KR20220133067A - Skin contact type medical semiconductor using divalent metal oxide film for musculoskeletal pain relief and method of delivering ions using the same - Google Patents

Abstract

The present invention relates to a medical semiconductor including a skin-contacting magnesium-based alloy and oxide, and an article including the same. According to the present invention, a magnesium-based alloy product including a magnesium-based alloy material and an oxide film formed on a part of the surface of the magnesium-based alloy material is brought into contact with the human skin, and metal ions are delivered from the magnesium-based alloy product to the skin in a transdermal delivery method. By developing a medical semiconductor used to alleviate musculoskeletal pain by being in contact a divalent metal (magnesium alloy) oxide film semiconductor with the skin, excellent pain relief effects can be provided only by delivery of cofactors without coenzymes for pain relief. Also, it is possible to provide a semiconductor capable of using a body fluid electrolyte when being in contact with the human skin without an electrolyte, and provide a semiconductor that can deliver ions directly into the body at the contact site through the skin without oral administration through a targeting transdermal ion delivery system.

Description

SKIN CONTACT TYPE MEDICAL SEMICONDUCTOR USING DIVALENT METAL OXIDE FILM FOR MUSCULOSKELETAL PAIN RELIEF AND METHOD OF DELIVERING IONS USING THE SAME }

Skeletal muscle pain is mainly a nerve problem, and when the nerve is stimulated, an action potential is generated, depolarization occurs and a potential difference occurs, and sodium/potassium ion channel (Na+/ Acetylcholine, a substance that induces regurgitation and nociception of K+ ion channels) is secreted.

In order to solve this problem, various kinds of methods have been proposed. These measures include, for example, low-frequency treatment to rectify the pulsation in the pain area, magnetic treatment to polarize the depolarization of the pain area, and the loss of negative (-) electricity in the pain area. It includes electric potential treatment, which regulates the potential difference by charging, and thermos treatment, which heats the cold painful area due to the backflow of ions from which sweat enters and potassium comes out. However, the pain relief in the painful area was insufficient with these individual methods of treatment, and there was no treatment device for the decomposition of nociceptive substances.

Accordingly, the present invention provides a method for transdermal delivery of a cofactor for pain relief without coenzyme, including rectification (low frequency treatment), polarization (magnet treatment), heat (thermal treatment), charging (potential treatment) and It aims to actuate the decomposition action simultaneously.

In particular, the decomposition action is intended to provide the action of decomposing acetylcholine, a nociceptive substance, to the synapse of the pain site. Specifically, when acetylcholine is hydrolyzed, it is decomposed into choline and acetic acid to relieve pain. In particular, in order to activate this decomposition, the supply of divalent metal ions is required. The present invention relates to a semiconductor including 90% or more of magnesium and a magnesium alloy including zinc, iron, copper, manganese, silicon, aluminum, etc. Use of devices or health-promoting devices. Through this, the above-mentioned five actions can be delivered at the same time, and pain can be quickly relieved and eliminated.

Most of skeletal muscle pain is a nerve problem, and when acetylcholine, a nociceptive substance, is secreted at the synapse of nerve cells in the pain area, pain is induced. can be mitigated or eliminated.

[reaction formula]

Acetylcholine + H ₂ O = choline + acetic acids

In order to degrade acetylcholine through this reaction, an acetylcholine esterase enzyme, a coenzyme, and a cofactor are required. In particular, coenzymes and cofactors have been recognized as essential for degradative activation, and conventionally, they have been provided by oral administration. However, this oral administration method requires both a coenzyme and a cofactor, and the oral administration method is often cumbersome. In addition, it is time to study how to provide the aforementioned five actions (eg, rectification, polarization, warming, charging and decomposition).

Registered Patent Publication No. 10-0389703

The inventor of the present invention has developed a medical semiconductor used to improve musculoskeletal pain by bringing a divalent metal (magnesium alloy) oxide film semiconductor into contact with the skin.

