body 110 detachably mounted to the pen-type injection device 10; and the cover main body 110 A phase change material coolant 120 installed inside; and a temperature control means 130 installed in the phase change material coolant 120; and an inner temperature sensor 141 installed inside the cover body 110 a temperature controller 140 for controlling the operation of the temperature control means 130 so that the temperature of the phase change material coolant 120 maintains a predetermined set temperature Ts according to the temperature measured in; It relates to a cover-type temperature maintenance system 100 of a pen-type injection device, characterized in that configured to include.

In general, in order to periodically self-administer liquid drugs at any time during daily life for various purposes such as treatment of diabetic metabolic disease (diabetes) or weight loss, a disposable portable injection device (e.g., Solostar® insulin injections from Sanofi) Reusable handheld injection devices that can be used with interchangeable pens, ) or cartridges (eg Novo Nordisk's Flexpen® insulin injection pen) are being utilized. In addition, there is also a portable injection device that is automatically operated after setting an input amount, such as "Pen-type portable insulin injection device (Registered Patent No. 10-1217147)" of Patent Document 1 below.

Such a portable injection device is commonly referred to as a "pen-type injection device", and has advantages such as simple and convenient injection while going out compared to general syringes, and enabling injection of an accurate amount with a simple operation.

On the other hand, in the case of insulin-type drugs or drugs for weight loss, since they mainly contain high molecular compounds, it is important to maintain an appropriate temperature (2°C to 24°C) during storage and carrying. In general, in the case of storage, it is stored using a refrigerator or the like, but there are many difficulties in storing it while maintaining an appropriate temperature when carrying it. As a prior invention for cold storage when carrying such an injection drug, the "portable refrigerated drug storage device (Korean Patent Registration No. 10-1637003)" of Patent Document 2, which can accommodate the object to be refrigerated inside, A main body in which a space is provided and a refrigerant is filled in the inner wall while forming a double wall of inner and outer walls; And a cover coupled to the upper part of the main body; Including, a vacuum unit is provided between the inner wall and the outer wall, an exposed surface is provided on one side of the inner wall, a thermometer corresponding to the exposed surface is coupled to the exposed surface, and a cross, circular, square A hole of any one type selected from the following is provided, the inner surface of the hole is finished with silicon, the main body and the cover are made of stainless steel, and all connection parts of the main body and the cover are kept confidential by a sealing member. A configuration related to a portable refrigerated medicine storage device characterized in that being is disclosed.

However, this portable refrigerated drug storage device is simply a configuration using insulation and refrigerant, and cannot be used for long-term storage, and it is fundamentally impossible to maintain a constant temperature such as the temperature of the drug gradually rising over time. there was a problem with that.

1. Republic of Korea Patent No. 10-1217147 2. Republic of Korea Patent No. 10-1637003

The present invention solves the above problems of the existing invention, and efficiently minimizes the change in temperature within a predetermined storage temperature range even for a long time while efficiently using as little power as possible through a combination of a phase change material and a temperature control means. An object of the present invention is to provide a cover-type temperature maintenance system for a pen-type injection device capable of continuously maintaining a constant temperature of a drug cartridge of a pen-type injection device while maintaining a constant temperature.

In addition, it is an object of the present invention to provide a cover-type temperature maintenance system for a pen-type injection device capable of continuously measuring and managing the temperature of a drug cartridge and managing it in conjunction with a smart device or warning of an abnormal temperature.

In order to achieve the above object, the cover-type temperature maintaining system of the pen-type injection device of the present invention covers the drug cartridge 11 and includes a cover body 110 detachably mounted to the pen-type injection device 10; A phase change material coolant 120 installed inside the cover body 110; and a temperature control means 130 installed in the phase change material coolant 120; and a temperature installed inside the cover body 110. A temperature control unit 140 for controlling the operation of the temperature control means 130 so that the temperature of the phase change material coolant 120 maintains a predetermined set temperature Ts according to the temperature measured by the sensor 141; It is characterized in that it is configured to include.

In addition, an ultraviolet ray disinfection means 170 installed inside the cover body 110 to irradiate the injection needle mounted on the drug cartridge 11; Characterized in that it is configured to further include.

