KR20220145438A - CRISPR/Cas12f1 시스템 효율화를 위한 엔지니어링 된 가이드 RNA 및 그 용도 - Google Patents

CRISPR/Cas12f1 시스템 효율화를 위한 엔지니어링 된 가이드 RNA 및 그 용도 Download PDF

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KR20220145438A
KR20220145438A KR1020210051552A KR20210051552A KR20220145438A KR 20220145438 A KR20220145438 A KR 20220145438A KR 1020210051552 A KR1020210051552 A KR 1020210051552A KR 20210051552 A KR20210051552 A KR 20210051552A KR 20220145438 A KR20220145438 A KR 20220145438A
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seq
sequence
engineered
cas12f1
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KR1020210051552A
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English (en)
Korean (ko)
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김용삼
김도연
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주식회사 진코어
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Priority to KR1020210051552A priority Critical patent/KR20220145438A/ko
Priority to PCT/KR2021/013923 priority patent/WO2022075813A1/ko
Priority to CN202180082426.4A priority patent/CN116806261A/zh
Priority to JP2023521464A priority patent/JP2023544817A/ja
Priority to CA3198429A priority patent/CA3198429A1/en
Priority to EP21878063.3A priority patent/EP4227411A1/en
Priority to AU2021357377A priority patent/AU2021357377A1/en
Publication of KR20220145438A publication Critical patent/KR20220145438A/ko

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    • CCHEMISTRY; METALLURGY
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • CCHEMISTRY; METALLURGY
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90Stable introduction of foreign DNA into chromosome
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22Ribonucleases RNAses, DNAses
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    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/20Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPRs]

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KR1020210051552A 2020-10-08 2021-04-21 CRISPR/Cas12f1 시스템 효율화를 위한 엔지니어링 된 가이드 RNA 및 그 용도 KR20220145438A (ko)

Priority Applications (7)

Application Number Priority Date Filing Date Title
KR1020210051552A KR20220145438A (ko) 2021-04-21 2021-04-21 CRISPR/Cas12f1 시스템 효율화를 위한 엔지니어링 된 가이드 RNA 및 그 용도
PCT/KR2021/013923 WO2022075813A1 (ko) 2020-10-08 2021-10-08 Crispr/cas12f1 시스템 효율화를 위한 엔지니어링 된 가이드 rna 및 그 용도
CN202180082426.4A CN116806261A (zh) 2020-10-08 2021-10-08 用于增加CRISPR/Cas12f1系统的效率的经工程化的引导RNA及其用途
JP2023521464A JP2023544817A (ja) 2020-10-08 2021-10-08 CRISPR/Cas12f1システム効率化のためのエンジニアリングされたガイドRNAおよびその用途
CA3198429A CA3198429A1 (en) 2020-10-08 2021-10-08 Engineered guide rna for optimized crispr/cas12f1 system and use thereof
EP21878063.3A EP4227411A1 (en) 2020-10-08 2021-10-08 Engineered guide rna for increasing efficiency of crispr/cas12f1 system, and use of same
AU2021357377A AU2021357377A1 (en) 2020-10-08 2021-10-08 Engineered guide RNA for optimized CRISPR/Cas12f1 (Cas14a1) system and use thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020210051552A KR20220145438A (ko) 2021-04-21 2021-04-21 CRISPR/Cas12f1 시스템 효율화를 위한 엔지니어링 된 가이드 RNA 및 그 용도

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KR20220145438A true KR20220145438A (ko) 2022-10-31

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KR1020210051552A KR20220145438A (ko) 2020-10-08 2021-04-21 CRISPR/Cas12f1 시스템 효율화를 위한 엔지니어링 된 가이드 RNA 및 그 용도

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CN (1) CN116806261A (zh)

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CN116806261A (zh) 2023-09-26

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