Specifically, the present invention intends to provide pain relief and improvement only by delivery of cofactors through transdermal delivery without coenzymes, as will be described later. In particular, an object of the present invention is to provide a semiconductor (MOS) in which an oxide film is formed on a metal surface that is manufactured by anodizing a magnesium alloy bundle to deliver ions through the transdermal layer, but omitting sealing.

The metal oxide semiconductor of the present invention has the same structure as the half electrolytic capacitor. The structure of a general electrolytic capacitor is composed of metal + insulator + electrolyte, while the half electrolytic capacitor is composed of metal + insulator without electrolyte. When such a half-capacitor comes into contact with the skin, the body fluid acts as an electrolyte to form a structure of metal + insulator + body fluid electrolyte, which can serve as a complete electrolytic capacitor.

Such a semiconductor is made of an alloy such as 90% magnesium or more and silicon. When the alloy bundle of magnesium and silicon is oxidized, a silicon dioxide film is formed on the metal surface, which becomes a metal oxide film semiconductor.

During anodization, the alloy is immersed in an electrolytic cell containing an alkali solution, produced by anodization and cathodic reduction, and fine electric charge is transferred by contact with the electrolyte solution of body fluids such as sweat on the skin. The electrolyte in the electrolyzer and the electrolyte in the skin body fluid are the same alkaline solution.

When these semiconductors are in close contact with the skin of the painful area, they act as electrolytic capacitors for rectification/polarization/charging/heating/decomposition, thereby providing effects such as low-frequency therapy/magnet therapy/potential therapy/thermal therapy/decomposition therapy at the same time. Specifically, when such a semiconductor is in close contact with the skin of a painful area, magnesium can be delivered directly through the skin without oral administration. By the electrochemical gradient inside and outside the skin, the ions are transported from a high concentration to a low concentration.

In one embodiment of the present invention, a magnesium-based alloy article including a magnesium-based alloy material and an oxide film formed on a portion of the surface of the magnesium-based alloy material is brought into contact with the skin of the human body, and metal ions are delivered transdermally from the magnesium-based alloy article. A method for delivery into the skin in a manner is provided.

In one embodiment, the magnesium-based alloy material may include manganese.

In one embodiment, the magnesium-based alloy material may include at least one selected from the group consisting of aluminum, zinc, manganese, silicon, iron, and copper.

In one embodiment, the magnesium-based alloy material is 0.1 to 0.3% by weight of aluminium, 0.2 to 0.4% by weight of zinc, 1.3 to 2.5% by weight of manganese, 0.01 to 0.2% by weight of silicon, 0.01 to 0.1% by weight of iron, 0.01 to 0.1% by weight of copper 0.1% by weight and the balance magnesium.

In an embodiment, the oxide may include at least one selected from the group consisting of magnesium oxide, silicon oxide, and aluminum oxide.

In one embodiment, when the magnesium-based alloy article is in contact with the skin, the body fluid acts as an electrolyte, and the magnesium-based alloy article may be a semiconductor composed of a magnesium-based alloy material, an oxide film, and an electrolyte.

In one embodiment, the magnesium-based alloy article may be applied to any one of a patch, an accessory, a waistband, a net, bedding, a pad, a metal mask, an insole, a mat, a mat, or a warmer.

According to the skin contact type medical semiconductor using a divalent metal oxide film semiconductor for improving musculoskeletal pain according to an embodiment of the present invention and a method for delivering ions using the same, excellent pain improvement only by delivery of cofactors without coenzyme for pain improvement effect can be provided.

According to an embodiment of the present invention, a skin-contact type medical semiconductor using a bivalent metal oxide film semiconductor for improving musculoskeletal pain and a method for transferring ions using the same semiconductors can be provided.

According to the skin contact type medical semiconductor using the divalent metal oxide film semiconductor for improving musculoskeletal pain according to an embodiment of the present invention and the ion delivery method using the same, the ions are delivered directly into the body of the contact site through the skin without oral administration It is possible to provide a semiconductor capable of (Targeting Transdermal Ion delivery system).