In addition, a wireless communication unit 160 connected to the temperature controller 140 and wirelessly transmitting data including the temperature measured by the temperature sensor 141 to an external terminal 200; It is configured to further include, and the external terminal 200 performs a notification function when the temperature measured by the temperature sensor 141 is out of a predetermined temperature range or more while managing a history of the temperature measured by the temperature sensor 141. to be characterized

In addition, a mounting sensor 111 for detecting whether the cover body 110 is mounted on the pen-type injection device 10; It is configured to further include, and the temperature control unit 140 is characterized in that it operates when it is confirmed that the cover body 110 is mounted on the pen type injection device 10 through the installation sensor 111 .

In the case of the present invention, while efficiently using as little power as possible through a combination of a phase change material and a temperature control means, while minimizing temperature change within a predetermined storage temperature range or maintaining a constant temperature even for a long time There is an advantage in that it is possible to continuously maintain a constant temperature of the drug cartridge of the pen-type injection device.

In addition, there is an advantage that it is possible to provide a temperature maintenance system of a pen-type injection device capable of continuously measuring and managing the temperature of the drug cartridge, managing it in conjunction with a smart device, or warning of an abnormal temperature.

Figure 1: A view showing the configuration of a cover-type temperature maintaining system of a pen-type injection device according to an embodiment of the present invention
Figure 2: A graph showing temperature change over time when only a phase change material coolant is used
Figure 3: A graph showing temperature change over time when only the temperature control means is used
Figure 4: A graph showing temperature change over time when using a combination of a phase change material coolant and a temperature control means

Hereinafter, with reference to the accompanying drawings, a cover-type temperature maintenance system of a pen-type injection device according to an embodiment of the present invention will be described in detail. First of all, it should be noted that among the drawings, the same components or parts are indicated by the same reference numerals as much as possible. In describing the present invention, detailed descriptions of related well-known functions or configurations are omitted in order not to obscure the gist of the present invention.

First, a pen-type injection device 10 equipped with a cover-type temperature maintaining system of a pen-type injection device according to an embodiment of the present invention will be briefly described.

As described above, the pen-type injection device 10 has various standards, sizes, shapes, etc., but has a common point in that it injects a drug as much as the set dose after basically setting a dose.

As shown in FIG. 1, the pen-type injection device 10 generally includes a drug cartridge 11 in which a drug to be injected is stored, a dose setting means 12 for setting a drug dose, and an injection button for starting injection. (13), an injection driving unit 14 that operates to inject the drug of the drug cartridge 11, and a main control unit 15 that controls such dosage setting and operation. On the other hand, the pen-type injection device 10 may be configured to further include an operation display 16 for displaying a dose setting value or operation status. Since the technology constituting the pen-type injection device 10 is widely known and practiced, a detailed description thereof will be omitted.

Next, a cover-type temperature maintenance system 100 of a pen-type injection device according to an embodiment of the present invention will be described.

As shown in FIG. 1, the cover-type temperature maintaining system 100 of a pen-type injection device according to an embodiment of the present invention largely includes a cover body 110, a phase change material coolant 120, a temperature control means 130, and a temperature It is configured to include a control unit 140.

As shown in FIG. 1, the cover body 110 covers the drug cartridge 11 and is configured to be detachably mounted on the pen-type injection device 10 in the form of a cover.

Meanwhile, the cover body 110 preferably includes a heat insulating layer or is made of a material that is advantageous for heat insulation in order to insulate the phase change material coolant 120 from the outside.

Next, the phase change material coolant 120 will be described. The phase change material coolant 120 includes a phase change material (PCM) and is installed inside the cover body 110 . The phase change material (PCM) is a material with high potential latent heat capable of storing and releasing a large amount of energy at a specific temperature. A substance that stores heat in the form of a latent heat melting point that is about 100 times higher. On the other hand, the phase change material (PCM: Phase Change Material) is a temperature at which a phase change occurs (that is, a temperature at which a constant temperature is maintained while storing or releasing heat: below, 'set temperature (Ts)', depending on the material and composition used. )'.) can be set by adjusting. Therefore, the set temperature (Ts) is a temperature suitable for maintaining the temperature of the drug cartridge 11 used in the pen-type injection device 10 (for example, in the case of insulin, an appropriate temperature during storage and carrying (2 ° C. to 4 ° C. to 4 ° C.) ℃ range)) is preferably set.

Next, the temperature control means 130 will be described. As shown in FIG. 1, the temperature control unit 130 is configured to be installed in the phase change material coolant 120, and transfers heat to the phase change material coolant 120 under the control of the temperature controller 140. (heating) or taking heat from the phase change material coolant 120 (cooling).