1 is a schematic diagram of a magnesium-based alloy article in the form of a patch according to an embodiment of the present invention.
2 is a schematic diagram of a waist belt-type magnesium-based alloy article according to an embodiment of the present invention.
3 is a schematic view of a skin-contacting accessory type magnesium-based alloy article according to an embodiment of the present invention.
4 is a schematic diagram for explaining a method of applying the magnesium-based alloy article according to an embodiment of the present invention to back pain, hip pain, and sciatic pain.
5 is a schematic diagram for explaining a method of applying a magnesium-based alloy article according to an embodiment of the present invention for shoulder pain.
6 is a schematic diagram for explaining a method of applying a magnesium-based alloy article to the forearm according to an embodiment of the present invention.
7 is a schematic diagram for explaining a method of applying a magnesium-based alloy article according to an embodiment of the present invention to plantar heel pain.
8 is a schematic diagram for explaining a method of applying a magnesium-based alloy article according to an embodiment of the present invention for wrist pain.
9 is a schematic diagram for explaining a method of applying a magnesium-based alloy article according to an embodiment of the present invention to tailbone pain.
10 is a schematic diagram for explaining a method of applying a magnesium-based alloy article according to an embodiment of the present invention for knee pain.
11 is a schematic diagram for explaining a method of applying a magnesium-based alloy article according to an embodiment of the present invention to popliteal pain.
12 is a schematic diagram for explaining a method of applying a magnesium-based alloy article according to an embodiment of the present invention for back pain.
13 is a view illustrating a state in which a magnesium-based alloy article according to an embodiment of the present invention is applied to a patch.
14 is a view showing a state in which the magnesium-based alloy article according to an embodiment of the present invention is applied to the shoe insole.
15 is a view illustrating a state in which a magnesium-based alloy article according to an embodiment of the present invention is applied to a floor plate.
16 is a view illustrating a state in which a magnesium-based alloy article according to an embodiment of the present invention is applied to a warmer.

The terms used in the present invention are only used to describe specific embodiments, and are not intended to limit the present invention. The singular expression includes the plural expression unless the context clearly dictates otherwise. In the present invention, terms such as “include” or “have” are intended to designate that the features, components, etc. described in the specification are present, and one or more other features or components may not be present or may be added. Doesn't mean there isn't.

Unless defined otherwise, all terms used herein, including technical or scientific terms, have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. Terms such as those defined in commonly used dictionaries should be interpreted as having meanings consistent with the meanings in the context of the related art, and should not be interpreted in an ideal or excessively formal meaning unless explicitly defined in the present invention. does not

Skeletal muscle pain is mainly a neurological problem, and when any stimulus is applied to the skeletal muscle, action potentials are generated and a potential difference occurs due to depolarization, and sodium/potassium ion channels (Na+/ K+ ion channel) reflux occurs and nociceptive substances are secreted.

Several devices have been proposed to treat such pain. In particular, a low-frequency treatment device has been proposed to rectify the pulsation caused by an action potential in the pain region, and a magnetic treatment device to polarize the depolarization of the pain region has been proposed. An electric potential treatment device that regulates the potential difference by charging the lost negative (-) electricity has been proposed, preventing the body temperature from falling due to the reverse flow of ions (Na+/K+) from which sweat enters the pain area and potassium comes out. In order to do this, a thermos treatment device has been proposed, but a device that performs these actions at the same time has not been proposed, and in particular, there is nothing about the decomposition treatment of nociceptive substances secreted on the synapse.

Unlike a conventional metal oxide semiconductor (Metal Oxide Semiconductor) having a metal, an insulator, and an electrolyte (metal + insulator + electrolyte), an embodiment of the present invention has a structure of a metal and an insulator (metal + insulator) without an electrolyte. can have

When such a device comes into contact with the skin, the body fluid becomes an electrolyte, and the structure of the electrolytic capacitor is complete with metal, insulator, and body fluid electrolyte (metal + insulator + body fluid electrolyte). When the semiconductor is in close contact with the body fluid of the skin at the pain site, it becomes a body fluid electrolyte with a metal, an insulator and a base, and ions can be delivered by the concentration difference.

Medical semiconductor (magnesium-based alloy article)

One embodiment of the present invention provides a magnesium-based alloy article. The magnesium-based alloy article of the present invention may be manufactured as a metal oxide film semiconductor by anodizing the magnesium alloy.

In one embodiment, the magnesium-based alloy article may include a magnesium-based alloy material and an oxide film formed on a portion of the surface of the magnesium-based alloy material.

Here, the magnesium-based alloy material may include manganese. More specifically, the magnesium-based alloy material may further include at least one selected from the group consisting of aluminum, zinc, manganese, silicon, iron, and copper.

Preferably, the magnesium-based alloy material is 0.1 to 0.3 wt% of aluminum, 0.2 to 0.4 wt% of zinc, 1.3 to 2.5 wt% of manganese, 0.01 to 0.2 wt% of silicon, 0.01 to 0.1 wt% of iron, 0.01 to 0.1 wt% of copper % and magnesium balance.

Most preferably, the magnesium-based alloy material may include 0.2% by weight of aluminum, 0.3% by weight of zinc, 1.3 to 2.5% by weight of manganese, 0.1% by weight of silicon, 0.05% by weight of iron, 0.05% by weight of copper, and the remaining amount of magnesium.

In an embodiment, the oxide may include at least one selected from the group consisting of magnesium oxide, silicon oxide, and aluminum oxide. As described above, an additional metal oxide may be formed because of the alloy metal included in addition to magnesium. The content of the corresponding metal oxide having a low content of the alloy metal is also small, and thus a significant effect may not be provided.

In one embodiment, when the magnesium-based alloy article is in contact with the skin, the body fluid acts as an electrolyte, and the magnesium-based alloy article may be a semiconductor composed of a magnesium-based alloy material, an oxide film, and an electrolyte.

In particular, the main metal of the alloy article is an alloy of 90% or more magnesium.

When the magnesium-based alloy article of the present invention produced in this way is in close contact with the skin of the painful part of the human body, it becomes a structure of an intact half electrolytic capacitor, and various actions of a medical semiconductor (for example, rectification/polarization/charging/heating/decomposition) are performed. By performing the treatment, various treatments (eg, low-frequency therapy/magnet therapy/potential therapy/thermal therapy/decomposition therapy) can be provided.

An article or device according to an embodiment of the present invention is anodizing a magnesium alloy (Mg, Mn, Zn, Si, Al, Fe, Cu, etc.) to cope with the secretion of acetylcholine. Cofactors (magnesium, zinc, iron, copper, magnesium, zinc, iron, copper, It is an article or device that can deliver manganese, etc.).

The manufacture of a medical semiconductor according to an embodiment of the present invention includes magnesium (Mg), manganese (Mn), zinc (Zn), silicon (Si), aluminum (Al), iron (Fe), and copper (Cu). ) may be anodized to form a metal oxide semiconductor (MOS).

When the magnesium alloy (metal) is anodized, a metal oxide such as a magnesium oxide (MgO) film, a silicon dioxide (SiO ₂ ) film, and an alumina oxide (Al ₂ O ₃ ) film formed on the surface of the metal is an insulating or insulator. It becomes a metal oxide semiconductor (MOS) in the form of a conductor and half of a conductor, which becomes a conductor only when an electrolyte or an electrolyte is in contact.

The present invention provides a method for directly delivering magnesium, zinc, iron, copper, manganese, etc., which are cofactors of acetyl choline esterase enzyme, through the skin without oral administration (Targeting transdermal ion delivery system) In order to apply, the semiconductor for a medical device according to an embodiment of the present invention is brought into close contact with or in contact with the skin of the painful area, thereby causing a chemical reaction with body fluid (from a high concentration to a low concentration of the ions by an electrochemical gradient inside and outside the skin). movement) can cause the delivery of ions.