As an embodiment constituting the temperature control means 130, various embodiments are possible, but it is possible to perform continuous and continuous cooling operation for a long time, and at the same time, the volume is small and it is easy to control to maintain a predetermined cooling temperature. Considering that, it is preferable to implement using a thermoelectric element (Peltier element).

In addition, it is preferable that a plurality of the temperature control means 130 be dispersed and installed in the phase change material coolant 120 so that the entire phase change material coolant 120 can have a uniform temperature distribution state as much as possible. do.

Next, the temperature controller 140 will be described. As shown in FIG. 1 , the temperature controller 140 sets the temperature of the phase change material coolant 120 according to the temperature measured by the inner temperature sensor 141 installed inside the cover body 110. It is configured to control the operation of the temperature control means 130 to maintain the temperature Ts. That is, the temperature control unit 140 controls the temperature control unit 130 to perform a cooling operation when the temperature measured by the inside temperature sensor 141 is higher than the set temperature Ts by a predetermined temperature difference, and the inside temperature When the temperature measured by the sensor 141 is lower than the set temperature Ts by a predetermined temperature difference or more, the temperature adjusting unit 130 is configured to control the cooling operation.

On the other hand, when insulin is exposed to air, it is oxidized very quickly, and fungi may proliferate in the air. Therefore, when the patient fastens the lid without disinfecting the lid with alcohol cotton or the like after use, mold can easily proliferate. In particular, since the cover body 110 is used repeatedly together with the pen-type injection device 10, it has a cover shape that makes it difficult to easily clean or disinfect the inside, so that the possibility of bacterial or mold growth increases. have a configuration Therefore, the cover-type temperature maintaining system 100 of the pen-type injection device, as shown in FIG. It is preferable to be configured to further include an ultraviolet ray disinfection means 170 installed inside.

On the other hand, it is connected to the temperature controller 140 as shown in FIG. 1 so that the temperature of the drug cartridge 11 is continuously measured and managed, managed in conjunction with a smart device, or warned of an abnormal temperature. It is preferable to further include a wireless communication unit 160 for wirelessly transmitting data including the temperature measured by the temperature sensor 141 to an external terminal 200 . In this case, the external terminal 200 manages the history of the temperature measured by the temperature sensor 141, and is configured to perform a notification function corresponding to the user when the temperature exceeds a predetermined temperature range from the set temperature Ts. it is desirable to be

In this case, the external terminal 200 may be a personal computer, a portable terminal, or an internet of things based terminal. In FIG. 1, the external terminal 200 is shown in a shape similar to a smart phone, but the spirit of the present invention is not limited thereto, and as described above, a terminal loaded with a terminal application can be borrowed without limitation. .

In addition, the wireless communication unit 160 and the external terminal 200 can be connected not only through direct wireless communication, but also through a communication network (N). The communication network N may cover wireless networks such as wireless LANs, CDMA, Bluetooth, satellite communication, etc., but the scope of the present invention is not limited thereto.

As a possible embodiment of the present invention, the cover type temperature maintaining system 100 of the pen type injection device of the present invention, as shown in FIG. 1, determines whether the cover body 110 is mounted on the pen type injection device 10. It is configured to further include a mounting sensor 111 that senses, and the temperature controller 140 determines that the cover body 110 is mounted on the pen-type injection device 10 through the mounting sensor 111. It is preferable to perform a temperature maintenance operation. That is, it is preferable that the cover body 110 is mounted on the pen-type injection device 10 so that it operates only when a temperature maintenance operation is required to enable efficient operation.

Meanwhile, the cover-type temperature maintaining system 100 of the pen-type injection device of the present invention may include a power supply unit 150 for supplying power for operation as shown in FIG. 1 . In this case, the power supply unit 150 can not only be built into the cover body 110 and installed, but also use the power of the pen-type injection device 10 or a separate external power source.

Hereinafter, the operating characteristics of the cover-type temperature maintaining system 100 of the pen-type injection device according to an embodiment of the present invention will be described. Meanwhile, the following description describes a case in which cooling (or cooling) is required because the external temperature is higher than the set temperature (Ts), but conversely, even when the external temperature is lower than the set temperature (Ts) and warming (or heating) is required. can be applied and interpreted.

First, as shown in FIG. 2, looking at the temperature change over time in the case of using only the phase change material coolant, the phase change material coolant has an initial temperature obtained through refrigerated storage, etc., as time elapses, heat from the outside Even during the transfer process, the phase change material performs a cooling function while maintaining the phase change temperature of the coolant. However, when the entire phase of the phase change material coolant is changed after a certain period of time has elapsed, the temperature gradually rises due to external heat thereafter, so that the cooling effect cannot be expected anymore.