As an embodiment, in the process of anodizing the magnesium alloy, when the magnesium alloy (including Zn, Fe, Cu, Mn, Si, Al, etc.) is immersed in an electrolytic bath containing alkaline solutions Na+, K+, etc., Assuming that the ions in the alloy and the ions in the electrolytic cell are replaced, an oxide film is formed on the surface of the magnesium alloy to form a semiconductor. Electrolysis occurs again by contact with body fluids electrolytes (Na, K, Cl, Ca, Mg, P, Bicarbonate, Protein, etc.) can Here, the electrolyte of the electrolytic cell and the body fluid are the same alkaline liquid, which is Na+ and K+.

As described above, magnesium, zinc, iron, copper, manganese, etc. made of divalent metal oxide semiconductors are substances that activate the hydrolysis of acetylcholine esterase enzyme, which is a nociceptive substance, and are used as coenzymes. ) as a cofactor.

In the present invention, a magnesium-based alloy is anodized to make a semiconductor. Specifically, when magnesium and a manganese-based alloy (metal) are oxidized, a magnesium oxide (MgO) film, a silicon dioxide (SiO ₂ ) film, an alumina oxide (Al ₂ O ₃ ) film, etc. are formed on the metal surface to form a metal oxide. A metal oxide semiconductor (MOS) is formed.

Transdermal delivery of cofactors

The metal oxide film semiconductor formed in this way is brought into contact with the skin of the pain site of the human skeletal muscle system, and a cofactor for accelerating (activating) the hydrolysis of acetylcholine esterase enzyme is delivered through the skin, thereby rapidly improving pain. can do.

Magnesium is used for the purpose of supplying the electrochemical function of increasing the electric current of the human body and the function of activating enzymes. In addition, manganese and iron can act as oxidizing agents that rapidly promote the production of ions in the human body. In addition, copper and zinc can function as redox enzymes in the body in low oxidation states.

The medical semiconductor of the present invention is applied to the skin of a pain area as a method of directly delivering magnesium-containing divalent metal elements (cofactors) through the skin without oral delivery (Targeting Transdermal Ion delivery system) When it is in close contact with or in contact with the body fluid, ion delivery can be performed by a chemical reaction with the body fluid.

The breakdown of acetylcholine

When the nociceptive substance acetylcholine is released at the synapse of the pain site, the pain-inducing action is lost when it is decomposed.

[reaction formula]

Acetylcholine + H ₂ O = choline + acetic acids

When acetylcholine, which is a pain-inducing substance in the above reaction formula, is hydrolyzed, it is decomposed into choline and acetic acid to improve pain. It was a situation in which the effect was not seen due to oral administration that could not be treated.

The metal oxide film semiconductor is made of a semiconductor by oxidizing a magnesium alloy (Mg, Mn, Zn, Si, Al, Fe, Cu, etc.).

In an embodiment of the present invention, the main metal of the semiconductor may be a magnesium alloy of 90% or more of magnesium. The medical semiconductor of the present invention, in which the above-described ions can be directly targeted and delivered to the skin of the contact site through the skin, can be provided as various articles.

Hereinafter, the present invention will be described in more detail.

The semiconductor article of the present invention can be used in a patch type, a skin contact accessory type, or a waist belt type.

As an example, it may be in the form of a patch, and the patch can improve pain by attaching it from as short as 50 minutes to as long as about 8 hours, and as another example, necklaces, bracelets, etc. It can improve pain.

1 shows a magnesium-based alloy article in the form of a patch according to an embodiment of the present invention.

As one embodiment, the patch is manufactured in a rectangular shape or a circular shape, and the size can be adjusted to about 10 Φmm, 20 Φmm, 30 Φmm, etc. in diameter, and it is also possible in the form of a wire. It can be manufactured in various shapes.

The thickness may be about 1 to 3 mm, but is not limited thereto.

The patch site may be a pain site or a spinal afferent nerve site, a back, shoulder, knee, sacrum, hip joint, sciatic bone, jangdanji, popliteal musculature pain site, such as the popliteal muscle, the sole of the foot, and the back.

As for the contact method, when there is body hair, after shaving, attach the semiconductor patch to the non-woven tape or cotton tape and attach it to the skin or use a band to contact the skin at the painful area.

In addition, by attaching a piece of a bivalent metal oxide semiconductor to the Velcro band to which the heat source of the rechargeable battery is applied, it can contact the back pain area. Figure 2 shows a magnesium-based alloy article in the form of a waist belt according to an embodiment of the present invention.

In addition, skin-contact type accessories can be used for various purposes other than the effect of improving musculoskeletal pain. In particular, wearing a necklace-type pendant can control heart rate and free from respiratory disorders, and can also take mental stability by awakening from EEG. In addition, rings and bracelets stimulate blood flow by stimulating peripheral nerves, and in the case of toothache due to periodontitis, the pain can be improved within about 30 minutes due to its anti-inflammatory action. Inflammatory skin such as bedsores can be improved within 24 hours by dehydrogenation. It may be a method of manufacturing a piece of bivalent metal oxide semiconductor equal to the area of pain in the chest pain as a pendant in the form of a necklace and hanging it. 3 shows a skin-contacting accessory type magnesium-based alloy article according to an embodiment of the present invention.

The use of the divalent metal oxide semiconductor of the present invention, which allows metal ions to be delivered directly into the body at the skin contact site through the skin, is non-toxic, biocompatible essential materials, and alkaline solution Na+, K+ in an electrolytic cell such as body fluid during the production process was used, and by targeting only the painful area, stability is maintained and it has the characteristic that it can be implemented at an industrially low price.

In addition, in order to provide chemotherapy other than the above-mentioned four medical devices (low-frequency therapy device, magnetic therapy device, potential therapy device, heat therapy device) and aluminum 90% or more alloy patch agent, zinc, iron, copper in 90% or more magnesium , manganese, silicon, aluminum, and the like to form a divalent metal oxide film semiconductor by adding a trace amount, it is possible to provide a more effective treatment device.

When the magnesium/manganese alloy bundle is annealed, it becomes a metal oxide semiconductor. When this semiconductor is attached to or brought into contact with body fluid of the skin at the pain site, a microscopic charge transfer occurs within the body fluid electrolyte. Charge transfer of magnesium, zinc, iron, copper, manganese, etc. works as a cofactor that activates the decomposition of acetylcholine, a nociceptive substance at the synapse in the pain area, thereby improving pain quickly and easily. In the past, dehydrogenation of pain areas was focused on using the sum of 90% aluminum, but in the present invention, the magnesium content was increased to 90% or more and activated as a cofactor.

Hereinafter, a pain site to which the present invention can be applied and an application method will be described.

Example 1: Improvement of Back Pain

Pain can be improved by attaching the above-mentioned semiconductor patch to the upper part of the coccyx for back pain, lumbar stenosis pain, hip joint pain/ sciatic pain/ weakness of the lower extremities, etc. 4 is a schematic diagram for explaining a method of applying the magnesium-based alloy article according to an embodiment of the present invention to back pain, hip pain, and sciatic pain. As shown in Figure 4, by attaching the patch in one row, it is possible to improve pain by attaching it to the upper part of the coccyx for back pain, lumbar stenosis pain, hip joint pain/ sciatic pain/ weakness of the lower extremities, etc.

Example 2: Shoulder Pain

In case of shoulder pain, the above-described semiconductor patch may be attached to the shoulder to improve pain. 5 is a schematic diagram for explaining a method of applying a magnesium-based alloy article according to an embodiment of the present invention for shoulder pain. As shown in FIG. 5 , when the head is tilted back, the pain can be improved by attaching a patch to a place where wrinkles are formed, a dent at the tip of the shoulder, and the like.