Next, as shown in FIG. 3, looking at the temperature change over time when only the temperature control means is used, when the temperature measured using a temperature sensor or the like is higher than the predetermined set temperature Ts, the temperature control means (in this case The 'cooling' operation) operates to lower the temperature, and when the temperature drops to a certain extent, the process of stopping the operation of the temperature control unit is repeated to perform the cooling function. However, in this case, as can be seen in FIG. 3, there is a problem in that temperature fluctuations continuously occur and energy must be continuously consumed for cold storage.

Finally, as in the cover-type temperature maintenance system 100 of a pen-type injection device according to an embodiment of the present invention, when a phase change material coolant and a temperature control means are used in combination, as shown in FIG. 4,

1) The phase change material coolant performs a cooling function while maintaining the phase change temperature of the phase change material coolant even in the process of transferring heat from the outside as time elapses from the initial temperature obtained through refrigerated storage,

2) When the temperature measured using a temperature sensor or the like is higher than the predetermined set temperature (Ts), the temperature control means (in this case, 'cooling' operation) is operated. In this case, unlike the case in which the temperature decreases when the cooling operation starts when only the temperature control means is used, the phase change material refrigerant undergoes a phase change again during the cooling process at a constant temperature (phase change temperature = set temperature (Ts)) will keep

3) After that, when it is sensed that the phase change according to the cooling of the entire coolant of the phase change material is completed and the temperature decreases according to the cooling operation, the operation of the temperature control means is stopped.

Therefore, the cover-type temperature maintenance system 100 of the pen-type injection device according to an embodiment of the present invention uses a combination of a phase change material coolant and a temperature control means, so that the above steps 1) to 3) During most of the repetitive cooling operations, temperature fluctuations hardly occur, so that it is possible to stably maintain a constant temperature (phase change temperature = set temperature (Ts)), as well as to prevent the temperature control means from operating. Since overall time can also be reduced, operating efficiency can be increased while minimizing power consumption.

In the above, optimal embodiments have been disclosed in the drawings and specifications. Although specific terms have been used herein, they are only used for the purpose of describing the present invention and are not used to limit the scope of the present invention described in the claims. Therefore, those skilled in the art will understand that various modifications and equivalent other embodiments are possible therefrom. Therefore, the true technical scope of protection of the present invention should be determined by the technical spirit of the appended claims.

10: pen type injection device
11: drug cartridge 12: dose setting means
13: injection button 14: injection drive unit
15: main controller 16: display
100: cover type temperature maintenance system of pen type injection device
110: cover body
120: phase change material coolant
130: temperature control means
140: temperature controller 141: inner temperature sensor
150: power supply
160: wireless communication unit
170: UV disinfection means
200: external terminal
N: network

Claims (4)

A cover body 110 that covers the drug cartridge 11 and is detachably mounted to the pen-type injection device 10;
a phase change material coolant 120 installed inside the cover body 110;
A temperature control means 130 installed in the phase change material coolant 120;
According to the temperature measured by the inner temperature sensor 141 installed inside the cover body 110, the temperature control means 130 maintains the temperature of the phase change material coolant 120 at a predetermined set temperature Ts Temperature controller 140 for controlling the operation of; A cover-type temperature maintenance system 100 of a pen-type injection device, characterized in that configured to include.
According to claim 1,
an ultraviolet sterilization unit 170 installed inside the cover body 110 to irradiate the injection needle mounted on the drug cartridge 11; The cover-type temperature maintenance system 100 of the pen-type injection device, characterized in that configured to further include.
According to claim 1,
A wireless communication unit 160 that is connected to the temperature control unit 140 and wirelessly transmits data including the temperature measured by the temperature sensor 141 to an external terminal 200 directly or through a wireless communication room N. ); It is composed of further including,
The external terminal 200 manages the history of the temperature measured by the temperature sensor 141, and performs a notification function when the temperature exceeds a predetermined temperature range from the set temperature Ts. Cover type temperature maintenance system (100). According to claim 1,
a mounting sensor 111 for detecting whether the cover body 110 is mounted on the pen type injection device 10; It is composed of further including,
The temperature controller 140 operates when it is confirmed through the mounting sensor 111 that the cover body 110 is mounted on the pen-type injection device 10, characterized in that the cover-type temperature of the pen-type injection device Maintenance system (100).

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