Example 3: Forearm Pain

In case of forearm pain, the above-described semiconductor patch may be attached to the forearm to improve pain. 6 is a schematic diagram for explaining a method of applying a magnesium-based alloy article according to an embodiment of the present invention for forearm pain. As shown in FIG. 6 , when the arm is bent, 2 to 3 patches are attached to the end of the wrinkled area, and the pain can be improved by attaching at intervals of 3 days.

Example 4: Plantar Heel Pain

In case of plantar heel pain, the above-described semiconductor patch may be attached to the plantar heel to improve pain. 7 is a schematic diagram for explaining a method of applying a magnesium-based alloy article according to an embodiment of the present invention to plantar heel pain. As shown in Figure 7, the patch is attached to about 10 pain points on the heel of the sole, and if it is both feet, it is transferred in the morning and evening, and transferred every 8 hours. Pain can be improved by attaching 6 patches.

Example 5: Wrist Pain

In case of wrist pain, the above-described semiconductor patch may be attached to the wrist to improve pain. 8 is a schematic diagram for explaining a method of applying a magnesium-based alloy article according to an embodiment of the present invention for wrist pain. As shown in FIG. 8 , pain can be improved by attaching a plurality of patches to a painful area of the wrist.

Example 6: Tailbone Pain

In case of tailbone pain, the above-described semiconductor patch may be attached to the tailbone to improve pain. 9 is a schematic diagram for explaining a method of applying a magnesium-based alloy article according to an embodiment of the present invention to tailbone pain. As shown in FIG. 9 , pain can be improved by attaching 2 to 3 patches to the painful area of the tailbone for 8 hours.

Example 7: Knee Pain

In case of knee pain, the above-described semiconductor patch may be attached to the knee to improve pain. 10 is a schematic diagram for explaining a method of applying a magnesium-based alloy article according to an embodiment of the present invention for knee pain. As shown in FIG. 10 , pain can be improved by attaching a knee pain area or knee eye patch.

Example 8: popliteal pain

In case of popliteal pain, the above-described semiconductor patch may be attached to the popliteal cavity to improve pain. 11 is a schematic diagram for explaining a method of applying a magnesium-based alloy article according to an embodiment of the present invention to popliteal pain. As shown in FIG. 11 , pain can be improved by attaching a patch to the wrinkled area behind the knee, the bulging area of the shin, and the area where the letter 'S' is displayed.

Example 9: Musculoskeletal Pain

In case of musculoskeletal pain, pain can be improved by finding and attaching the aforementioned semiconductor patch to the pain point.

Example 10: Back Pain

By attaching the above-described semiconductor article to the velcro band to which the heat source of the rechargeable battery is applied, the pain can be improved by contacting the back pain region. 12 is a schematic diagram for explaining a method of applying a magnesium-based alloy article according to an embodiment of the present invention for back pain. As shown in FIG. 12 , pain can be improved by wearing a magnesium alloy semiconductor band on the waist region.

Example 11: Finger Pain

Finger pain can be improved by wearing a ring-shaped accessory made of the above-described semiconductor for finger pain.

Example 12: Wrist Pain

In case of wrist pain, wrist pain can be improved by wearing the bracelet-type accessory made of the above-described semiconductor.

Example 13: Ankle Pain

Ankle pain can be improved by wearing an anklet-shaped accessory made of the above-described semiconductor during ankle pain.

Example 14: chest pain

In case of chest pain, it is possible to improve chest pain by wearing the necklace-type accessory made of the above-described semiconductor.

Example 15: Bedsores

The pressure sore or its pain can be improved by contacting the above-described net shape or patch made of the above-mentioned semiconductor to the pressure sore area.

Example 16: Bedding

Pain can be improved by attaching the above-described semiconductor to a part of the bedding that can be in contact with the skin.

Example 17: Mat

Pain can be improved by attaching the above-described semiconductor to a portion of the mat that can be in contact with the skin.

Example 18: Mask

Facial pain can be improved by a method of wearing the metal mask made of the above-described semiconductor during facial pain.

Example 19: Patch

As described above, pain can be improved by wearing the patch made of the semiconductor on the painful area in case of back pain, hip pain, sciatic pain, coccyx pain, and weakness in the lower extremities. 13 is a view illustrating a state in which a magnesium-based alloy article according to an embodiment of the present invention is applied to a patch.

Example 20: Insole

Pain can be improved by attaching the above-described semiconductor to a portion of the insole of a shoe that can be in contact with the skin. 14 is a view showing a state in which the magnesium-based alloy article according to an embodiment of the present invention is applied to the shoe insole.

Example 21: veneer

Pain can be improved by attaching the above-described semiconductor to a skin-contactable area of the veneer. 15 is a view illustrating a state in which a magnesium-based alloy article according to an embodiment of the present invention is applied to a floor plate.

Example 22: Warmer

A heater can be manufactured using the magnesium alloy material of the present invention. The external shape of the warmer is not particularly limited, but may include a handle so that a user can hold and use the warmer, and may include a heat transfer unit connected from the handle. 16 is a cross-sectional view of a heater using a magnesium alloy material according to an embodiment of the present invention. As shown in FIG. 16 , power is supplied from the outside, including the carbon fiber heating element 10 in the heat transfer unit within the warmer 100 , and heat is generated from the carbon fiber heating element 10 , which is a magnesium alloy. The effect of the above-described magnesium alloy material can be provided along with heat to the area of use of the user who uses the warmer 100 by being transferred to the material. In addition, a control unit (not shown) capable of driving and controlling the vibration motor 20 and the vibration motor 20 is included inside the handle, and power is supplied from the outside to drive the vibration motor 20 , so that the user's It is possible to provide an additional vibration effect to the area of use. However, as long as it is a heater capable of realizing the effect of a magnesium alloy material along with heat, it is not limited to this description and may be changed into various shapes and structures.

Although the present invention as described above has been described with reference to the embodiments shown in the drawings, it will be understood that this is merely an example, and that those skilled in the art can make various modifications and variations therefrom. However, such modifications should be considered to be within the technical protection scope of the present invention. Accordingly, the true technical protection scope of the present invention should be defined by the technical spirit of the appended claims.

Claims (7)

A magnesium-based alloy article including a magnesium-based alloy material and an oxide film formed on a portion of the surface of the magnesium-based alloy material is brought into contact with the skin of the human body, and metal ions from the magnesium-based alloy article are delivered into the skin in a transdermal delivery method. Way.
The method of claim 1,
The magnesium-based alloy material is a method comprising manganese.
The method of claim 1,
The magnesium-based alloy material includes at least one selected from the group consisting of aluminum, zinc, manganese, silicon, iron, and copper.
The method of claim 1,
The magnesium-based alloy material is 0.1 to 0.3% by weight of aluminum, 0.2 to 0.4% by weight of zinc, 1.3 to 2.5% by weight of manganese, 0.01 to 0.2% by weight of silicon, 0.01 to 0.1% by weight of iron, 0.01 to 0.1% by weight of copper, and magnesium How to include the balance.
The method of claim 1,
wherein the oxide comprises at least one selected from the group consisting of magnesium oxide, silicon oxide, and aluminum oxide.
6. The method according to any one of claims 1 to 5,
When the magnesium-based alloy article comes into contact with the skin of the human body, the body fluid acts as an electrolyte,
The magnesium-based alloy article is a method of operating as a semiconductor composed of a magnesium-based alloy material, an oxide film and an electrolyte.
7. The method of claim 6,
The magnesium-based alloy article is applied to any one of a patch, an accessory, a waistband, a net, bedding, a pad, a metal mask, an insole, a mat, a rug, or a warmer.

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